The Diversity of Intermediate Filaments in Astrocytes.
GFAP
astrocytes
cytolinker proteins
intermediate filaments
nestin
plectin
reactive gliosis
synemin
vimentin
Journal
Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052
Informations de publication
Date de publication:
02 07 2020
02 07 2020
Historique:
received:
04
06
2020
revised:
26
06
2020
accepted:
01
07
2020
entrez:
8
7
2020
pubmed:
8
7
2020
medline:
9
3
2021
Statut:
epublish
Résumé
Despite the remarkable complexity of the individual neuron and of neuronal circuits, it has been clear for quite a while that, in order to understand the functioning of the brain, the contribution of other cell types in the brain have to be accounted for. Among glial cells, astrocytes have multiple roles in orchestrating neuronal functions. Their communication with neurons by exchanging signaling molecules and removing molecules from extracellular space takes place at several levels and is governed by different cellular processes, supported by multiple cellular structures, including the cytoskeleton. Intermediate filaments in astrocytes are emerging as important integrators of cellular processes. Astrocytes express five types of intermediate filaments: glial fibrillary acidic protein (GFAP); vimentin; nestin; synemin; lamins. Variability, interactions with different cellular structures and the particular roles of individual intermediate filaments in astrocytes have been studied extensively in the case of GFAP and vimentin, but far less attention has been given to nestin, synemin and lamins. Similarly, the interplay between different types of cytoskeleton and the interaction between the cytoskeleton and membranous structures, which is mediated by cytolinker proteins, are understudied in astrocytes. The present review summarizes the basic properties of astrocytic intermediate filaments and of other cytoskeletal macromolecules, such as cytolinker proteins, and describes the current knowledge of their roles in normal physiological and pathological conditions.
Identifiants
pubmed: 32630739
pii: cells9071604
doi: 10.3390/cells9071604
pmc: PMC7408014
pii:
doi:
Substances chimiques
Intermediate Filament Proteins
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Références
Cell. 1981 Dec;27(3 Pt 2):419-28
pubmed: 6086105
Development. 2011 Feb;138(4):745-53
pubmed: 21266410
J Biol Chem. 1983 Dec 10;258(23):14610-8
pubmed: 6358225
Acta Neuropathol. 2010 Jan;119(1):7-35
pubmed: 20012068
Neuroreport. 1994 Oct 3;5(15):1885-8
pubmed: 7841369
Prog Neurobiol. 2011 Mar;93(3):421-43
pubmed: 21219963
Neurochem Int. 2004 Jul-Aug;45(2-3):191-202
pubmed: 15145537
Semin Cell Dev Biol. 2017 Sep;69:9-17
pubmed: 28579452
Proc Natl Acad Sci U S A. 2001 May 22;98(11):6156-61
pubmed: 11353857
Science. 1970 Jul 17;169(3942):286-8
pubmed: 4915821
J Virol. 2015 Oct;89(20):10230-46
pubmed: 26223645
Nature. 1986 Feb 6-12;319(6053):463-8
pubmed: 3453101
J Cereb Blood Flow Metab. 2008 Mar;28(3):468-81
pubmed: 17726492
Glia. 2013 Nov;61(11):1922-37
pubmed: 24009167
ASN Neuro. 2012 Mar 22;4(2):
pubmed: 22313347
Exp Cell Res. 2004 Aug 15;298(2):431-44
pubmed: 15265691
Eur J Biochem. 2001 Dec;268(24):6435-49
pubmed: 11737198
Cancer Res. 1992 Oct 1;52(19):5334-41
pubmed: 1382841
J Cell Biol. 2008 Apr 21;181(2):269-80
pubmed: 18426975
Proc Natl Acad Sci U S A. 1977 Jun;74(6):2422-6
pubmed: 329284
BMC Cell Biol. 2011 Nov 23;12:51
pubmed: 22107957
J Cell Biol. 2006 Jan 2;172(1):41-53
pubmed: 16380439
J Biol Chem. 1988 Aug 25;263(24):12135-41
pubmed: 3403563
Mol Biol Cell. 2013 Mar;24(6):768-84
pubmed: 23363598
J Biol Chem. 1999 Nov 19;274(47):33522-30
pubmed: 10559237
Cereb Cortex. 2019 Sep 13;29(10):4050-4066
pubmed: 30605503
Exp Cell Res. 2007 Jun 10;313(10):2189-203
pubmed: 17499243
Development. 1989 Feb;105(2):365-78
pubmed: 2680424
J Cell Biol. 2018 Sep 3;217(9):3031-3044
pubmed: 29980627
Hum Mol Genet. 2015 Jun 1;24(11):3155-62
pubmed: 25712130
Front Aging Neurosci. 2019 Feb 28;11:42
pubmed: 30873018
Cell. 1990 Feb 23;60(4):585-95
pubmed: 1689217
Acta Neuropathol. 2013 Jan;125(1):77-93
pubmed: 22864774
Neurosci Lett. 2014 Apr 17;565:30-8
pubmed: 24406153
Biomark Insights. 2012;7:71-9
pubmed: 22798722
J Neurosci. 1985 Dec;5(12):3310-28
pubmed: 4078630
J Biol Chem. 2001 Aug 24;276(34):32330-7
pubmed: 11418616
Cold Spring Harb Perspect Biol. 2010 Nov;2(11):a000547
pubmed: 20826548
Cell Mol Life Sci. 2016 Nov;73(21):4101-20
pubmed: 27141937
Cell. 1980 Dec;22(3):727-38
pubmed: 7006832
J Cell Biol. 1995 Oct;131(2):453-64
pubmed: 7593171
Cell Stem Cell. 2015 Nov 5;17(5):624-34
pubmed: 26456685
Proc Natl Acad Sci U S A. 1980 Aug;77(8):4808-12
pubmed: 6933530
Nature. 2017 Jan 26;541(7638):481-487
pubmed: 28099414
Science. 1994 Mar 25;263(5154):1768-71
pubmed: 8134839
Acta Neuropathol. 1986;72(1):43-54
pubmed: 3548203
Annu Rev Biochem. 2004;73:749-89
pubmed: 15189158
J Cell Biol. 1971 Dec;51(3):752-62
pubmed: 4942774
Ann N Y Acad Sci. 1985;455:126-43
pubmed: 2417512
Ther Targets Neurol Dis. 2014;1(1):
pubmed: 25590048
Eur J Cell Biol. 1981 Dec;26(1):68-82
pubmed: 6799297
Hear Res. 1994 Jun 1;76(1-2):118-26
pubmed: 7928704
Dev Biol. 1984 Mar;102(1):248-59
pubmed: 6538151
Neuron. 1999 Jun;23(2):297-308
pubmed: 10399936
J Invest Dermatol. 1989 Jan;92(1):33-8
pubmed: 2462597
J Mol Biol. 1996 Dec 20;264(5):933-53
pubmed: 9000622
Nat Rev Neurosci. 2006 Mar;7(3):194-206
pubmed: 16495941
APMIS. 2014 Jan;122(1):76-80
pubmed: 23594359
Neuron. 1991 Jun;6(6):983-92
pubmed: 1675864
J Cell Sci. 1992 Oct;103 ( Pt 2):589-97
pubmed: 1478958
J Mol Biol. 1961 Oct;3:640-7
pubmed: 13894768
Exp Cell Res. 1986 Jan;162(1):1-10
pubmed: 2415378
