Comprehensive Genomic Analysis Reveals the Prognostic Role of

DNA Copy Number Variations Genetic Testing Genomics / methods Humans Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 / genetics Neoplasms / genetics Prognosis Survival Rate
CNV LRRK2 cancer mutations prognostic

Journal

Genes
ISSN: 2073-4425
Titre abrégé: Genes (Basel)
Pays: Switzerland
ID NLM: 101551097

Informations de publication

Date de publication:
24 07 2020
Historique:
received: 15 06 2020
revised: 14 07 2020
accepted: 22 07 2020
entrez: 30 7 2020
pubmed: 30 7 2020
medline: 2 4 2021
Statut: epublish

Résumé

Genetic alterations of leucine-rich repeat kinase 2 (

Identifiants

DOI: 10.3390/genes11080846 PMID: 32722212 PMC: PMC7465025
pubmed: 32722212
pii: genes11080846
doi: 10.3390/genes11080846
pmc: PMC7465025
pii:
doi:

Substances chimiques

LRRK2 protein, human EC 2.7.11.1
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 EC 2.7.11.1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Références

Adv Neurobiol. 2017;14:241-264
pubmed: 28353288
Mov Disord. 2014 Sep;29(10):1325-6
pubmed: 25048644
Cancer Discov. 2012 May;2(5):401-4
pubmed: 22588877
BMC Syst Biol. 2018 Jan 10;12(1):3
pubmed: 29321020
Int J Cancer. 2013 May 1;132(9):2217-21
pubmed: 23047306
J Cell Physiol. 2019 Dec;234(12):22742-22752
pubmed: 31127628
Mol Brain. 2015 Sep 18;8:54
pubmed: 26384650
EMBO Rep. 2018 Jan 2;19(2):305-319
pubmed: 29295817
Front Cell Neurosci. 2017 May 11;11:125
pubmed: 28553204
Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1439-44
pubmed: 21220347
J Cancer. 2019 Jan 1;10(1):51-60
pubmed: 30662525
Lancet. 2005 Jan 29-Feb 4;365(9457):410-2
pubmed: 15680455
PLoS Genet. 2014 Feb 20;10(2):e1004173
pubmed: 24586201
Brain Behav. 2017 Dec 07;8(1):e00858
pubmed: 29568677
Biochem Soc Trans. 2019 Dec 20;47(6):1581-1595
pubmed: 31769472
Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):E4357-66
pubmed: 27357661
Mol Cancer. 2014 May 06;13:103
pubmed: 24885928
Lancet Oncol. 2012 Nov;13(11):1133-40
pubmed: 23084521
Biochem Soc Trans. 2017 Feb 8;45(1):155-162
pubmed: 28202669
J Clin Oncol. 2013 Jun 1;31(16):2024-8
pubmed: 23569312
J Neural Transm (Vienna). 2011 May;118(5):795-808
pubmed: 21552986
Lancet. 2005 Jan 29-Feb 4;365(9457):415-6
pubmed: 15680457
JCO Precis Oncol. 2017 Jul;2017:
pubmed: 28890946
Oncotarget. 2011 Nov;2(11):886-91
pubmed: 22095441
Neuron. 2004 Nov 18;44(4):595-600
pubmed: 15541308
Mov Disord. 2010 Nov 15;25(15):2536-41
pubmed: 20818610
FASEB J. 2016 Jan;30(1):336-47
pubmed: 26396237
Hum Mol Genet. 2009 Nov 1;18(21):4022-34
pubmed: 19640926
Mov Disord. 2019 Sep;34(9):1392-1398
pubmed: 31348549
Gastroenterol Clin Biol. 2010 Apr-May;34(4-5):255-9
pubmed: 20418034
Nat Med. 2015 Oct;21(10):1190-8
pubmed: 26366712
Oncogenesis. 2018 Mar 13;7(3):25
pubmed: 29540752
Mov Disord. 2014 May;29(6):750-5
pubmed: 24357540
Sci Transl Med. 2018 Jun 6;10(444):
pubmed: 29875204
PeerJ. 2015 Feb 19;3:e778
pubmed: 25737818
Int J Oncol. 2019 Jul;55(1):21-34
pubmed: 31180559
Nat Genet. 2008 Aug;40(8):955-62
pubmed: 18587394
Neurochem Res. 2014;39(3):576-92
pubmed: 23729298
Neurobiol Dis. 2018 Mar;111:26-35
pubmed: 29246723
Neuron. 2004 Nov 18;44(4):601-7
pubmed: 15541309
Nat Rev Neurol. 2020 Feb;16(2):97-107
pubmed: 31980808
J Neurochem. 1990 Mar;54(3):823-7
pubmed: 2154550
J Cell Physiol. 2020 Mar;235(3):3056-3068
pubmed: 31538341
N Engl J Med. 2009 Dec 31;361(27):2609-18
pubmed: 20018961
Lancet. 2005 Jan 29-Feb 4;365(9457):412-5
pubmed: 15680456
Ann Neurol. 2002 Mar;51(3):296-301
pubmed: 11891824
Curr Neuropharmacol. 2016;14(3):214-25
pubmed: 26517051
Neuroscience. 2008 Mar 18;152(2):429-36
pubmed: 18272292
Front Neurosci. 2020 Apr 28;14:376
pubmed: 32410948
Mol Neurodegener. 2019 Dec 21;14(1):49
pubmed: 31864390
Sci Transl Med. 2018 Jan 10;10(423):
pubmed: 29321258
Sci Signal. 2013 Apr 02;6(269):pl1
pubmed: 23550210
Oncogene. 2005 Apr 21;24(18):2929-43
pubmed: 15735718
Dig Dis Sci. 2020 Feb;65(2):500-508
pubmed: 31489563
Exp Cell Res. 2008 Jun 10;314(10):2055-65
pubmed: 18445495
Neurology. 2012 Mar 13;78(11):781-6
pubmed: 22323743
Adv Neurobiol. 2017;14:3-30
pubmed: 28353276
Expert Opin Ther Pat. 2020 Apr;30(4):275-286
pubmed: 32049564
Biochem Biophys Res Commun. 2013 Nov 29;441(4):862-6
pubmed: 24211199
Mov Disord. 2019 Apr;34(S1):S1-S19
pubmed: 30913575
Onco Targets Ther. 2018 Jan 31;11:609-618
pubmed: 29430186
J Cell Physiol. 2019 Nov;234(11):20980-20991
pubmed: 31102261

