Screening for depression in movement disorders clinic.
Depression
Diagnosis
Mood disorder
Movement disorder
Neuropsychiatry
Parkinson’s disease
Journal
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
ISSN: 1590-3478
Titre abrégé: Neurol Sci
Pays: Italy
ID NLM: 100959175
Informations de publication
Date de publication:
Mar 2021
Mar 2021
Historique:
received:
04
02
2020
accepted:
02
07
2020
pubmed:
19
7
2020
medline:
15
5
2021
entrez:
19
7
2020
Statut:
ppublish
Résumé
Depression is the most common, though often under-recognised, neuropsychiatric disturbance in movement disorders (MD). This study aimed to establish whether a briefer screening measure such as a visual analogue screening measure (Emotions Thermometer) or Neurological Disorders Depression Inventory for Epilepsy (NDDI-E) could be a potentially suitable screening tool for depression in MD patients. Patients attending a regional MD outpatient clinic completed the Emotional Thermometer 7-item tool (ET7), the Hospital Anxiety and Depression Scale (HADS) and the Neurological Disorders Depression Inventory for Epilepsy (NDDIE). We used the Major Depression Inventory which provided the diagnosis of depression based on ICD-10 and DSM-IV as our diagnostic gold standard to compare the performance of ET7 and its individual sub-scales, its briefer version ET4, HADS, and NDDIE. Sensitivity, specificity, positive predictive value, negative predictive value and receiver operating characteristic curves were calculated to compare the performance of the screening tools. In total, 188 patients were included in the analysis. The most accurate tools as determined by Receiver Operating Characteristics curve were HADS-D for ICD-10 depressive episode and DepT for DSM-IV major depression. ET4 performed well as a 'rule-out' screening tool for both DSM-IV and ICD-10 depression. ET4 performance was comparable to HADS without the need for clinician scoring. The briefer ET4 performed almost as well as ET7. Emotions Thermometer and NDDI-E are quick and reliable screening tools for depression in the MD population and are comparable to HADS. We suggest routine use of visual analogue ET4 as it is briefer, requires less time to complete and does not require scoring from the clinicians. It has the potential to be widely implemented across busy neurology clinics to assist in depression screening.
Sections du résumé
BACKGROUND
BACKGROUND
Depression is the most common, though often under-recognised, neuropsychiatric disturbance in movement disorders (MD).
OBJECTIVE
OBJECTIVE
This study aimed to establish whether a briefer screening measure such as a visual analogue screening measure (Emotions Thermometer) or Neurological Disorders Depression Inventory for Epilepsy (NDDI-E) could be a potentially suitable screening tool for depression in MD patients.
METHOD
METHODS
Patients attending a regional MD outpatient clinic completed the Emotional Thermometer 7-item tool (ET7), the Hospital Anxiety and Depression Scale (HADS) and the Neurological Disorders Depression Inventory for Epilepsy (NDDIE). We used the Major Depression Inventory which provided the diagnosis of depression based on ICD-10 and DSM-IV as our diagnostic gold standard to compare the performance of ET7 and its individual sub-scales, its briefer version ET4, HADS, and NDDIE. Sensitivity, specificity, positive predictive value, negative predictive value and receiver operating characteristic curves were calculated to compare the performance of the screening tools.
RESULTS
RESULTS
In total, 188 patients were included in the analysis. The most accurate tools as determined by Receiver Operating Characteristics curve were HADS-D for ICD-10 depressive episode and DepT for DSM-IV major depression. ET4 performed well as a 'rule-out' screening tool for both DSM-IV and ICD-10 depression. ET4 performance was comparable to HADS without the need for clinician scoring. The briefer ET4 performed almost as well as ET7.
CONCLUSION
CONCLUSIONS
Emotions Thermometer and NDDI-E are quick and reliable screening tools for depression in the MD population and are comparable to HADS. We suggest routine use of visual analogue ET4 as it is briefer, requires less time to complete and does not require scoring from the clinicians. It has the potential to be widely implemented across busy neurology clinics to assist in depression screening.
