Hypofractionated Whole Breast Irradiation and Simultaneous Integrated Boost in Large-breasted Patients: Long-term Toxicity and Cosmesis.
Adult
Aged
Aged, 80 and over
Breast
/ abnormalities
Breast Neoplasms
/ complications
Dose-Response Relationship, Radiation
Esthetics
Feasibility Studies
Female
Follow-Up Studies
Humans
Hypertrophy
/ complications
Middle Aged
Organ Size
Radiation Dose Hypofractionation
Radiodermatitis
/ epidemiology
Radiometry
/ statistics & numerical data
Radiotherapy, Adjuvant
/ adverse effects
Radiotherapy, Intensity-Modulated
/ adverse effects
Retrospective Studies
Skin
/ pathology
Time Factors
Treatment Outcome
Young Adult
Breast size
Hypofractionation
Late toxicity
SIB
VMAT
Journal
Clinical breast cancer
ISSN: 1938-0666
Titre abrégé: Clin Breast Cancer
Pays: United States
ID NLM: 100898731
Informations de publication
Date de publication:
12 2020
12 2020
Historique:
received:
08
02
2020
revised:
03
06
2020
accepted:
12
06
2020
pubmed:
16
7
2020
medline:
12
10
2021
entrez:
16
7
2020
Statut:
ppublish
Résumé
The purpose of this study was to evaluate the impact of breast size on long-term toxicity and cosmesis in patients with breast cancer treated with hypofractionated simultaneous integrated boost (SIB) using volumetric modulated arc therapy (VMAT). Patients with early stage breast cancer were treated with 3-week hypofractionated SIB-VMAT to the whole breast (40.5 Gy) and tumor bed (48 Gy). Two cohorts were identified: small/medium- (< 1000 cm From August 2010 to March 2017, a total of 1160 patients were treated; 831 had at least 2 years of follow-up and were analyzed. Treated skin area (TSA) receiving at least 20 Gy > 400 cm The TSA > 400 cm
Identifiants
pubmed: 32665192
pii: S1526-8209(20)30149-X
doi: 10.1016/j.clbc.2020.06.005
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
527-533Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.