IMPACT-Scot report on COVID-19 and hip fractures.
Aged
Aged, 80 and over
COVID-19
COVID-19 Testing
Cause of Death
Clinical Laboratory Techniques
Cohort Studies
Coronavirus Infections
/ diagnosis
Female
Hip Fractures
/ diagnosis
Hospital Mortality
Humans
Incidence
Male
Pandemics
Pneumonia, Viral
/ diagnosis
Predictive Value of Tests
Proportional Hazards Models
Reference Values
Retrospective Studies
Risk Assessment
Survival Rate
Trauma Centers
COVID-19
Coronavirus
Femoral neck fracture
Hip fracture
Mortality
Neck of femur fracture
Outcomes
Platelets
Predictors
SARS-CoV-2
Journal
The bone & joint journal
ISSN: 2049-4408
Titre abrégé: Bone Joint J
Pays: England
ID NLM: 101599229
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
pubmed:
8
7
2020
medline:
9
9
2020
entrez:
8
7
2020
Statut:
ppublish
Résumé
The primary aim was to assess the independent influence of coronavirus disease (COVID-19) on 30-day mortality for patients with a hip fracture. The secondary aims were to determine whether: 1) there were clinical predictors of COVID-19 status; and 2) whether social lockdown influenced the incidence and epidemiology of hip fractures. A national multicentre retrospective study was conducted of all patients presenting to six trauma centres or units with a hip fracture over a 46-day period (23 days pre- and 23 days post-lockdown). Patient demographics, type of residence, place of injury, presentation blood tests, Nottingham Hip Fracture Score, time to surgery, operation, American Society of Anesthesiologists (ASA) grade, anaesthetic, length of stay, COVID-19 status, and 30-day mortality were recorded. Of 317 patients with acute hip fracture, 27 (8.5%) had a positive COVID-19 test. Only seven (26%) had suggestive symptoms on admission. COVID-19-positive patients had a significantly lower 30-day survival compared to those without COVID-19 (64.5%, 95% confidence interval (CI) 45.7 to 83.3 vs 91.7%, 95% CI 88.2 to 94.8; p < 0.001). COVID-19 was independently associated with increased 30-day mortality risk adjusting for: 1) age, sex, type of residence (hazard ratio (HR) 2.93; p = 0.008); 2) Nottingham Hip Fracture Score (HR 3.52; p = 0.001); and 3) ASA (HR 3.45; p = 0.004). Presentation platelet count predicted subsequent COVID-19 status; a value of < 217 × 10 COVID-19 was independently associated with an increased 30-day mortality rate for patients with a hip fracture. Notably, most patients with hip fracture and COVID-19 lacked suggestive symptoms at presentation. Platelet count was an indicator of risk of COVID-19 infection. These findings have implications for the management of hip fractures, in particular the need for COVID-19 testing. Cite this article:
Identifiants
pubmed: 32634029
doi: 10.1302/0301-620X.102B9.BJJ-2020-1100.R1
doi:
Types de publication
Comparative Study
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
1219-1228Investigateurs
Jonathan Antrobus
(J)
Stuart Baird
(S)
James A Ballantyne
(JA)
Jean Bell
(J)
Caitlin Brennan
(C)
Lucy Campbell
(L)
Carol Carnegie
(C)
Alastair W Murray
(AW)
James T Patton
(JT)
Matilda Powell-Bowns
(M)
Dylan Jun Hao Tan
(D)
Thisara Weerasuriya
(T)
Janet Wood
(J)
Commentaires et corrections
Type : CommentIn