Association between lung function decline and obstructive sleep apnoea: the ALEC study.
Asthma
Lung function
Lung function decline
Sleep apnoea
Journal
Sleep & breathing = Schlaf & Atmung
ISSN: 1522-1709
Titre abrégé: Sleep Breath
Pays: Germany
ID NLM: 9804161
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
received:
24
01
2020
accepted:
13
04
2020
revised:
31
03
2020
pubmed:
8
7
2020
medline:
21
12
2021
entrez:
8
7
2020
Statut:
ppublish
Résumé
To study changes in lung function among individuals with a risk of obstructive sleep apnoea (OSA), and if asthma affected this relationship. We used data from the European Community Respiratory Health Survey II and III, a multicentre general population study. Participants answered questionnaires and performed spirometry at baseline and 10-year follow-up (n = 4,329 attended both visits). Subjects with high risk for OSA were identified from the multivariable apnoea prediction (MAP) index, calculated from BMI, age, gender, and OSA symptoms at follow-up. Asthma was defined as having doctor's diagnosed asthma at follow-up. Primary outcomes were changes in forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) from baseline to follow-up. Among 5108 participants at follow-up, 991 (19%) had a high risk of OSA based on the MAP index. Participants with high OSA risk more often had wheeze, cough, chest tightness, and breathlessness at follow-up than those with low OSA risk. Lung function declined more rapidly in subjects with high OSA risk (low vs high OSA risk [mean ± SD]: FEV1 = - 41.3 ± 24.3 ml/year vs - 50.8 ± 30.1 ml/year; FVC = - 30.5 ± 31.2 ml/year vs - 45.2 ± 36.3 ml/year). Lung function decline was primarily associated with higher BMI and OSA symptoms. OSA symptoms had a stronger association with lung function decline among asthmatics, compared to non-asthmatics. In the general population, a high probability of obstructive sleep apnoea was related to faster lung function decline in the previous decade. This was driven by a higher BMI and more OSA symptoms among these subjects. The association between OSA symptoms and lung function decline was stronger among asthmatics.
Identifiants
pubmed: 32632893
doi: 10.1007/s11325-020-02086-1
pii: 10.1007/s11325-020-02086-1
pmc: PMC8195766
doi:
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
587-596Subventions
Organisme : Horizon 2020
ID : 633212
Références
Franklin KA, Lindberg E (2015) Obstructive sleep apnea is a common disorder in the population—a review on the epidemiology of sleep apnea. J Thorac Dis 7(8):1311–1322
pubmed: 26380759
pmcid: 26380759
Arnardottir ES, Bjornsdottir E, Olafsdottir KA, Benediktsdottir B, Gislason T (2016) Obstructive sleep apnoea in the general population: highly prevalent but minimal symptoms. Eur Respir J 47(1):194–202
doi: 10.1183/13993003.01148-2015
Svensson M, Lindberg E, Naessen T, Janson C (2006) Risk factors associated with snoring in women with special emphasis on body mass index: a population-based study. Chest. 129(4):933–941
doi: 10.1378/chest.129.4.933
Torzsa P, Keszei A, Kalabay L, Vamos EP, Zoller R, Mucsi I et al (2011) Socio-demographic characteristics, health behaviour, co-morbidity and accidents in snorers: a population survey. Sleep Breath Schlaf Atmun 15(4):809–818
doi: 10.1007/s11325-010-0442-4
Lindberg E, Gislason T (2000) Epidemiology of sleep-related obstructive breathing. Sleep Med Rev 4(5):411–433
doi: 10.1053/smrv.2000.0118
Scheffler P, Pang KP, Rotenberg BW (2017) Should patients with primary snoring be screened for carotid artery stenosis? Laryngoscope. 127(12):2687–2688
doi: 10.1002/lary.26755
Pien GW, Ye L, Keenan BT, Maislin G, Bjornsdottir E, Arnardottir ES et al (2018) Changing faces of obstructive sleep apnea: treatment effects by cluster designation in the Icelandic sleep apnea cohort. Sleep 41(3):zsx201
Svensson M, Franklin KA, Theorell-Haglow J, Lindberg E (2008) Daytime sleepiness relates to snoring independent of the apnea-hypopnea index in women from the general population. Chest. 134(5):919–924
doi: 10.1378/chest.08-0847
Emilsson OI, Hagg SA, Lindberg E, Franklin KA, Toren K, Benediktsdottir B et al (2019) Snoring and nocturnal reflux: association with lung function decline and respiratory symptoms. ERJ Open Res 5(2):00010-2019
Kavanagh J, Jackson DJ, Kent BD (2018) Sleep and asthma. Curr Opin Pulm Med 24(6):569–573
doi: 10.1097/MCP.0000000000000526
Julien JY, Martin JG, Ernst P, Olivenstein R, Hamid Q, Lemiere C et al (2009) Prevalence of obstructive sleep apnea-hypopnea in severe versus moderate asthma. J Allergy Clin Immunol 124(2):371–376
doi: 10.1016/j.jaci.2009.05.016
Chan K, Ing A, Birring SS (2015) Cough in obstructive sleep apnoea. Pulm Pharmacol Ther 35:129–131
Prasad B, Nyenhuis SM, Imayama I, Siddiqi A, Teodorescu M (2019) Asthma and obstructive sleep apnea overlap: what has the evidence taught us? Am J Resp Crit Care. https://doi.org/10.1164/rccm.201810-1838TR
