Regulation of ABA-Non-Activated SNF1-Related Protein Kinase 2 Signaling Pathways by Phosphatidic Acid.
Arabidopsis thaliana
ERD14
PA
PP2CA
SCS
SNF1-related protein kinases
SnRK2
SnRK2-interacting calcium sensor
dehydrins
phosphatidic acid
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
15 Jul 2020
15 Jul 2020
Historique:
received:
16
06
2020
revised:
09
07
2020
accepted:
12
07
2020
entrez:
19
7
2020
pubmed:
19
7
2020
medline:
20
2
2021
Statut:
epublish
Résumé
Phosphatidic acid (PA) is involved in the regulation of plant growth and development, as well as responses to various environmental stimuli. Several PA targets in plant cells were identified, including two SNF1-related protein kinases 2 (SnRK2s), SnRK2.10 and SnRK2.4, which are not activated by abscisic acid (ABA). Here, we investigated the effects of PA on various elements of ABA-non-activated SnRK2 signaling. PA 16:0/18:1 was found to modulate the SnRK2 structure and the phosphorylation of some SnRK2 targets. Conversely, phosphorylation by the ABA-non-activated SnRK2s, of one of such targets, dehydrin Early Responsive to Dehydration 14 (ERD14), affects its interaction with PA and subcellular localization. Moreover, PA 16:0/18:1 modulates the activity and/or localization of negative regulators of the ABA-non-activated SnRK2s, not only of the ABA insensitive 1 (ABI1) phosphatase, which was identified earlier, but also of another protein phosphatase 2C, PP2CA. The activity of both phosphatases was inhibited by about 50% in the presence of 50 μM PA. PA 16:0/18:1 also impacts the phosphorylation and subcellular localization of SnRK2-interacting calcium sensor, known to inhibit SnRK2 activity in a calcium-dependent manner. Thus, PA was found to regulate ABA-non-activated SnRK2 signaling at several levels: the activity, phosphorylation status and/or localization of SnRK2 cellular partners.
Identifiants
pubmed: 32679718
pii: ijms21144984
doi: 10.3390/ijms21144984
pmc: PMC7404309
pii:
doi:
Substances chimiques
Arabidopsis Proteins
0
Phosphatidic Acids
0
SnRK2 protein, Arabidopsis
0
Abscisic Acid
72S9A8J5GW
Protein Serine-Threonine Kinases
EC 2.7.11.1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Narodowe Centrum Nauki
ID : 2011/03/B/NZ3/00297 and 2016/23/B/NZ3/03182
Organisme : Norwegian Research Council and the Research Program of the EEA/Norway Grants
ID : PolNor/203156/70/2013
Références
Plant Cell. 2013 Dec;25(12):5030-42
pubmed: 24368785
J Biol Chem. 2011 Feb 4;286(5):3429-41
pubmed: 21098029
Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17588-93
pubmed: 19805022
J Exp Bot. 2011 Apr;62(7):2349-61
pubmed: 21430291
Sci Signal. 2014 Jul 08;7(333):ra65
pubmed: 25005229
Prog Lipid Res. 2018 Jul;71:43-53
pubmed: 29842906
Plant Signal Behav. 2016 Dec;11(12):e1253647
pubmed: 27901636
Plant Cell Environ. 2015 Mar;38(3):614-24
pubmed: 25074439
Planta. 2014 Mar;239(3):565-75
pubmed: 24271006
Int J Mol Sci. 2019 Jan 02;20(1):
pubmed: 30609769
J Biol Chem. 2006 Nov 10;281(45):34299-311
pubmed: 16980311
Cell. 2016 Oct 6;167(2):313-324
pubmed: 27716505
Plant Cell Environ. 2019 Feb;42(2):536-548
pubmed: 30175516
Prog Lipid Res. 2016 Apr;62:55-74
pubmed: 26783886
Plant Physiol. 2003 Jan;131(1):309-16
pubmed: 12529538
Mol Plant. 2013 Sep;6(5):1692-702
pubmed: 23686948
Plant J. 2002 Feb;29(3):245-55
pubmed: 11844103
Sci Signal. 2011 Nov 29;4(201):re4
pubmed: 22126965
J Exp Bot. 2010 Jul;61(12):3199-210
pubmed: 20522527
J Exp Bot. 2007;58(14):3905-14
pubmed: 18000017
Trends Plant Sci. 2005 Aug;10(8):368-75
pubmed: 16023886
Plant Physiol. 2020 Jan;182(1):361-377
pubmed: 31570508
Plant Physiol Biochem. 2015 Dec;97:175-86
pubmed: 26476791
Biosci Biotechnol Biochem. 2004 Sep;68(9):1966-76
pubmed: 15388974
Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9508-13
pubmed: 15197253
FEBS Lett. 2009 Sep 17;583(18):2982-6
pubmed: 19716822
Plant Cell Physiol. 2009 Dec;50(12):2123-32
pubmed: 19880399
Plant Cell Physiol. 2009 Jan;50(1):78-89
pubmed: 19017627
J Lipid Res. 2009 Apr;50 Suppl:S260-5
