Understanding Dynamics of Polymorphic Conversion during the Tableting Process Using

Chemistry, Pharmaceutical / methods Chlorpropamide / chemistry Drug Compounding / methods Hypoglycemic Agents / chemistry Powders / chemistry Pressure Spectrum Analysis, Raman / methods Tablets / chemistry X-Ray Diffraction / methods
chlorpropamide deformation in situ mechanical Raman spectroscopy polymorphic interconversion tableting

Journal

Molecular pharmaceutics
ISSN: 1543-8392
Titre abrégé: Mol Pharm
Pays: United States
ID NLM: 101197791

Informations de publication

Date de publication:
03 08 2020
Historique:
pubmed: 8 7 2020
medline: 29 6 2021
entrez: 8 7 2020
Statut: ppublish

Résumé

The objective of this study is to achieve a fundamental understanding of polymorphic interconversion during the tableting process, including during compaction, dwell, decompression/unloading, and ejection using an

Identifiants

DOI: 10.1021/acs.molpharmaceut.0c00460 PMID: 32633984
pubmed: 32633984
doi: 10.1021/acs.molpharmaceut.0c00460
doi:

Substances chimiques

Hypoglycemic Agents 0
Powders 0
Tablets 0
Chlorpropamide WTM2C3IL2X

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3043-3052

Auteurs

Heejun Park (H)

Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, 575 Stadium Mall Drive, West Lafayette, Indiana 47907, United States.

Haichen Nie (H)

Oral Formulation Sciences, Pharmaceutical Sciences, Merck & Co., Inc., 126 E. Lincoln Avenue, Rahway, New Jersey 07065, United States.

Abhijeet Dhiman (A)

School of Aeronautics and Astronautics, Purdue University, 575 Stadium Mall Drive, West Lafayette, Indiana 47907, United States.

Vikas Tomar (V)

School of Aeronautics and Astronautics, Purdue University, 575 Stadium Mall Drive, West Lafayette, Indiana 47907, United States.

Qi Tony Zhou (QT)

Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, 575 Stadium Mall Drive, West Lafayette, Indiana 47907, United States.
ORCID: 0000-0002-1438-6990

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Classifications MeSH

questionsmedicales.fr › Disciplines des sciences naturelles › Chimie › Chimie pharmaceutique › Understanding Dynamics of Polymorphic...
questionsmedicales.fr › Composés chimiques organiques › Composés du soufre › Sulfones › Sulfonylurées › Chlorpropamide › Understanding Dynamics of Polymorphic...
questionsmedicales.fr › Techniques d'investigation › Préparation de médicament › Understanding Dynamics of Polymorphic...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Hypoglycémiants › Understanding Dynamics of Polymorphic...
questionsmedicales.fr › Préparations pharmaceutiques › Poudres › Understanding Dynamics of Polymorphic...
questionsmedicales.fr › Phénomènes physiques › Phénomènes mécaniques › Pression › Understanding Dynamics of Polymorphic...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Analyse spectrale Raman › Understanding Dynamics of Polymorphic...
questionsmedicales.fr › Préparations pharmaceutiques › Comprimés › Understanding Dynamics of Polymorphic...
questionsmedicales.fr › Phénomènes chimiques › Diffraction des rayons X › Understanding Dynamics of Polymorphic...