Eur J Biochem. 2004 May;271(10):1873-84
pubmed: 15128297
Glia. 2019 Aug;67(8):1417-1433
pubmed: 30667110
J Biol Chem. 1983 Feb 25;258(4):2710-9
pubmed: 6218170
Brain Res. 2004 Oct 22;1024(1-2):193-202
pubmed: 15451382
Glia. 2013 Jun;61(6):917-28
pubmed: 23505074
Am J Hum Genet. 2002 Mar;70(3):726-36
pubmed: 11799477
Neurosci Res. 2013 Mar;75(3):204-9
pubmed: 23396245
J Cell Sci. 1994 Aug;107 ( Pt 8):2299-311
pubmed: 7983188
J Cell Biol. 1983 Sep;97(3):887-901
pubmed: 6350322
Hum Mol Genet. 1999 Dec;8(13):2461-72
pubmed: 10556294
Histochem Cell Biol. 2013 Jul;140(1):33-53
pubmed: 23748243
Mol Neurobiol. 2020 Mar;57(3):1748-1767
pubmed: 31836945
Glia. 2000 Apr;30(2):143-53
pubmed: 10719356
Nat Rev Neurol. 2016 Jul;12(7):403-12
pubmed: 27340021
Brain Res. 1972 Feb 11;37(1):81-9
pubmed: 4621897
Science. 1990 Jan 26;247(4941):470-3
pubmed: 1967852
Sci Rep. 2017 Jul 7;7(1):4897
pubmed: 28687747
Hum Mol Genet. 2005 Dec 1;14(23):3661-71
pubmed: 16239243
PLoS One. 2012;7(12):e51469
pubmed: 23251543
Exp Neurol. 2018 Oct;308:72-79
pubmed: 30008424
Genomics. 1997 May 15;42(1):115-25
pubmed: 9177781
Proc Natl Acad Sci U S A. 1975 Mar;72(3):1007-11
pubmed: 1055359
Proc Natl Acad Sci U S A. 1989 Jul;86(13):5178-82
pubmed: 2740350
Acta Neuropathol. 1994;87(4):355-61
pubmed: 8017171
J Neurosci. 2012 May 2;32(18):6391-410
pubmed: 22553043
Cells. 2019 Mar 13;8(3):
pubmed: 30871242
Neuron. 1992 Sep;9(3):417-28
pubmed: 1524825
Proc Natl Acad Sci U S A. 1986 Jun;83(11):3839-43
pubmed: 2424013
Genes Dev. 1998 Nov 1;12(21):3442-51
pubmed: 9808630
Aging Cell. 2010 Jun;9(3):313-26
pubmed: 20121722
Acta Neuropathol Commun. 2016 Apr 27;4(1):44
pubmed: 27121971
J Neurosci. 2008 Jan 2;28(1):264-78
pubmed: 18171944
Nat Med. 2006 Jul;12(7):829-34
pubmed: 16783372
Exp Cell Res. 2007 Jun 10;313(10):2050-62
pubmed: 17512929
Cells. 2019 Sep 01;8(9):
pubmed: 31480524
Curr Biol. 2006 Mar 7;16(5):R147-51
pubmed: 16527727
Physiol Rev. 2014 Oct;94(4):1077-98
pubmed: 25287860
Glia. 1999 Feb 15;25(4):390-403
pubmed: 10028921
Glia. 2010 Aug;58(10):1208-19
pubmed: 20544856
Am J Pathol. 2006 Mar;168(3):888-97
pubmed: 16507904
Cells. 2016 Apr 25;5(2):
pubmed: 27120621
Cell Tissue Res. 2003 Aug;313(2):195-207
pubmed: 12845519
J Cell Biol. 1994 May;125(3):511-6
pubmed: 7513705
J Neurosci. 2004 May 26;24(21):5016-21
pubmed: 15163694
Nat Rev Mol Cell Biol. 2006 Oct;7(10):782-8
pubmed: 16926857
Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):E423-31
pubmed: 22308344
Proc Natl Acad Sci U S A. 1991 May 1;88(9):3812-6
pubmed: 2023931
BMC Biol. 2011 Feb 28;9:16
pubmed: 21356127
Traffic. 2007 Jan;8(1):12-20
pubmed: 17229312
J Neurosci Res. 1994 Mar 1;37(4):515-28
pubmed: 8021973
J Invest Dermatol. 1983 Jul;81(1 Suppl):149s-56s
pubmed: 6345689
Mol Biol Cell. 2003 Apr;14(4):1468-78
pubmed: 12686602
