Characterization of humoral and cellular immune features of gamma-irradiated influenza vaccine.
Influenza A virus
dendritic cells
gamma-irradiation
mucosal immunity
whole cell inactivated vaccine
Journal
Human vaccines & immunotherapeutics
ISSN: 2164-554X
Titre abrégé: Hum Vaccin Immunother
Pays: United States
ID NLM: 101572652
Informations de publication
Date de publication:
01 02 2021
01 02 2021
Historique:
pubmed:
10
7
2020
medline:
23
6
2021
entrez:
10
7
2020
Statut:
ppublish
Résumé
The most widely used influenza vaccines are prepared by chemical inactivation. However, chemical, especially formalin, treatment-induced modifications of the antigenic structure of the virus are frequently associated with adverse effects including low efficacy of protection, unexpected immune responses, or exacerbation of disease. Gamma-irradiation was suggested as an alternative influenza virus inactivation method due to its great features of completely inactivating virus while not damaging the structures of protein antigens, and cross-protective ability against heterologous strains. However, immunological features of gamma radiation-inactivated influenza vaccine have not been fully understood. In this study, we aimed to investigate the humoral and cellular immune responses of gamma radiation-inactivated influenza vaccine. The gamma irradiation-inactivated influenza vaccine (RADVAX
Identifiants
pubmed: 32643515
doi: 10.1080/21645515.2020.1780091
pmc: PMC7899634
doi:
Substances chimiques
Antibodies, Viral
0
Influenza Vaccines
0
Vaccines, Inactivated
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
485-496Références
Vaccine. 2003 Jul 4;21(23):3212-8
pubmed: 12804850
Nat Med. 2012 Jun;18(6):974-9
pubmed: 22635006
J Immunol. 1983 Dec;131(6):2895-902
pubmed: 6358356
Science. 1993 Mar 19;259(5102):1745-9
pubmed: 8456302
Immunity. 2006 Jul;25(1):143-52
pubmed: 16860763
Front Immunol. 2014 Apr 23;5:182
pubmed: 24795724
Immunol Cell Biol. 2012 Jul;90(6):571-8
pubmed: 21844883
J Exp Med. 1987 Feb 1;165(2):408-16
pubmed: 3029268
Jpn J Infect Dis. 2004 Dec;57(6):236-47
pubmed: 15623947
J Oral Maxillofac Pathol. 2012 Sep;16(3):400-5
pubmed: 23248474
PLoS One. 2009;4(4):e5336
pubmed: 19401775
PLoS One. 2013;8(2):e56164
pubmed: 23424649
Infect Immun. 2009 Apr;77(4):1649-63
pubmed: 19168734
Curr Opin Virol. 2016 Apr;17:95-103
pubmed: 26927813
Front Immunol. 2015 May 15;6:237
pubmed: 26029218
Curr Opin Immunol. 1999 Feb;11(1):89-93
pubmed: 10047532
Retrovirology. 2016 Nov 28;13(1):82
pubmed: 27894306
Cell. 2001 Aug 10;106(3):263-6
pubmed: 11509174
Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):540-5
pubmed: 19122146
Hum Vaccin Immunother. 2012 Jan;8(1):89-95
pubmed: 22251992
Infect Immun. 2009 Nov;77(11):5181-9
pubmed: 19703982
Vaccine. 2019 Mar 14;37(12):1630-1637
pubmed: 30765167
Vaccine. 2002 May 15;20 Suppl 2:S5-14
pubmed: 12110248
Vaccine. 2018 Feb 8;36(7):997-1007
pubmed: 29373192
Vaccine. 2017 Sep 18;35(39):5297-5302
pubmed: 28780981
Infect Immun. 1974 Dec;10(6):1329-36
pubmed: 4435958
Clin Exp Immunol. 2013 Feb;171(2):147-54
pubmed: 23286941
Nat Med. 2005 Aug;11(8):853-60
pubmed: 16041382
Vaccine. 2017 Feb 15;35(7):1071-1079
pubmed: 28109709
Front Microbiol. 2017 Dec 12;8:2469
pubmed: 29312180
Mol Immunol. 2018 Sep;101:344-352
pubmed: 30036800
PLoS One. 2016 Mar 09;11(3):e0150700
pubmed: 26959983
J Clin Microbiol. 1978 Oct;8(4):431-4
pubmed: 721947
Front Microbiol. 2017 May 17;8:900
pubmed: 28567036
J Infect Dis. 2015 Dec 15;212(12):1914-22
pubmed: 26014800
Vaccine. 2016 Jun 3;34(26):2926-2933
pubmed: 27038130
Eur Respir J. 2001 Sep;18(3):571-88
pubmed: 11589357
JAMA. 1994 Dec 7;272(21):1661-5
pubmed: 7966893
Vaccine. 2010 Jan 22;28(4):1031-40
pubmed: 19914193
Clin Sci (Lond). 2017 Jan 1;131(2):169-180
pubmed: 27885052
J Gen Virol. 2010 Jun;91(Pt 6):1450-60
pubmed: 20147516
Immunol Cell Biol. 1988 Apr;66 ( Pt 2):153-7
pubmed: 2846435
Curr Opin Biotechnol. 2012 Dec;23(6):917-23
pubmed: 22608846
Vox Sang. 2003 Jan;84(1):36-44
pubmed: 12542732
Am Rev Respir Dis. 1981 Dec;124(6):681-4
pubmed: 7316272
Blood. 2012 Jun 14;119(24):5640-9
pubmed: 22535666
PLoS Negl Trop Dis. 2015 Oct 23;9(10):e0004167
pubmed: 26495991
Appl Microbiol. 1971 Apr;21(4):688-92
pubmed: 5575570
Glob Heart. 2014 Sep;9(3):325-36
pubmed: 25667184
Chest. 2013 Feb 1;143(2):502-510
pubmed: 23381315
Clin Exp Vaccine Res. 2015 Jul;4(2):145-58
pubmed: 26273573
Immunity. 2002 Mar;16(3):379-89
pubmed: 11911823
Nat Med. 2006 Aug;12(8):905-7
pubmed: 16862151
J Gen Virol. 1989 Sep;70 ( Pt 9):2439-48
pubmed: 2778440
Am J Epidemiol. 1976 Jul;104(1):34-46
pubmed: 947145
Vaccine. 1989 Aug;7(4):303-8
pubmed: 2815966
J Immunol. 2004 Aug 1;173(3):1978-86
pubmed: 15265932
Sci Rep. 2015 Dec 01;5:17214
pubmed: 26621769
PLoS One. 2011 Jan 18;6(1):e14538
pubmed: 21267073
Appl Microbiol. 1970 May;19(5):763-7
pubmed: 5463575
J Virol. 1998 Jul;72(7):5648-53
pubmed: 9621023
Clin Vaccine Immunol. 2006 Sep;13(9):981-90
pubmed: 16960108