Uncovering a novel molecular mechanism for scavenging sialic acids in bacteria.

2,7-anhydro-Neu5AC 2,7-anhydro-Neu5Ac Escherichia coli Escherichia coli (E. coli) Ruminococcus gnavus STD NMR gut microbiota gut symbiosis microbiology mucin glycosylation nuclear magnetic resonance (NMR) oxidation-reduction (redox) oxidoreductase sialic acid sialic acid transporters symbiosis

Journal

The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R

Informations de publication

Date de publication:
02 10 2020
Historique:
received: 31 05 2020
revised: 10 07 2020
pubmed: 17 7 2020
medline: 4 2 2021
entrez: 17 7 2020
Statut: ppublish

Résumé

The human gut symbiont

Identifiants

pubmed: 32669363
pii: S0021-9258(17)49824-3
doi: 10.1074/jbc.RA120.014454
pmc: PMC7535918
pii:
doi:

Substances chimiques

Bacterial Proteins 0
Mucins 0
Oxidoreductases EC 1.-
N-Acetylneuraminic Acid GZP2782OP0

Banques de données

PDB
['5UI9']

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

13724-13736

Subventions

Organisme : Biotechnology and Biological Sciences Research Council
ID : BBS/E/F/00044452
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/M011216/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/P008895/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/R012490/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/P010660/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BBS/E/F/000PR10353
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/C509807/1
Pays : United Kingdom

Informations de copyright

© 2020 Bell et al.

Déclaration de conflit d'intérêts

Conflict of interest—The authors declare that they have no conflicts of interest with the contents of this article.

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Auteurs

Andrew Bell (A)

Gut Microbes and Health Institute Strategic Programme, Quadram Institute Bioscience, Norwich, United Kingdom.

Emmanuele Severi (E)

Department of Biology, University of York, York, United Kingdom.

Micah Lee (M)

Division of Structural Biology, University of Oxford, Headington, Oxford, United Kingdom.

Serena Monaco (S)

School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, United Kingdom.

Dimitrios Latousakis (D)

Gut Microbes and Health Institute Strategic Programme, Quadram Institute Bioscience, Norwich, United Kingdom.

Jesus Angulo (J)

School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, United Kingdom; Departamento de Química Orgánica, Universidad de Sevilla, Sevilla, Spain; Instituto de Investigaciones Químicas (CSIC-US), Sevilla, Spain.

Gavin H Thomas (GH)

Department of Biology, University of York, York, United Kingdom.

James H Naismith (JH)

Division of Structural Biology, University of Oxford, Headington, Oxford, United Kingdom.

Nathalie Juge (N)

Gut Microbes and Health Institute Strategic Programme, Quadram Institute Bioscience, Norwich, United Kingdom. Electronic address: nathalie.juge@quadram.ac.uk.

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Classifications MeSH