Clinical Characteristics and Outcomes of Heart Failure Patients With Long-Term Care Insurance - Insights From the Kitakawachi Clinical Background and Outcome of Heart Failure Registry.


Journal

Circulation journal : official journal of the Japanese Circulation Society
ISSN: 1347-4820
Titre abrégé: Circ J
Pays: Japan
ID NLM: 101137683

Informations de publication

Date de publication:
25 08 2020
Historique:
pubmed: 28 7 2020
medline: 14 10 2021
entrez: 28 7 2020
Statut: ppublish

Résumé

In Japan, the long-term care insurance (LTCI) system has an important role in helping elderly people, but there have been no clinical studies that have examined the relationship between the LTCI and prognosis for patients with acute heart failure (HF).Methods and Results:This registry was a prospective multicenter cohort, 1,253 patients were enrolled and 965 patients with acute HF aged ≥65 years were comprised the study group. The composite endpoint included all-cause death and hospitalization for HF after discharge. We divided the patients into 4 groups: (i) patients without LTCI, (ii) patients requiring support level 1 or 2, (iii) patients with care level 1 or 2, and (iv) patients with care levels 3-5. The Kaplan-Meier analysis identified a lower rate of the composite endpoint in group (i) than in the other groups. After adjusting for potentially confounding effects using a Cox proportional regression model, the hazard ratio (HR) of the composite endpoint increased significantly in groups (iii) and (iv) (adjusted HR, 1.62; 95% confidence interval [CI], 1.22-1.98 and adjusted HR, 1.62; 95% CI, 1.23-2.14, respectively) when compared with group (i). However, there was no significant difference between groups (i) and (ii). The level of LTCI was associated with a higher risk of the composite endpoint after discharge in acute HF patients.

Sections du résumé

BACKGROUND
In Japan, the long-term care insurance (LTCI) system has an important role in helping elderly people, but there have been no clinical studies that have examined the relationship between the LTCI and prognosis for patients with acute heart failure (HF).Methods and Results:This registry was a prospective multicenter cohort, 1,253 patients were enrolled and 965 patients with acute HF aged ≥65 years were comprised the study group. The composite endpoint included all-cause death and hospitalization for HF after discharge. We divided the patients into 4 groups: (i) patients without LTCI, (ii) patients requiring support level 1 or 2, (iii) patients with care level 1 or 2, and (iv) patients with care levels 3-5. The Kaplan-Meier analysis identified a lower rate of the composite endpoint in group (i) than in the other groups. After adjusting for potentially confounding effects using a Cox proportional regression model, the hazard ratio (HR) of the composite endpoint increased significantly in groups (iii) and (iv) (adjusted HR, 1.62; 95% confidence interval [CI], 1.22-1.98 and adjusted HR, 1.62; 95% CI, 1.23-2.14, respectively) when compared with group (i). However, there was no significant difference between groups (i) and (ii).
CONCLUSIONS
The level of LTCI was associated with a higher risk of the composite endpoint after discharge in acute HF patients.

Identifiants

pubmed: 32713877
doi: 10.1253/circj.CJ-20-0017
doi:

Types de publication

Clinical Trial Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

1528-1535

Auteurs

Kensuke Takabayashi (K)

Department of Cardiology, Hirakata Kohsai Hospital.

Kotaro Iwatsu (K)

Department of Rehabilitation, Hirakata Kohsai Hospital.

Tsutomu Ikeda (T)

Department of Rehabilitation, Hirakata Kohsai Hospital.

Yuko Morikami (Y)

Department of Cardiology, Hirakata Kohsai Hospital.

Tahei Ichinohe (T)

Department of Cardiology, Hirakata Kohsai Hospital.

Takashi Yamamoto (T)

Department of Cardiology, Hirakata Kohsai Hospital.

Kotoe Takenaka (K)

Department of Cardiology, Hirakata Kohsai Hospital.

Hiroyuki Takenaka (H)

Department of Cardiology, Hirakata Kohsai Hospital.

Hiroyuki Muranaka (H)

Department of Cardiology, Hirakata Kohsai Hospital.

Ryoko Fujita (R)

Department of Cardiology, Hirakata Kohsai Hospital.

Miyuki Okuda (M)

Department of Cardiology, Hirakata Kohsai Hospital.

Osamu Nakajima (O)

Department of Cardiology, Hirakata City Hospital.

Hitoshi Koito (H)

Department of Cardiology, Otokoyama Hospital.

Yuka Terasaki (Y)

Department of Internal Medicine, Arisawa General Hospital.

Tetsuhisa Kitamura (T)

Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University.

Shouji Kitaguchi (S)

Department of Cardiology, Hirakata Kohsai Hospital.

Ryuji Nohara (R)

Department of Cardiology, Hirakata Kohsai Hospital.

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