pubmed: 19098305
Plant J. 2012 Nov;72(3):436-49
pubmed: 22738204
PLoS Genet. 2016 Mar 04;12(3):e1005835
pubmed: 26943172
Trends Plant Sci. 2013 Sep;18(9):496-504
pubmed: 23664415
Plant Physiol. 2012 May;159(1):450-60
pubmed: 22392280
J Biol Chem. 2012 Mar 9;287(11):8286-96
pubmed: 22275366
Plant Cell Environ. 2019 Mar;42(3):931-946
pubmed: 30338858
Plant J. 2011 Oct;68(1):64-73
pubmed: 21645145
Plant J. 2005 Jul;43(1):107-17
pubmed: 15960620
Methods Mol Biol. 2013;1009:253-9
pubmed: 23681540
Biochem J. 2010 Jul 1;429(1):73-83
pubmed: 20397974
Cell Mol Life Sci. 2012 Oct;69(19):3165-73
pubmed: 22828864
Plant Cell. 2008 Mar;20(3):803-16
pubmed: 18364466
Plant Physiol. 2016 Jul;171(3):1569-80
pubmed: 27208297
Plant Cell Physiol. 2015 Jun;56(6):1043-52
pubmed: 25917608
Plant Cell Physiol. 2009 Jul;50(7):1345-63
pubmed: 19541597
Plant Cell Environ. 2015 Jul;38(7):1391-403
pubmed: 25474382
Biochem J. 2009 Dec 10;424(3):439-48
pubmed: 19785574
Proc Natl Acad Sci U S A. 2009 May 19;106(20):8380-5
pubmed: 19420218
Plant J. 2004 Aug;39(4):527-36
pubmed: 15272872
Front Plant Sci. 2012 Mar 19;3:51
pubmed: 22639650
BMC Plant Biol. 2008 Apr 28;8:49
pubmed: 18442365
Plant Physiol. 2012 Oct;160(2):868-83
pubmed: 22885934
J Biol Chem. 2013 Apr 26;288(17):11834-44
pubmed: 23504314
OMICS. 2011 Dec;15(12):859-72
pubmed: 22136638
J Biol Chem. 2011 Apr 15;286(15):13336-45
pubmed: 21330371
Plant Sci. 2019 Oct;287:110190
pubmed: 31481213
Mol Plant. 2013 Mar;6(2):559-69
pubmed: 23335733
Plant Physiol. 2009 Jul;150(3):1503-14
pubmed: 19439573
Plant Sci. 2019 Feb;279:45-50
pubmed: 30709492
Plant J. 2001 Jun;26(5):479-86
pubmed: 11439134
Nat Struct Mol Biol. 2010 Sep;17(9):1102-8
pubmed: 20729862
Plant Cell Environ. 2010 Apr;33(4):627-35
pubmed: 19968827
Plant Cell. 2012 Nov;24(11):4555-76
pubmed: 23150630
Biochem J. 2013 Mar 15;450(3):573-81
pubmed: 23323832
EMBO J. 2004 Feb 11;23(3):572-81
pubmed: 14749726
Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1717-22
pubmed: 21220313
Methods Mol Biol. 2007;354:1-9
pubmed: 17172739
Biochim Biophys Acta. 2009 Sep;1791(9):927-35
pubmed: 19289179
J Biol Chem. 2008 Apr 4;283(14):8885-92
pubmed: 18218618
Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21425-30
pubmed: 19955405
Plant Cell Physiol. 2010 Nov;51(11):1821-39
pubmed: 20980270
FEBS Lett. 1999 May 28;451(3):220-6
pubmed: 10371193
Plant Physiol. 2020 Feb;182(2):1142-1160
pubmed: 31699848
J Integr Plant Biol. 2018 Sep;60(9):851-863
pubmed: 29660254
Plant J. 2014 Aug;79(4):584-96
pubmed: 24844563
BMC Plant Biol. 2016 Jun 13;16(1):136
pubmed: 27297076
New Phytol. 2019 Mar;221(4):1935-1949
pubmed: 30320882
Plant Cell. 2019 Feb;31(2):399-416
pubmed: 30674693
Anal Biochem. 1993 Apr;210(1):179-87
pubmed: 8489015
Plant Cell. 2009 Aug;21(8):2357-77
pubmed: 19690149
Plant Physiol. 2008 May;147(1):381-90
pubmed: 18359842
Curr Opin Plant Biol. 2011 Dec;14(6):650-7
pubmed: 21839668
Front Plant Sci. 2015 May 28;6:387
pubmed: 26074946
Plant Cell Environ. 2016 May;39(5):1029-48
pubmed: 26510494
Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21419-24
pubmed: 19955427
Plant Cell. 2009 Oct;21(10):3170-84
pubmed: 19855047
Front Plant Sci. 2013 Dec 23;4:525
pubmed: 24391659
New Phytol. 2010 Nov;188(3):762-73
pubmed: 20796215
Nat Plants. 2017 Jan 06;3:16204
pubmed: 28059081
Genes Dev. 2010 Aug 15;24(16):1695-708
pubmed: 20713515
Plant Cell. 2002 Dec;14(12):3089-99
pubmed: 12468729
Plant Cell. 2007 Feb;19(2):485-94
pubmed: 17307925
Plant Cell. 2011 Jun;23(6):2391-404
pubmed: 21665998
Curr Opin Plant Biol. 2010 Oct;13(5):495-502
pubmed: 20934900
Nat Plants. 2019 Sep;5(9):1012-1021
pubmed: 31451794
Science. 2004 Jun 11;304(5677):1644-7
pubmed: 15192221
Physiol Plant. 2013 Jan;147(1):15-27
pubmed: 22519646
Curr Biol. 2002 Apr 30;12(9):695-704
pubmed: 12007412
Plant Cell. 2010 Aug;22(8):2642-59
pubmed: 20699393
Plant J. 2013 May;74(3):372-82
pubmed: 23452338
J Biol Chem. 2015 Nov 6;290(45):26900-13
pubmed: 26370084
J Exp Bot. 2015 Apr;66(7):1721-36
pubmed: 25680793