Auteurs

Gianluca Lopez (G)

Pathology Unit, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, 20122 Milan, Italy.
School of Pathology, University of Milan, 20122 Milan, Italy.

Giulia Lazzeri (G)

Neurology Unit, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Dino Ferrari Center, Neuroscience Section, Department of Pathophysiology and Transplantation, University of Milan, 20122 Milan, Italy.
School of Neurology, University of Milan, 20122 Milan, Italy.

Alessandra Rappa (A)

European Institute of Oncology (IEO), 20141 Milan, Italy.

Giuseppe Isimbaldi (G)

Unit of Surgical Pathology and Cytogenetics, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milan, Italy.

Fulvia Milena Cribiù (FM)

Pathology Unit, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, 20122 Milan, Italy.
ORCID: 0000-0002-4882-3204

Elena Guerini-Rocco (E)

European Institute of Oncology (IEO), 20141 Milan, Italy.
Department of Oncology and Hemato-oncology, University of Milan, 20122 Milan, Italy.

Stefano Ferrero (S)

Pathology Unit, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Department of Biomedical, Surgical, and Dental Sciences, University of Milan, 20122 Milan, Italy.

Valentina Vaira (V)

Pathology Unit, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, 20122 Milan, Italy.
ORCID: 0000-0003-4416-6216

Alessio Di Fonzo (A)

Neurology Unit, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Dino Ferrari Center, Neuroscience Section, Department of Pathophysiology and Transplantation, University of Milan, 20122 Milan, Italy.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Polymorphisme génétique › Variation structurale du génome › Variations de nombre de copies de segment d'ADN › Comprehensive Genomic Analysis Reveals the...
questionsmedicales.fr › Établissements, main d'oeuvre et services de soins de santé › Services de santé › Services de médecine préventive › Services de diagnostic › Dépistage génétique › Comprehensive Genomic Analysis Reveals the...
questionsmedicales.fr › Disciplines des sciences naturelles › Disciplines des sciences biologiques › Biologie › Génétique › Génomique › Comprehensive Genomic Analysis Reveals the...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Comprehensive Genomic Analysis Reveals the...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines associées à la maladie de Parkinson › Leucine-rich repeat serine-threonine protein kinase-2 › Comprehensive Genomic Analysis Reveals the...
questionsmedicales.fr › Tumeurs › Comprehensive Genomic Analysis Reveals the...
questionsmedicales.fr › Diagnostic › Pronostic › Comprehensive Genomic Analysis Reveals the...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Registre civil › Mortalité › Taux de survie › Comprehensive Genomic Analysis Reveals the...