Renewable and tuneable bio-LPG blends derived from amino acids.

Bio-LPG Biofuels Butane Escherichia coli Isobutane Microbial pathway engineering Propane

Journal

Biotechnology for biofuels
ISSN: 1754-6834
Titre abrégé: Biotechnol Biofuels
Pays: England
ID NLM: 101316935

Informations de publication

Date de publication:
2020
Historique:
received: 21 05 2020
accepted: 08 07 2020
entrez: 21 7 2020
pubmed: 21 7 2020
medline: 21 7 2020
Statut: epublish

Résumé

Microbial biorefinery approaches are beginning to define renewable and sustainable routes to clean-burning and non-fossil fuel-derived gaseous alkanes (known as 'bio-LPG'). The most promising strategies have used a terminal fatty acid photodecarboxylase, enabling light-driven propane production from externally fed waste butyric acid. Use of Multiple pathways from the amino acids valine, leucine and isoleucine were designed in This study highlights new microbial pathways for the production of clean-burning bio-LPG fuels from amino acids. The use of stable

Sections du résumé

BACKGROUND BACKGROUND
Microbial biorefinery approaches are beginning to define renewable and sustainable routes to clean-burning and non-fossil fuel-derived gaseous alkanes (known as 'bio-LPG'). The most promising strategies have used a terminal fatty acid photodecarboxylase, enabling light-driven propane production from externally fed waste butyric acid. Use of
RESULTS RESULTS
Multiple pathways from the amino acids valine, leucine and isoleucine were designed in
CONCLUSIONS CONCLUSIONS
This study highlights new microbial pathways for the production of clean-burning bio-LPG fuels from amino acids. The use of stable

Identifiants

pubmed: 32684978
doi: 10.1186/s13068-020-01766-0
pii: 1766
pmc: PMC7362463
doi:

Types de publication

Journal Article

Langues

eng

Pagination

125

Subventions

Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/M017702/1
Pays : United Kingdom

Informations de copyright

© The Author(s) 2020.

Déclaration de conflit d'intérêts

Competing interestsA patent application (PCT/EP2019/060013) entitled ‘Hydrocarbon production’ is pending in relation to the production of hydrocarbon gases in engineered microbial strains. M.S. and N.S.S. are founding directors of C3 Biotech Ltd.

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Auteurs

Mohamed Amer (M)

EPSRC/BBSRC Future Biomanufacturing Research Hub, BBSRC/EPSRC, Synthetic Biology Research Centre SYNBIOCHEM Manchester Institute of Biotechnology and School of Chemistry, The University of Manchester, Manchester, M1 7DN UK.

Robin Hoeven (R)

EPSRC/BBSRC Future Biomanufacturing Research Hub, BBSRC/EPSRC, Synthetic Biology Research Centre SYNBIOCHEM Manchester Institute of Biotechnology and School of Chemistry, The University of Manchester, Manchester, M1 7DN UK.

Paul Kelly (P)

EPSRC/BBSRC Future Biomanufacturing Research Hub, BBSRC/EPSRC, Synthetic Biology Research Centre SYNBIOCHEM Manchester Institute of Biotechnology and School of Chemistry, The University of Manchester, Manchester, M1 7DN UK.

Matthew Faulkner (M)

EPSRC/BBSRC Future Biomanufacturing Research Hub, BBSRC/EPSRC, Synthetic Biology Research Centre SYNBIOCHEM Manchester Institute of Biotechnology and School of Chemistry, The University of Manchester, Manchester, M1 7DN UK.

Michael H Smith (MH)

C3 Biotechnologies Ltd, The Railway Goods Yard, Middleton-in-Lonsdale, Lancashire, LA6 2NF UK.

Helen S Toogood (HS)

EPSRC/BBSRC Future Biomanufacturing Research Hub, BBSRC/EPSRC, Synthetic Biology Research Centre SYNBIOCHEM Manchester Institute of Biotechnology and School of Chemistry, The University of Manchester, Manchester, M1 7DN UK.

Nigel S Scrutton (NS)

EPSRC/BBSRC Future Biomanufacturing Research Hub, BBSRC/EPSRC, Synthetic Biology Research Centre SYNBIOCHEM Manchester Institute of Biotechnology and School of Chemistry, The University of Manchester, Manchester, M1 7DN UK.
C3 Biotechnologies Ltd, The Railway Goods Yard, Middleton-in-Lonsdale, Lancashire, LA6 2NF UK.

Classifications MeSH