Obesity and pituitary gland volume - a correlation study using three-dimensional magnetic resonance imaging.
Adolescent
Adult
Age Factors
Aged
Body Mass Index
Contrast Media
Female
Humans
Imaging, Three-Dimensional
/ methods
Magnetic Resonance Imaging
/ methods
Male
Middle Aged
Obesity
/ complications
Organ Size
Organometallic Compounds
Pituitary Gland
/ diagnostic imaging
Retrospective Studies
Sex Factors
Magnetic resonance imaging
body mass index
obesity
pituitary gland volume
Journal
The neuroradiology journal
ISSN: 2385-1996
Titre abrégé: Neuroradiol J
Pays: United States
ID NLM: 101295103
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
pubmed:
16
7
2020
medline:
8
6
2021
entrez:
16
7
2020
Statut:
ppublish
Résumé
Obesity has become a major health problem and is associated with endocrine disorders and a disturbed hypothalamic-pituitary axis. The purpose of this study was to correlate pituitary gland volume determined by routine magnetic resonance imaging with patient characteristics, in particular body mass index and obesity. A total of 144 'healthy' patients with normal findings in cerebral magnetic resonance imaging were retrospectively included. Pituitary gland volume was measured in postcontrast three-dimensional T1-weighted sequences. A polygonal three-dimensional region of interest covering the whole pituitary gland was assessed manually. Physical characteristics (gender, age, body height and body mass index) were correlated with pituitary gland volume. Multiple subgroup and regression analyses were performed. Pituitary gland volumes were significantly larger in females than in males ( Pituitary gland volume is increased in obese individuals and a high body mass index can be seen as an independent predictor of increased pituitary gland volume. Therefore, gland enlargement might be an imaging indicator of dysfunction in the hypothalamus-pituitary axis. Besides gender and age, body mass index should be considered by radiologists when diagnosing abnormal changes in pituitary gland volume.
Identifiants
pubmed: 32666872
doi: 10.1177/1971400920937843
pmc: PMC7482044
doi:
Substances chimiques
Contrast Media
0
Organometallic Compounds
0
gadobutrol
1BJ477IO2L
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
400-409Références
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