IMPACT-Scot report on COVID-19 and hip fractures.


Journal

The bone & joint journal
ISSN: 2049-4408
Titre abrégé: Bone Joint J
Pays: England
ID NLM: 101599229

Informations de publication

Date de publication:
09 2020
Historique:
pubmed: 8 7 2020
medline: 9 9 2020
entrez: 8 7 2020
Statut: ppublish

Résumé

The primary aim was to assess the independent influence of coronavirus disease (COVID-19) on 30-day mortality for patients with a hip fracture. The secondary aims were to determine whether: 1) there were clinical predictors of COVID-19 status; and 2) whether social lockdown influenced the incidence and epidemiology of hip fractures. A national multicentre retrospective study was conducted of all patients presenting to six trauma centres or units with a hip fracture over a 46-day period (23 days pre- and 23 days post-lockdown). Patient demographics, type of residence, place of injury, presentation blood tests, Nottingham Hip Fracture Score, time to surgery, operation, American Society of Anesthesiologists (ASA) grade, anaesthetic, length of stay, COVID-19 status, and 30-day mortality were recorded. Of 317 patients with acute hip fracture, 27 (8.5%) had a positive COVID-19 test. Only seven (26%) had suggestive symptoms on admission. COVID-19-positive patients had a significantly lower 30-day survival compared to those without COVID-19 (64.5%, 95% confidence interval (CI) 45.7 to 83.3 vs 91.7%, 95% CI 88.2 to 94.8; p < 0.001). COVID-19 was independently associated with increased 30-day mortality risk adjusting for: 1) age, sex, type of residence (hazard ratio (HR) 2.93; p = 0.008); 2) Nottingham Hip Fracture Score (HR 3.52; p = 0.001); and 3) ASA (HR 3.45; p = 0.004). Presentation platelet count predicted subsequent COVID-19 status; a value of < 217 × 10 COVID-19 was independently associated with an increased 30-day mortality rate for patients with a hip fracture. Notably, most patients with hip fracture and COVID-19 lacked suggestive symptoms at presentation. Platelet count was an indicator of risk of COVID-19 infection. These findings have implications for the management of hip fractures, in particular the need for COVID-19 testing. Cite this article:

Identifiants

pubmed: 32634029
doi: 10.1302/0301-620X.102B9.BJJ-2020-1100.R1
doi:

Types de publication

Comparative Study Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

1219-1228

Investigateurs

Jonathan Antrobus (J)
Stuart Baird (S)
James A Ballantyne (JA)
Jean Bell (J)
Caitlin Brennan (C)
Lucy Campbell (L)
Carol Carnegie (C)
Alastair W Murray (AW)
James T Patton (JT)
Matilda Powell-Bowns (M)
Dylan Jun Hao Tan (D)
Thisara Weerasuriya (T)
Janet Wood (J)

Commentaires et corrections

Type : CommentIn

Auteurs

Andrew J Hall (AJ)

Edinburgh Orthopaedics, Royal Infirmary of Edinburgh, Edinburgh, UK.
Scottish Orthopaedic Research Trust into Trauma (SORT-IT), Edinburgh, UK.
Scottish Hip Fracture Audit (SHFA), NHS National Services Scotland, UK.

Nicholas D Clement (ND)

Edinburgh Orthopaedics, Royal Infirmary of Edinburgh, Edinburgh, UK.
Scottish Orthopaedic Research Trust into Trauma (SORT-IT), Edinburgh, UK.

Luke Farrow (L)

Scottish Hip Fracture Audit (SHFA), NHS National Services Scotland, UK.
University of Aberdeen, Aberdeen, UK.

Alasdair M J MacLullich (AMJ)

Edinburgh Orthopaedics, Royal Infirmary of Edinburgh, Edinburgh, UK.
Geriatric Medicine, Usher Institute, University of Edinburgh, Edinburgh, UK.

Graham F Dall (GF)

Borders General Hospital, Melrose, UK.

Chloe E H Scott (CEH)

Edinburgh Orthopaedics, Royal Infirmary of Edinburgh, Edinburgh, UK.
Department of Orthopaedics and Trauma, University of Edinburgh, Edinburgh, UK.

Paul J Jenkins (PJ)

Scottish Orthopaedic Research Trust into Trauma (SORT-IT), Edinburgh, UK.
Glasgow Royal Infirmary, Glasgow, UK.
Scottish Committee for Orthopaedics & Trauma, Edinburgh, UK.

Timothy O White (TO)

Edinburgh Orthopaedics, Royal Infirmary of Edinburgh, Edinburgh, UK.
Scottish Orthopaedic Research Trust into Trauma (SORT-IT), Edinburgh, UK.

Andrew D Duckworth (AD)

Edinburgh Orthopaedics, Royal Infirmary of Edinburgh, Edinburgh, UK.
Scottish Orthopaedic Research Trust into Trauma (SORT-IT), Edinburgh, UK.
Department of Orthopaedics and Trauma, University of Edinburgh, Edinburgh, UK.

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