Acta Physiol (Oxf). 2020 Mar;228(3):e13399
pubmed: 31597221
J Neurosci. 1988 Apr;8(4):1144-51
pubmed: 3357014
J Cell Sci. 2004 Feb 29;117(Pt 6):919-32
pubmed: 14762106
J Cell Biol. 1999 May 3;145(3):503-14
pubmed: 10225952
Int J Oncol. 2017 Jan;50(1):310-316
pubmed: 27959385
J Neurochem. 2016 Jan;136(1):78-91
pubmed: 26490262
Mol Vis. 2010 Nov 27;16:2511-23
pubmed: 21139996
J Neurocytol. 1988 Feb;17(1):79-86
pubmed: 3047327
J Cell Biol. 1978 Jul;78(1):93-109
pubmed: 566763
Nature. 1980 Jan 17;283(5744):249-256
pubmed: 7188712
J Cell Sci. 1994 Jul;107 ( Pt 7):1959-72
pubmed: 7527050
Curr Opin Cell Biol. 2015 Feb;32:121-30
pubmed: 25726916
Nat Genet. 1994 Dec;8(4):323-7
pubmed: 7894480
Am J Med Genet A. 2007 Oct 1;143A(19):2256-60
pubmed: 17726686
Curr Opin Genet Dev. 1997 Jun;7(3):392-7
pubmed: 9229116
Curr Top Dev Biol. 2005;65:211-28
pubmed: 15642385
Nat Rev Neurosci. 2013 May;14(5):311-21
pubmed: 23595014
Cell. 1980 Jan;19(1):277-87
pubmed: 7357605
Glia. 2006 Aug 15;54(3):204-13
pubmed: 16817202
Nat Rev Cancer. 2015 May;15(5):290-301
pubmed: 25877329
J Comp Neurol. 2001 Jul 23;436(2):167-81
pubmed: 11438922
Curr Opin Cell Biol. 2000 Feb;12(1):79-90
pubmed: 10679360
Brain Res. 2009 May 13;1270:10-8
pubmed: 19306852
Glia. 2016 Sep;64(9):1518-31
pubmed: 27340757
Glia. 2008 Jan 15;56(2):135-44
pubmed: 17990309
Proc Natl Acad Sci U S A. 1992 Nov 15;89(22):11093-7
pubmed: 1332069
Neurol Med Chir (Tokyo). 2006 Mar;46(3):111-7
pubmed: 16565580
J Comp Neurol. 1966 Mar;126(3):337-89
pubmed: 5937257
J Cell Biol. 1968 Sep;38(3):538-55
pubmed: 5664223
J Cell Sci. 2001 Jul;114(Pt 14):2569-75
pubmed: 11683385
Front Cell Neurosci. 2017 Apr 19;11:104
pubmed: 28469559
Brain Tumor Pathol. 2012 Jul;29(3):160-7
pubmed: 22350668
J Neuroinflammation. 2012 Jun 26;9:144
pubmed: 22734718
Curr Biol. 2011 Jul 26;21(14):R529-31
pubmed: 21783027
J Biol Chem. 1999 Oct 8;274(41):29493-9
pubmed: 10506213
Mol Cell. 2010 May 28;38(4):603-13
pubmed: 20513434
Stem Cells. 2012 Oct;30(10):2320-9
pubmed: 22887872
J Cell Biol. 1999 Nov 29;147(5):913-20
pubmed: 10579712
Brain Res. 1971 May 7;28(2):351-4
pubmed: 5113526
Cell Stress. 2018 Sep 10;2(9):219-224
pubmed: 31223139
Curr Opin Cell Biol. 2018 Dec;55:1-7
pubmed: 30006050
Glia. 2007 Apr 1;55(5):508-15
pubmed: 17211868
Eur J Biochem. 1983 May 16;132(3):477-84
pubmed: 6682757
Brain Res. 2000 Feb 28;857(1-2):291-4
pubmed: 10700580
Lab Invest. 1992 Mar;66(3):303-13
pubmed: 1538585
Proc Natl Acad Sci U S A. 1978 Oct;75(10):5034-8
pubmed: 368806
Nature. 2013 May 16;497(7449):369-73
pubmed: 23615612
Brain. 2006 Jan;129(Pt 1):256-71
pubmed: 16246864
Int J Mol Sci. 2019 Oct 31;20(21):
pubmed: 31683640
J Biol Chem. 1999 Aug 20;274(34):23996-4006
pubmed: 10446168
Brain Res Mol Brain Res. 1998 Nov 12;62(1):77-81
pubmed: 9795147
Cell Mol Neurobiol. 2005 Nov;25(7):1141-50