Sundbom F, Janson C, Malinovschi A, Lindberg E (2018) Effects of coexisting asthma and obstructive sleep apnea on sleep architecture, oxygen saturation, and systemic inflammation in women. J Clin Sleep Med 14(2):253–259
doi: 10.5664/jcsm.6946
Wang TY, Lo YL, Lin SM, Huang CD, Chung FT, Lin HC, Wang CH, Kuo HP (2017) Obstructive sleep apnoea accelerates FEV1 decline in asthmatic patients. BMC Pulm Med 17(1):55
doi: 10.1186/s12890-017-0398-2
Maislin G, Pack AI, Kribbs NB, Smith PL, Schwartz AR, Kline LR, Schwab RJ, Dinges DF (1995) A survey screen for prediction of apnea. Sleep. 18(3):158–166
doi: 10.1093/sleep/18.3.158
Fedson AC, Pack AI, Gislason T (2012) Frequently used sleep questionnaires in epidemiological and genetic research for obstructive sleep apnea: a review. Sleep Med Rev 16(6):529–537
doi: 10.1016/j.smrv.2011.12.002
Gislason T, Janson C, Vermeire P, Plaschke P, Bjornsson E, Gislason D et al (2002) Respiratory symptoms and nocturnal gastroesophageal reflux: a population-based study of young adults in three European countries. Chest. 121(1):158–163
doi: 10.1378/chest.121.1.158
Janson C, De Backer W, Gislason T, Plaschke P, Bjornsson E, Hetta J et al (1996) Increased prevalence of sleep disturbances and daytime sleepiness in subjects with bronchial asthma: a population study of young adults in three European countries. Eur Respir J 9(10):2132–2138
doi: 10.1183/09031936.96.09102132
Johannessen A, Verlato G, Benediktsdottir B, Forsberg B, Franklin K, Gislason T et al (2014) Longterm follow-up in European respiratory health studies—patterns and implications. BMC Pul Med 14:63
doi: 10.1186/1471-2466-14-63
Flexeder C, Zock JP, Jarvis D, Verlato G, Olivieri M, Benke G, Abramson MJ, Sigsgaard T, Svanes C, Torén K, Nowak D, Jõgi R, Martinez-Moratalla J, Demoly P, Janson C, Gislason T, Bono R, Holm M, Franklin KA, Garcia-Aymerich J, Siroux V, Leynaert B, Dorado Arenas S, Corsico AG, Pereira-Vega A, Probst-Hensch N, Urrutia Landa I, Schulz H, Heinrich J (2019) Second-hand smoke exposure in adulthood and lower respiratory health during 20 year follow up in the European Community Respiratory Health Survey. Respir Res 20(1):33
doi: 10.1186/s12931-019-0996-z
Chinn S, Jarvis D, Melotti R, Luczynska C, Ackermann-Liebrich U, Anto JM et al (2005) Smoking cessation, lung function, and weight gain: a follow-up study. Lancet. 365(9471):1629–1635 discussion 00-1
doi: 10.1016/S0140-6736(05)66511-7
Quanjer PH, Stanojevic S, Cole TJ, Baur X, Hall GL, Culver BH, Enright PL, Hankinson JL, Ip MSM, Zheng J, Stocks J, the ERS Global Lung Function Initiative (2012) Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations. Eur Respir J 40(6):1324–1343
doi: 10.1183/09031936.00080312
Thyagarajan B, Jacobs DR Jr, Apostol GG, Smith LJ, Jensen RL, Crapo RO, Barr RG, Lewis CE, Williams OD (2008) Longitudinal association of body mass index with lung function: the CARDIA study. Respir Res 9:31
doi: 10.1186/1465-9921-9-31
Zerah-Lancner F, Lofaso F, Coste A, Ricolfi F, Goldenberg F, Harf A (1997) Pulmonary function in obese snorers with or without sleep apnea syndrome. Am J Respir Crit Care Med 156(2 Pt 1):522–527
doi: 10.1164/ajrccm.156.2.9609015
Vandenbussche NL, Overeem S, van Dijk JP, Simons PJ, Pevernagie DA (2015) Assessment of respiratory effort during sleep: esophageal pressure versus noninvasive monitoring techniques. Sleep Med Rev 24:28–36
doi: 10.1016/j.smrv.2014.12.006
Lee SA, Amis TC, Byth K, Larcos G, Kairaitis K, Robinson TD, Wheatley JR (2008) Heavy snoring as a cause of carotid artery atherosclerosis. Sleep. 31(9):1207–1213
pubmed: 18788645
pmcid: 2542975
Bikov A, Losonczy G, Kunos L (2017) Role of lung volume and airway inflammation in obstructive sleep apnea. Respir Investig 55(6):326–333
doi: 10.1016/j.resinv.2017.08.009
Davies SE, Bishopp A, Wharton S, Turner AM, Mansur AH (2018) Does continuous positive airway pressure (CPAP) treatment of obstructive sleep apnoea (OSA) improve asthma-related clinical outcomes in patients with co-existing conditions?—a systematic review. Respir Med 143:18–30
doi: 10.1016/j.rmed.2018.08.004
Tam S, Woodson BT, Rotenberg B (2014) Outcome measurements in obstructive sleep apnea: beyond the apnea-hypopnea index. Laryngoscope. 124(1):337–343
doi: 10.1002/lary.24275
Ye L, Pien GW, Ratcliffe SJ, Björnsdottir E, Arnardottir ES, Pack AI, Benediktsdottir B, Gislason T (2014) The different clinical faces of obstructive sleep apnoea: a cluster analysis. Eur Respir J 44(6):1600–1607
doi: 10.1183/09031936.00032314
Mazzotti DR, Keenan BT, Lim DC, Gottlieb DJ, Kim J, Pack AI (2019) Symptom subtypes of obstructive sleep apnea predict incidence of cardiovascular outcomes. Am J Respir Crit Care Med 200(4):493–506
doi: 10.1164/rccm.201808-1509OC