Identifiants
pubmed: 32681218
doi: 10.1007/s10072-020-04571-7
pii: 10.1007/s10072-020-04571-7
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
969-978Références
Ketharanathan T, Hanwella R, Weerasundera R, Silva VAD (2014) Major depressive disorder in Parkinson’s disease: a cross-sectional study from Sri Lanka. BMC Psychiatry 14(1):278
doi: 10.1186/s12888-014-0278-8
McDonald WM, Richard I, DeLong MR (2003) Prevalence, etiology, and treatment of depression in Parkinson’s disease. Biol Psychiatry 54(3):363–375
doi: 10.1016/S0006-3223(03)00530-4
Pankratz N, Marder KS, Halter CA, Rudolph A, Shults CW, Nichols WC et al (2008) Clinical correlates of depressive symptoms in familial Parkinson’s disease. Mov Disord. 23(15):2216–2223
doi: 10.1002/mds.22285
Shulman LM, Taback RL, Bean J, Weiner WJ (2001) Comorbidity of the nonmotor symptoms of Parkinson’s disease. Mov Disord. 16:507–510
doi: 10.1002/mds.1099
Cummings JL (1992) Depression and Parkinson’s disease: a review. Am J Psychiatry 149:443–454
doi: 10.1176/ajp.149.4.443
Aarsland D, Pahlhagen S, Ballard CG, Ehrt UE, Svenningsson P (2012) Depression in Parkinson disease–epidemiology, mechanisms and management. Nat Rev Neurol 11:35–47
doi: 10.1038/nrneurol.2011.189
Reijnders JSAM, Ehrt U, Weber WEJ, Aarsland D, Leentjens AFG (2008 Jennifer S.A.M. Reijnders, MA,1 Uwe Ehrt, MD,2 Wim E.J. Weber, MD, PhD,3 Jan) A systematic review of prevalence studies of depression in Parkinson’s disease. Mov Disord 23(2):183–189
doi: 10.1002/mds.21803
Kuopio AM, Marttila RJ, Helenius H, Toivonen M, Rinne UK (2000) The quality of life in Parkinson’s disease. Mov Disord. 15(2):216–223
doi: 10.1002/1531-8257(200003)15:2<216::AID-MDS1003>3.0.CO;2-#
Lemke MR (2008) Depressive symptoms in Parkinson’s disease. Eur J Neurol 15(Supple 1):21–25
doi: 10.1111/j.1468-1331.2008.02058.x
Burn DJ (2002) Depression in Parkinson’s disease. Eur J Neurol 9(Suppl 1):44–54
doi: 10.1046/j.1468-1331.9.s3.6.x
Marsh L (2013) Depression and Parkinson’s disease: current knowledge. Curr Neurol Neurosci Rep 13(12):409
doi: 10.1007/s11910-013-0409-5
Slaughter JR, Slaughter KA, Dave N, Holmes SE, Martens MP (2001) Prevalence, clinical manifestations, aetiology, and treatment of depression in Parkinson's disease. J Neuropsychiatr Clin Neurosci 13:187–196
doi: 10.1176/jnp.13.2.187
Ceylan D, Erer S, Zarifoğlu M, Türkeş N, Özkaya G (2019) Evaluation of anxiety and depression scales and quality of LIFE in cervical dystonia patients on Botulinum toxin therapy and their relatives. Neurol Sci 40(4):725–731
doi: 10.1007/s10072-019-3719-9
Conte A, Berardelli I, Ferrazzano G, Pasquini M, Berardelli A, Fabbrini G (2016) Non-motor symptoms in patients with adult-onset focal dystonia: sensory and psychiatric disturbances. Parkinsonism Relat Disord 22:S111–S114
doi: 10.1016/j.parkreldis.2015.09.001
Chunling W, Zheng X (2016l) Review on clinical update of essential tremor. Neurol Sci 37(4):495–502
doi: 10.1007/s10072-015-2380-1
Aslam S, Zhang N, Adler CH, Caviness JN, Driver-Dunckley E, Mehta SH, Sabbagh MN, Belden C, Zamrini E, Beach TG, Shill HA (2017) Essential tremor and depression. Mov Disord Clin Pract 4(6):838–842
doi: 10.1002/mdc3.12530
Berman BD, Junker J, Shelton E, Sillau S, Jinnah H, Perlmutter JS et al (2017) Psychiatric Associations of Adult-Onset Focal Dystonia Phenotypes. J Neurol Neurosurg Psychiatry 88(7):595–602
doi: 10.1136/jnnp-2016-315461
Tomic S, Petkovic I, Pucic T, Resan B, Juric S, Rotim T (2016) Cervical dystonia and quality of life. Acta Neurol Belg 116(4):589–592
doi: 10.1007/s13760-016-0634-1
Shulman L, Taback R, Rabinstein A et al (2002) Non-recognition of depression and other non-motor symptoms in Parkinson’s disease. Parkinsonism Relat Disord 8:193–197
doi: 10.1016/S1353-8020(01)00015-3
Williams JR, Hirsch ES, Anderson K, Bush AL, Goldstein SR, Grill S, Lehmann S, Little JT, Margolis RL, Palanci J, Pontone G, Weiss H, Rabins P, Marsh L (2012) A comparison of nine scales to detect depression in Parkinson disease: which scale to use? Neurology. 78(13):998–1006
doi: 10.1212/WNL.0b013e31824d587f
Goodarzi Z, Ismail Z (2017) A practical approach to detection and treatment of depression in Parkinson disease and dementia. Neurol Clin Pract 7(2):128–140
doi: 10.1212/CPJ.0000000000000351
