Pulmonary deposition of budesonide/glycopyrronium/formoterol fumarate dihydrate metered dose inhaler formulated using co-suspension delivery technology in healthy male subjects.
Budesonide
Formoterol fumarate
Gamma scintigraphy
Glycopyrronium
Pulmonary deposition
Journal
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
ISSN: 1879-0720
Titre abrégé: Eur J Pharm Sci
Pays: Netherlands
ID NLM: 9317982
Informations de publication
Date de publication:
01 Oct 2020
01 Oct 2020
Historique:
received:
10
12
2019
revised:
14
07
2020
accepted:
15
07
2020
pubmed:
19
7
2020
medline:
22
6
2021
entrez:
19
7
2020
Statut:
ppublish
Résumé
This gamma scintigraphy imaging study assessed pulmonary, extrathoracic and regional lung deposition patterns of a radiolabelled inhaled corticosteroid/long-acting muscarinic antagonist/long-acting β
Identifiants
pubmed: 32682074
pii: S0928-0987(20)30261-X
doi: 10.1016/j.ejps.2020.105472
pii:
doi:
Substances chimiques
Bronchodilator Agents
0
Drug Combinations
0
Budesonide
51333-22-3
Glycopyrrolate
V92SO9WP2I
Formoterol Fumarate
W34SHF8J2K
Types de publication
Clinical Trial, Phase I
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
105472Informations de copyright
Copyright © 2020 AstraZeneca. Published by Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest Samuel Israel has no conflicts to report. Ashish Kumar is an employee of Kelly Services Global LLC. Nicolas Roche reports grants and personal fees from Boehringer Ingelheim, Novartis, Pfizer and personal fees from AstraZeneca, Chiesi, Cipla, GlaxoSmithKline, Mundipharma, Sanofi, Sandoz, Teva, Trudell, Zambon and 3 M. Omar S. Usmani reports academic grants from AstraZeneca, Boehringer Ingelheim, Chiesi, GlaxoSmithKline and personal fees from Aerocrine, AstraZeneca, Boehringer Ingelheim, Chiesi, Cipla, Mundipharma, NAPP, Prosonix, Sandoz, Takeda and Zentiva. Magnus Aurivillius and Paul Dorinsky are employees of AstraZeneca. Kiernan DeAngelis is a former employee of AstraZeneca.