What is the most useful imaging parameter to explore the prognostic value of the right ventricular function at the time of multimodality cardiovascular imaging?


Journal

Echocardiography (Mount Kisco, N.Y.)
ISSN: 1540-8175
Titre abrégé: Echocardiography
Pays: United States
ID NLM: 8511187

Informations de publication

Date de publication:
08 2020
Historique:
received: 10 08 2019
revised: 28 12 2019
accepted: 21 04 2020
pubmed: 21 7 2020
medline: 24 6 2021
entrez: 21 7 2020
Statut: ppublish

Résumé

Right ventricular (RV) function is a powerful independent predictor of adverse heart failure outcomes. The aim of this study was to compare the predictive value of main RV systolic imaging parameters for outcome. Seventy-nine patients underwent comprehensive cardiovascular imaging modalities including transthoracic echocardiography, cardiac magnetic resonance (CMR) imaging, and tomographic equilibrium radionuclide ventriculography (ERV) for the assessment of RV function. The composite primary endpoint (CPE) was defined by the occurrence of death, heart transplantation, implantation of a left ventricular assist device, or new-onset acute heart failure. During a mean follow-up of 13 ± 9 months, 15 (19%) patients reached the CPE. The areas under the receiver operator characteristic curves for the prediction of the CPE were 0.922 (P < .001), 0.913 (P < .001), 0.906 (P < .001), 0.849 (P = .002), 0.837 (P = .003), 0.799 (P = .009), 0.792 (P = .011), 0.753 (P = .026), 0.720 (P = .053), and 0.608 (P = .346) for integral systolic S' wave tricuspid annular velocity, RV free wall longitudinal strain (RVFWLS), RV fractional area change, tricuspid annular plane systolic excursion, RV ejection fraction (RVEF) by CMR using the 4-chamber slices, peak systolic S' wave tricuspid annular velocity, RVEF by CMR using short-axis slices, RVEF by ERV, RV myocardial performance index, and RV myocardial acceleration during isovolumic contraction, respectively. Echocardiographic parameters, and particularly integral systolic S' wave tricuspid annular velocity and RVFWLS, have the best prognostic performance.

Sections du résumé

BACKGROUND
Right ventricular (RV) function is a powerful independent predictor of adverse heart failure outcomes. The aim of this study was to compare the predictive value of main RV systolic imaging parameters for outcome.
METHODS
Seventy-nine patients underwent comprehensive cardiovascular imaging modalities including transthoracic echocardiography, cardiac magnetic resonance (CMR) imaging, and tomographic equilibrium radionuclide ventriculography (ERV) for the assessment of RV function. The composite primary endpoint (CPE) was defined by the occurrence of death, heart transplantation, implantation of a left ventricular assist device, or new-onset acute heart failure.
RESULTS
During a mean follow-up of 13 ± 9 months, 15 (19%) patients reached the CPE. The areas under the receiver operator characteristic curves for the prediction of the CPE were 0.922 (P < .001), 0.913 (P < .001), 0.906 (P < .001), 0.849 (P = .002), 0.837 (P = .003), 0.799 (P = .009), 0.792 (P = .011), 0.753 (P = .026), 0.720 (P = .053), and 0.608 (P = .346) for integral systolic S' wave tricuspid annular velocity, RV free wall longitudinal strain (RVFWLS), RV fractional area change, tricuspid annular plane systolic excursion, RV ejection fraction (RVEF) by CMR using the 4-chamber slices, peak systolic S' wave tricuspid annular velocity, RVEF by CMR using short-axis slices, RVEF by ERV, RV myocardial performance index, and RV myocardial acceleration during isovolumic contraction, respectively.
CONCLUSION
Echocardiographic parameters, and particularly integral systolic S' wave tricuspid annular velocity and RVFWLS, have the best prognostic performance.

Identifiants

pubmed: 32686860
doi: 10.1111/echo.14686
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1233-1242

Informations de copyright

© 2020 Wiley Periodicals LLC.

Références

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Auteurs

Stéphanie Cazalbou (S)

Department of Cardiology, University Hospital of Rangueil, Toulouse, France.
Cardiac Imaging Center, Toulouse University Hospital, France.

Vanessa Chong Fah Shen (V)

Department of Cardiology, University Hospital of Rangueil, Toulouse, France.
Cardiac Imaging Center, Toulouse University Hospital, France.

Antoine Petermann (A)

Cardiac Imaging Center, Toulouse University Hospital, France.
Department of Radiology, University Hospital of Rangueil, Toulouse, France.

Damien Eyharts (D)

Department of Cardiology, University Hospital of Rangueil, Toulouse, France.
Cardiac Imaging Center, Toulouse University Hospital, France.

Pauline Fournier (P)

Department of Cardiology, University Hospital of Rangueil, Toulouse, France.
Cardiac Imaging Center, Toulouse University Hospital, France.

Eve Cariou (E)

Department of Cardiology, University Hospital of Rangueil, Toulouse, France.
Cardiac Imaging Center, Toulouse University Hospital, France.
Medical School of Rangueil, University Paul Sabatier, Toulouse, France.

Yoan Lavie-Badie (Y)

Department of Cardiology, University Hospital of Rangueil, Toulouse, France.
Cardiac Imaging Center, Toulouse University Hospital, France.

Alexia Hennig (A)

Cardiac Imaging Center, Toulouse University Hospital, France.
Department of Radiology, University Hospital of Rangueil, Toulouse, France.
Medical School of Rangueil, University Paul Sabatier, Toulouse, France.

Jérôme Roncalli (J)

Department of Cardiology, University Hospital of Rangueil, Toulouse, France.
Medical School of Purpan, University Paul Sabatier, Toulouse, France.

Hervé Rousseau (H)

Cardiac Imaging Center, Toulouse University Hospital, France.
Department of Radiology, University Hospital of Rangueil, Toulouse, France.
Medical School of Rangueil, University Paul Sabatier, Toulouse, France.

Didier Carrié (D)

Department of Cardiology, University Hospital of Rangueil, Toulouse, France.
Cardiac Imaging Center, Toulouse University Hospital, France.
Medical School of Purpan, University Paul Sabatier, Toulouse, France.

Michel Galinier (M)

Department of Cardiology, University Hospital of Rangueil, Toulouse, France.
Cardiac Imaging Center, Toulouse University Hospital, France.
Medical School of Rangueil, University Paul Sabatier, Toulouse, France.

Isabelle Berry (I)

Cardiac Imaging Center, Toulouse University Hospital, France.
Medical School of Rangueil, University Paul Sabatier, Toulouse, France.
Department of Nuclear Medicine, University Hospital of Rangueil, Toulouse, France.

Olivier Lairez (O)

Department of Cardiology, University Hospital of Rangueil, Toulouse, France.
Cardiac Imaging Center, Toulouse University Hospital, France.
Medical School of Rangueil, University Paul Sabatier, Toulouse, France.
Department of Nuclear Medicine, University Hospital of Rangueil, Toulouse, France.

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