Electrocardiographic QRS voltage amplitude improvement by intramyocardial radiofrequency ablation in patients with hypertrophic obstructive cardiomyopathy and one year follow up.

Cardiomyopathy, Hypertrophic / diagnosis Echocardiography Electrocardiography Follow-Up Studies Humans Radiofrequency Ablation
ECG QRS wave amplitude Hypertrophic obstructive cardiomyopathy Interventricular septal thickness Liwen procedure Percutaneous intramyocardial septal radiofrequency ablation

Journal

Journal of electrocardiology
ISSN: 1532-8430
Titre abrégé: J Electrocardiol
Pays: United States
ID NLM: 0153605

Informations de publication

Date de publication:
Historique:
received: 19 03 2020
revised: 28 05 2020
accepted: 08 06 2020
pubmed: 30 7 2020
medline: 22 6 2021
entrez: 30 7 2020
Statut: ppublish

Résumé

This study aimed to determine whether the serial changes of the electrocardiogram is associated with regression of left ventricular hypertrophy (LVH) after Liwen procedure. Clinical application of the echocardiography-guided percutaneous intramyocardial septal radiofrequency ablation (PIMSRA, Liwen procedure) is an innovative approach to treat hypertrophic obstructive cardiomyopathy (HOCM). We enrolled 30 consecutive patients with HOCM who had undergone Liwen procedure in our Hypertrophic Cardiomyopathy Center, from June 2016 to January 2018. Electrocardiography (ECG) and echocardiogram were performed before and after Liwen procedure, and at each follow-up (1-week, 1, 3, 6 months and 1 year). The Sokolow-Lyon index (SLi), Q wave, R wave, S wave amplitude of 12-lead ECG and interventricular septal (IVS) thickness, left ventricular mass index (LVMI) by echocardiograms were measured in each patient. The sum of the ECG QRS amplitude on each lead was calculated. The reduction of SLi and QRS amplitude were used as improvement index. The ECG leads with most improvement rate of the QRS wave amplitude of all cases were V1 and V2, both at 90%. The QRS wave amplitude in V1 leads and SLi were positively correlated with IVS thickness and LVMI at baseline and 1 year after Liwen procedure, respectively. The reduction of IVS thickness, LVMI and QRS wave amplitude in leads V1 and V2 were significant at one month after ablation and the follow-up period. SLi was significantly decreased at 3 months during the observation period. Similarly, the improvement of ECG QRS wave amplitude after the Liwen procedure tracked the gradual thinning of the IVS and the changes of SLi reflected the regression of LVH. The QRS wave amplitude reductions in lead V1 and SLi may be good indicators for evaluating the postoperative interventricular septal remodeling of the Liwen procedure.

Sections du résumé

OBJECTIVES
This study aimed to determine whether the serial changes of the electrocardiogram is associated with regression of left ventricular hypertrophy (LVH) after Liwen procedure.
BACKGROUND
Clinical application of the echocardiography-guided percutaneous intramyocardial septal radiofrequency ablation (PIMSRA, Liwen procedure) is an innovative approach to treat hypertrophic obstructive cardiomyopathy (HOCM).
METHODS
We enrolled 30 consecutive patients with HOCM who had undergone Liwen procedure in our Hypertrophic Cardiomyopathy Center, from June 2016 to January 2018. Electrocardiography (ECG) and echocardiogram were performed before and after Liwen procedure, and at each follow-up (1-week, 1, 3, 6 months and 1 year). The Sokolow-Lyon index (SLi), Q wave, R wave, S wave amplitude of 12-lead ECG and interventricular septal (IVS) thickness, left ventricular mass index (LVMI) by echocardiograms were measured in each patient. The sum of the ECG QRS amplitude on each lead was calculated. The reduction of SLi and QRS amplitude were used as improvement index.
RESULTS
The ECG leads with most improvement rate of the QRS wave amplitude of all cases were V1 and V2, both at 90%. The QRS wave amplitude in V1 leads and SLi were positively correlated with IVS thickness and LVMI at baseline and 1 year after Liwen procedure, respectively. The reduction of IVS thickness, LVMI and QRS wave amplitude in leads V1 and V2 were significant at one month after ablation and the follow-up period. SLi was significantly decreased at 3 months during the observation period. Similarly, the improvement of ECG QRS wave amplitude after the Liwen procedure tracked the gradual thinning of the IVS and the changes of SLi reflected the regression of LVH.
CONCLUSION
The QRS wave amplitude reductions in lead V1 and SLi may be good indicators for evaluating the postoperative interventricular septal remodeling of the Liwen procedure.

Identifiants

DOI: 10.1016/j.jelectrocard.2020.06.013 PMID: 32721657
pubmed: 32721657
pii: S0022-0736(20)30183-7
doi: 10.1016/j.jelectrocard.2020.06.013
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

164-169

Informations de copyright

Copyright © 2020. Published by Elsevier Inc.

Auteurs

Lei Zuo (L)

Hypertrophic Cardiomyopathy Center, Department of Ultrasound, XiJing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.

David H Hsi (DH)

Heart&Vascular Institute, Stamford Hospital, Stamford, CT, USA.

Li Zhang (L)

Lankenau Institute for Medical Research, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, USA.

Qin Zhang (Q)

Hypertrophic Cardiomyopathy Center, Department of Ultrasound, XiJing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.

Hong Shao (H)

Department of Cardiology, XiJing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.

Bing Liu (B)

Department of Cardiology, XiJing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.

Changhui Lei (C)

Hypertrophic Cardiomyopathy Center, Department of Ultrasound, XiJing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.

Chuang Ye (C)

Department of Cardiology, XiJing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.

Xin Meng (X)

Hypertrophic Cardiomyopathy Center, Department of Ultrasound, XiJing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.

Guoqing Zhang (G)

Department of Ultrasound, The Affiliated Hospital of XiJing Hospital, Xi'an, Shaanxi, China.

Mengyao Zhou (M)

Hypertrophic Cardiomyopathy Center, Department of Ultrasound, XiJing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.

Jing Li (J)

Hypertrophic Cardiomyopathy Center, Department of Ultrasound, XiJing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.

Yang He (Y)

Xi'an Medical University, Xi'an, Shaanxi, China.

Jianying Guo (J)

Specialty Care Clinic, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China. Electronic address: jyguo@fmmu.edu.cn.

Liwen Liu (L)

Hypertrophic Cardiomyopathy Center, Department of Ultrasound, XiJing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China. Electronic address: liuliwen@fmmu.edu.cn.

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Classifications MeSH

questionsmedicales.fr › Maladies cardiovasculaires › Cardiopathies › Valvulopathies › Maladie de la valve aortique › Cardiomyopathie hypertrophique › Electrocardiographic QRS voltage amplitude...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic cardiovasculaire › Tests de la fonction cardiaque › Échocardiographie › Electrocardiographic QRS voltage amplitude...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Électrodiagnostic › Électrocardiographie › Electrocardiographic QRS voltage amplitude...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études de suivi › Electrocardiographic QRS voltage amplitude...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Electrocardiographic QRS voltage amplitude...
questionsmedicales.fr › Procédures de chirurgie opératoire › Techniques d'ablation › Ablation par radiofréquence › Electrocardiographic QRS voltage amplitude...