pubmed: 16392042
Brain Res Dev Brain Res. 1995 Jan 14;84(1):109-29
pubmed: 7720210
J Cell Biol. 2017 Jun 5;216(6):1689-1703
pubmed: 28432079
Am J Anat. 1966 Jul;119(1):129-45
pubmed: 6007824
FASEB J. 2009 Aug;23(8):2710-26
pubmed: 19332645
J Cell Sci. 2007 Apr 1;120(Pt 7):1267-77
pubmed: 17356066
BMC Evol Biol. 2007 Sep 13;7:164
pubmed: 17854500
Exp Cell Res. 1982 Oct;141(2):385-95
pubmed: 6754394
J Biol Chem. 2000 Sep 22;275(38):29772-8
pubmed: 10887173
J Neurosci. 1995 Nov;15(11):7238-49
pubmed: 7472478
Nature. 1994 Jun 30;369(6483):744-7
pubmed: 7911978
Neurochem Res. 2020 Jan;45(1):215-220
pubmed: 31562576
Cell. 2013 Mar 14;152(6):1365-75
pubmed: 23498943
IBRO Rep. 2018 Nov 05;5:99-109
pubmed: 30505974
J Biol Chem. 1999 Apr 2;274(14):9881-90
pubmed: 10092680
EMBO J. 1995 Apr 18;14(8):1590-8
pubmed: 7737111
Brain Res Bull. 2018 Jan;136:130-138
pubmed: 28159699
Nat Genet. 1999 Mar;21(3):285-8
pubmed: 10080180
J Neuropathol Exp Neurol. 2004 Jun;63(6):631-40
pubmed: 15217091
Mol Biol Cell. 2011 May;22(9):1539-49
pubmed: 21346193
Int J Mol Sci. 2013 May 27;14(6):11238-58
pubmed: 23712361
FEBS Lett. 1995 Jul 24;368(3):500-4
pubmed: 7635207
J Cell Biol. 2013 Feb 4;200(3):249-58
pubmed: 23382461
Glia. 2005 Apr 15;50(2):107-20
pubmed: 15657940
FASEB J. 2014 Jul;28(7):2942-54
pubmed: 24696300
Biochem Biophys Res Commun. 1999 Oct 22;264(2):568-74
pubmed: 10529403
Curr Opin Cell Biol. 1992 Feb;4(1):99-104
pubmed: 1558758
J Mol Neurosci. 1999 Feb;12(1):11-22
pubmed: 10636467
Stroke. 1997 Apr;28(4):858-65
pubmed: 9099208
J Biol Chem. 2009 Sep 25;284(39):26502-9
pubmed: 19625254
Cell Tissue Res. 2015 Jun;360(3):529-44
pubmed: 26017636
J Neurochem. 2008 Aug;106(4):1914-28
pubmed: 18547370
Cell Biol Int Rep. 1992 Feb;16(2):165-74
pubmed: 1551147
Dev Neurosci. 1987;9(3):154-73
pubmed: 3678106
Neuron. 1992 Mar;8(3):429-40
pubmed: 1347996
Glia. 2005 Dec;52(4):289-300
pubmed: 16001427
J Cell Biol. 1981 Aug;90(2):435-47
pubmed: 7026573
Acta Neuropathol Commun. 2017 Mar 31;5(1):27
pubmed: 28359321
Cell Mol Life Sci. 2018 Jun;75(12):2177-2195
pubmed: 29541793
J Pathol. 2004 Nov;204(4):428-37
pubmed: 15495269
Trends Neurosci. 1999 May;22(5):208-15
pubmed: 10322493
J Neurosci. 2003 Nov 26;23(34):10944-52
pubmed: 14645490
J Proteome Res. 2016 Jul 1;15(7):2265-82
pubmed: 27193225
Mol Biol Cell. 2008 Oct;19(10):4521-33
pubmed: 18685083
Neuron. 1990 Oct;5(4):527-44
pubmed: 1698397
Proc Natl Acad Sci U S A. 1984 Apr;81(7):2102-6
pubmed: 6371809
J Clin Invest. 2009 Jul;119(7):1763-71
pubmed: 19587451
Am J Pathol. 1998 Jan;152(1):251-9
pubmed: 9422542
Nat Rev Mol Cell Biol. 2004 Jul;5(7):542-53
pubmed: 15232572
Free Radic Biol Med. 2018 May 20;120:380-394
pubmed: 29635011
Trends Cell Biol. 2018 Jan;28(1):34-45
pubmed: 28893461
Nat Neurosci. 2015 Nov;18(11):1539-1545
pubmed: 26505565