Epitope Mapping of DhMab-1: An Antidiacylglycerol Kinase Monoclonal Antibody.
DGKh
DhMab-1
monoclonal antibody
Journal
Monoclonal antibodies in immunodiagnosis and immunotherapy
ISSN: 2167-9436
Titre abrégé: Monoclon Antib Immunodiagn Immunother
Pays: United States
ID NLM: 101590955
Informations de publication
Date de publication:
Aug 2020
Aug 2020
Historique:
pubmed:
10
7
2020
medline:
25
6
2021
entrez:
10
7
2020
Statut:
ppublish
Résumé
Diacylglycerol kinase (DGK) η is classified as a type II DGK and catalyzes diacylglycerol phosphorylation to produce phosphatidic acid. DGKη has been reported to be highly expressed in the hippocampus and cerebellum. Although a DGKη-specific monoclonal antibody (mAb) is necessary to reveal the association between the expression of DGKη and diseases, an anti-DGKη mAb for immunohistochemistry has not been developed. Recently, we established a specific antihuman DGKη (hDGKη) mAb, DhMab-1 (mouse IgG
Identifiants
pubmed: 32640865
doi: 10.1089/mab.2020.0014
doi:
Substances chimiques
Antibodies, Monoclonal
0
Epitopes
0
DGKH protein, human
EC 2.7.1.107
Diacylglycerol Kinase
EC 2.7.1.107
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM