Confirmed Invasive Pulmonary Aspergillosis and COVID-19: the value of postmortem findings to support antemortem management.
Journal
Revista da Sociedade Brasileira de Medicina Tropical
ISSN: 1678-9849
Titre abrégé: Rev Soc Bras Med Trop
Pays: Brazil
ID NLM: 7507456
Informations de publication
Date de publication:
2020
2020
Historique:
received:
22
06
2020
accepted:
26
06
2020
entrez:
9
7
2020
pubmed:
9
7
2020
medline:
17
7
2020
Statut:
ppublish
Résumé
We present postmortem evidence of invasive pulmonary aspergillosis (IPA) in a patient with severe COVID-19. Autopsies of COVID-19 confirmed cases were performed. The patient died despite antimicrobials, mechanical ventilation, and vasopressor support. Histopathology and peripheral blood galactomannan antigen testing confirmed IPA. Aspergillus penicillioides infection was confirmed by nucleotide sequencing and BLAST analysis. Further reports are needed to assess the occurrence and frequency of IPA in SARS-CoV-2 infections, and how they interact clinically.
Identifiants
pubmed: 32638890
pii: S0037-86822020000100719
doi: 10.1590/0037-8682-0401-2020
pmc: PMC7341831
pii:
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e20200401Références
Travel Med Infect Dis. 2020 May 26;:101752
pubmed: 32470620
N Engl J Med. 2003 Jul 31;349(5):507-8
pubmed: 12890854
Lancet. 2020 Mar 28;395(10229):1054-1062
pubmed: 32171076
Pediatr Dev Pathol. 2016 Nov/Dec;19(6):506-511
pubmed: 26579953
Lancet Respir Med. 2018 Oct;6(10):782-792
pubmed: 30076119
J Clin Microbiol. 2010 Jun;48(6):2147-53
pubmed: 20392915
J Infect Dis. 2013 Jun 15;207(12):1932-9
pubmed: 23482646
Antiviral Res. 2018 Feb;150:202-216
pubmed: 29325970
Curr Opin Infect Dis. 2018 Dec;31(6):471-480
pubmed: 30299367
Pol J Microbiol. 2018;67(4):407-416
pubmed: 30550227
J Bronchology Interv Pulmonol. 2020 Mar 18;:
pubmed: 32195687
Emerg Infect Dis. 2020 Jul;26(7):1636-1637
pubmed: 32343223
Med Mycol Case Rep. 2019 Sep 25;26:25-27
pubmed: 31667056
J Adv Nurs. 2017 Nov;73(11):2522-2533
pubmed: 28440960