Mondolo F, Jahanshahi M, Gran A, Biasutti E, Cacciatori E, Di Benedetto P (2006) The validity of the Hospital Anxiety and Depression Scale and the Geriatric Depression Scale in Parkinson’s disease. Behav Neurol 17(2):109–115
doi: 10.1155/2006/136945
Mitchell AJ, Baker-Glenn EA, Granger L, Symonds P (2009 a Alex J. Mitchell Elena A. Baker-Glenn Lorraine Granger Paul Symonds) Can the distress thermometer be improved by additional mood domains? Part I. Initial validation of the emotional thermometer tool. Psychooncology 19:125–133
doi: 10.1002/pon.1523
Mitchell AJ, Baker-Glenn EA, Park B, Granger L, Symonds P (2009b) Can the distress thermometer be improved by additional mood domains? Part II. What is the optimal combination of emotional thermometers? Psychooncology. 19:134–140
doi: 10.1002/pon.1557
Rampling J, Mitchell AJ, Von-Oertzen T, Docker J, Jackson J, Hannah C et al (2012) Screening for depression in epilepsy clinics. A comparison of conventional and visual-analog methods. Epilepsia. 53(10):1713–1721
doi: 10.1111/j.1528-1167.2012.03571.x
Thompson AGB, Sheldon R, Poole N, Varela R, White S, Jones P et al (2019) A new way of rapidly screening for depression in multiple sclerosis using emotional thermometers. Acta Neuropsychiatr. 31(3):151–158
Cuijpers P, Dekker J, Noteboom A, Smits N, Peen J (2007) Sensitivity and specificity of the major depression inventory in outpatients. BMC Psychiatry 7:39
doi: 10.1186/1471-244X-7-39
Jacobsen PB, Donovan KA, Trask PC, Fleishman SB, Zabora J, Baker F, Holland JC (2005) Screening for Psychologic distress in ambulatory cancer patient. A multicenter evaluation of the distress thermometer. Cancer. 103:1494–1502
doi: 10.1002/cncr.20940
Youden W (1950) Index for rating diagnostic tests. Cancer 3(1):32–35
doi: 10.1002/1097-0142(1950)3:1<32::AID-CNCR2820030106>3.0.CO;2-3
Mitchell AJ (2011) Sensitivity × PPV is a recognized test called the Clinical Utility Index (CUI+). Eur J Epidemiol, Springer Verlag 26(3):251–252
doi: 10.1007/s10654-011-9561-x
Mitchell AJ, Pezzullo J http://www.clinicalutility.co.uk/ . [Online].; 2012 [cited 2018 11 01
Jones SR, Carley S, Harrison M (2003) An introduction to power and sample size estimation. Emerg Med J 20:453–458
doi: 10.1136/emj.20.5.453
Bech P, Rasmussen NA, Olsen LR, Noerholm V, Abildgaard W (2001) The sensitivity and specificity of the major depression inventory using the present state examination as the index of diagnostic validity. J Affect Disord 66:159–164
doi: 10.1016/S0165-0327(00)00309-8
Bech P, Timmerby N, Martiny K, Lunde M, Soendergaard S (2015) Psychometric evaluation of the Major Depression Inventory (MDI) as depression severity scale using the LEAD (Longitudinal Expert Assessment of All Data) as index of validity. BMC Psychiatry 15(190)
Zigmond AS, Snaith RP (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67(6):361–370
doi: 10.1111/j.1600-0447.1983.tb09716.x
Verhey F (2001) The psychometric properties of the hospital anxiety and depression scale in patients with Parkinson’s disease. Acta Neuropsychiatr 13(4):83–85
Mitchell AJ. http://www.psycho-oncology.info/ET.htm . [Online]. [cited 2018 Nov 9
Gilliam FG, Barry JJ, Hermann BP, Meador KJ, Vahle V, Kanner AM (2006) Rapid detection of major depression in epilepsy: a multicentre study. Lancet Neurol 5(5):399–405
doi: 10.1016/S1474-4422(06)70415-X
Gilbody S, Sheldon T, Wessely S (2006) Should we screen for depression? BMJ. 332:1027–1030
doi: 10.1136/bmj.332.7548.1027
McCullough PK (1991) Geriatric depression: atypical presentations, hidden meanings. Geriatrics. 46(10):72–76
pubmed: 1916304
Trojano L, Papagno C (2018) Cognitive and behavioral disorders in Parkinson's disease: an update. II: Behavioral Disorders. Neurol Sci 39(1):53–61
doi: 10.1007/s10072-017-3155-7
Mitchell AJ, Ioannou N, Rampling JM, Sajid A, von Oertzen TJ, Cock HR, Agrawal N (2013) Which symptoms are indicative of depression in epilepsy settings? An analysis of the diagnostic significance of somatic and non-somatic symptoms. J Affect Disord 150(3):861–867
doi: 10.1016/j.jad.2013.03.020
Ismail Z, Malick A, Smith EE, Schweizer T, Fischer C (2014) Depression versus dementia: is this construct still relevant? Neurodegener Dis Manag 4(2):119–126
doi: 10.2217/nmt.14.5
den Brok M, van Dalen J, van Gool W, Moll van Charante E, de Bie R, Richard E (2015) Apathy in Parkinson’s disease: a systematic review and meta-analysis. Mov Disord 30(6):759–769
doi: 10.1002/mds.26208