Cancers of the corpus uteri treated in South Australian public hospitals: Trends in clinical management and survival across three decades.
cancer
chemotherapy
management
radiotherapy
staging
surgery
Journal
European journal of cancer care
ISSN: 1365-2354
Titre abrégé: Eur J Cancer Care (Engl)
Pays: England
ID NLM: 9301979
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
received:
17
02
2020
accepted:
05
06
2020
pubmed:
9
7
2020
medline:
30
9
2021
entrez:
9
7
2020
Statut:
ppublish
Résumé
To investigate treatment and survival over three decades. Clinical registry data from three major public hospitals analysed using Kaplan-Meier product-limit estimates and multivariate proportional hazard regression to determine disease-specific survival. Five-year survival increased from 75% to 84%. The adjusted hazard ratio (HR, 95% CI) was 0.56 (0.41, 0.77) for 2010-2016 compared with 1984-1989 and was higher for: ages 80+ years; more advanced stages; poorly differentiated tumours; and complex mixed epithelial and mesenchymal tumours and sarcomas. Treatment was by surgery (92%), radiotherapy (33%), chemotherapy (12%) and hormone therapy (10%). Adjusted analyses showed radiotherapy and hormone therapy were less common from 1990 and chemotherapy more common for 2010-2016. Treatment likelihood was lower for ages ≥80 years, mixed epithelial and mesenchymal tumours receiving surgery and chemotherapy, but higher for radiotherapy. Advanced cancers (FIGO stage IV) had less surgery but more non-surgical treatments. Marginal evidence presented of more hormone therapy for high socio-economic areas. Survival was equivalent to national figures for Australia and the United States, but potentially higher than for England and Wales. Cases aged 80+ years had less care and poorer survival. Findings illustrate the complementary roles of hospital and population-based registries in local service evaluation.
Types de publication
Journal Article
Langues
eng
Pagination
e13281Subventions
Organisme : Cancer Council South Australia: Beat Cancer Project
Informations de copyright
© 2020 John Wiley & Sons Ltd.
Références
American College of Surgeons. (2016). Facility Oncology Registry Standards (FORDS): Revised for 2016. Chicago, IL: American College of Surgeons.
Arem, H., & Irwin, M. L. (2013). Obesity and endometrial cancer survival: A systematic review. International Journal of Obstetrics (London), 37(5), 634-639. https://doi.org/10.1038/ijo.2012.94
Armitage, P., Berry, G., & Mathews, J. N. S. (1987). Statistical methods in medical research (2nd edn). Oxford, UK: Blackwell Scientific Publications. https://doi.org/10.1002/sim.4780070711
Australian Bureau of Statistics. (2018). Socio-Economic indexes for areas. Canberra: ABS. Retrieved from https://www.abs.gov.au/websitedbs/censushome.nsf/home/seifa
Australian Institute of Health and Welfare (AIHW). (2008). Cancer Australia and Australasian Association of Cancer Registries. Cancer survival and prevalence in Australia: cancers diagnosed from 1982 to 2004. Cancer Series no. 42. Cat. No. CAN 38. Canberra: AIHW.
Australian Institute of Health and Welfare (AIHW). (2017a). Cancer in Australia 2017. Cancer series no. 101. Cat. no. CAN 100. Canberra: AIHW.
Australian Institute of Health and Welfare (AIHW). (2017b). Australian Cancer Incidence and Mortality (ACIM) books. Canberra: AIHW. Retrieved from http://www.aihw.gov.au/acim-books/
Australian Institute of Health and Welfare (AIHW). (2019). Cancer in Australia 2019. Cancer series no. 119. Cat. no. CAN 123. Canberra: AIHW.
Bonett, A., Roder, D., & Esterman, A. (1988). Cancer case-survival rates for South Australia: A comparison with US rates and a preliminary investigation of time trends. Medical Journal of Australia, 148(11), 556-559. https://doi.org/10.5694/j.1326-5377.1988.tb93810.x
Calle, E. E., Rodriguez, C., Walker-Thurmond, K., & Thun, M. J. (2003). Overweight, obesity, and mortality from cancer in a prospectively studied cohort of US adults. The New England Journal of Medicine, 348(17), 1625-1638. https://doi.org/10.1056/NEJMoa021423
Cancer Research UK. (2018). Uterine cancer risk. London: Cancer Research UK. Retrieved from https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/uterine-cancer/risk-factors
Fine, J. P., & Gray, R. J. (1999). A proportional hazards model for subdistribution of a competing risk. Journal of the American Statistical Association, 94(446), 496-509. https://doi.org/10.1080/01621459.1999.10474144
Fritz, A., C. Percy, A. Jack, K. Shanmugaratnam, L. Sobin, D. M. Parkin, & S. Whelan (eds.) (2000). International classification of diseases for oncology: ICD-0 (3rd edn). Geneva: World Health Organization.
Government of South Australia. (2017). South Australia: Health Care Act 2008 - Part 7. Version: 5.6.2017. Adelaide: South Australian Government.
Noone, A. M., Howlader, N., Krapcho, M., Miller, D., Brest, A., Yu, M., Cronin, K. A. (eds) (2018). SEER cancer statistics review, 1975-2015. Bethesda, MD: National Cancer Institute. Retrieved from https://seer.cancer.gov/csr/1975_2015/
Pecorelli, S. (2009). Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium. International Journal of Gynecology & Obstetrics, 105(2), 103-104. https://doi.org/10.1016/j.ijgo.2009.02.012
Roder, D., Karapetis, C. S., Wattchow, D., Moore, J., Singhal, N., Joshi, R., … Price, T. J. (2015). Colorectal cancer treatment and survival: The experience of major public hospitals in South Australia over three decades. Asian Pacific Journal of Cancer Prevention, 16(6), 2431-2440. https://doi.org/10.7314/APJCP.2015.16.6.2431
Roulson, J. A., Benbow, E. W., & Hasleton, P. S. (2005). Discrepancies between clinical and autopsy diagnosis and the value of post mortem histology; a meta-analysis and review. Histopathology, 47(6), 551-559. https://doi.org/10.1111/j.1365-2559.2005.02243.x
South Australian Cancer Registry. (1997). Epidemiology of cancer in South Australia. Incidence, mortality and survival 1977 to 1996. Issue 19, Cancer Series. Adelaide: South Australian Department of Health.
South Australian Cancer Registry. (2000). Epidemiology of cancer in South Australia. Incidence, mortality and survival 1977 to 1999. Issue 22, Cancer Series. Adelaide: South Australian Department of Health.
South Australian Cancer Registry. (2007). Cancer in South Australia 2004 with incidence projections to 2007. Adelaide: South Australian Cancer Registry.
StataCorp. (2018). Stata statistical software. Release 16. College Station, TX: StataCorp LP.
Yost, K. J., Cheville, A. L., Al-Hilli, M. M., Mariani, A., Barrette, B. A., McGree, M. E., … Dowdy, S. C. (2014). Lymphedema after surgery for endometrial cancer: Prevalence, risk factors, and quality of life. Obstetrics and Gynecology, 124(201), 307-315. https://doi.org/10.1097/AOG.0000000000000372