Pre-operative Diagnosis of Silent Coronary Ischaemia May Reduce Post-operative Death and Myocardial Infarction and Improve Survival of Patients Undergoing Lower Extremity Surgical Revascularisation.
Aged
Asymptomatic Diseases
Case-Control Studies
Computed Tomography Angiography
Coronary Angiography
Coronary Artery Disease
/ complications
Coronary Stenosis
/ complications
Female
Fractional Flow Reserve, Myocardial
Humans
Lower Extremity
/ blood supply
Male
Middle Aged
Myocardial Infarction
/ diagnostic imaging
Peripheral Arterial Disease
/ diagnostic imaging
Predictive Value of Tests
Prospective Studies
Risk Assessment
Risk Factors
Time Factors
Vascular Surgical Procedures
/ adverse effects
Coronary CT derived fractional flow reserve
Long term survival
Peripheral artery disease
Post-operative mortality
Silent coronary ischaemia
Surgical revascularisation
Journal
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
ISSN: 1532-2165
Titre abrégé: Eur J Vasc Endovasc Surg
Pays: England
ID NLM: 9512728
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
received:
15
11
2019
revised:
23
04
2020
accepted:
17
05
2020
pubmed:
28
7
2020
medline:
21
10
2020
entrez:
26
7
2020
Statut:
ppublish
Résumé
Patients undergoing peripheral vascular surgery have increased risk of death and myocardial infarction (MI), which may be due to unsuspected (silent) coronary ischaemia. The aim was to determine whether pre-operative diagnosis of silent ischaemia using coronary computed tomography (CT) derived fractional flow reserve (FFR This was a single centre prospective study with historic controls. Patients with no cardiac symptoms undergoing lower extremity surgical revascularisation with pre-operative coronary CTA-FFR There were no statistically significant differences between CT angiography (CTA-FFR Pre-operative diagnosis of silent coronary ischaemia in patients undergoing lower extremity revascularisation surgery can facilitate multidisciplinary patient care with selective post-operative coronary revascularisation. This strategy reduced post-operative death and MI and improved one year survival compared with standard care.
Identifiants
pubmed: 32709470
pii: S1078-5884(20)30449-4
doi: 10.1016/j.ejvs.2020.05.027
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
411-420Informations de copyright
Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Conflict of interest C.K.Z. has a financial interest in HeartFlow, Inc.