The Hep-CORE policy score: A European hepatitis C national policy implementation ranking based on patient organization data.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2020
Historique:
received: 14 04 2020
accepted: 20 06 2020
entrez: 30 7 2020
pubmed: 30 7 2020
medline: 12 9 2020
Statut: epublish

Résumé

New hepatitis C virus (HCV) treatments spurred the World Health Organization (WHO) in 2016 to adopt a strategy to eliminate HCV as a public health threat by 2030. To achieve this, key policies must be implemented. In the absence of monitoring mechanisms, this study aims to assess the extent of policy implementation from the perspective of liver patient groups. Thirty liver patient organisations, each representing a country, were surveyed in October 2018 to assess implementation of HCV policies in practice. Respondents received two sets of questions based on: 1) WHO recommendations; and 2) validated data sources verifying an existing policy in their country. Academic experts selected key variables from each set for inclusion into policy scores. The similarity scores were calculated for each set with a multiple joint correspondence analysis. Proxy reference countries were included as the baseline to contextualize results. We extracted scores for each country and standardized them from 0 to 10 (best). Twenty-five countries responded. For the score based on WHO recommendations, Bulgaria had the lowest score whereas five countries (Cyprus, Netherlands, Portugal, Slovenia, and Sweden) had the highest scores. For the verified policy score, a two-dimensional solution was identified; first dimension scores pertained to whether verified policies were in place and second dimension scores pertained to the proportion of verified policies in-place that were implemented. Spain, UK, and Sweden had high scores for both dimensions. Patient groups reported that the European region is not on track to meet WHO 2030 HCV goals. More action should be taken to implement and monitor HCV policies.

Sections du résumé

BACKGROUND
New hepatitis C virus (HCV) treatments spurred the World Health Organization (WHO) in 2016 to adopt a strategy to eliminate HCV as a public health threat by 2030. To achieve this, key policies must be implemented. In the absence of monitoring mechanisms, this study aims to assess the extent of policy implementation from the perspective of liver patient groups.
METHODS
Thirty liver patient organisations, each representing a country, were surveyed in October 2018 to assess implementation of HCV policies in practice. Respondents received two sets of questions based on: 1) WHO recommendations; and 2) validated data sources verifying an existing policy in their country. Academic experts selected key variables from each set for inclusion into policy scores. The similarity scores were calculated for each set with a multiple joint correspondence analysis. Proxy reference countries were included as the baseline to contextualize results. We extracted scores for each country and standardized them from 0 to 10 (best).
RESULTS
Twenty-five countries responded. For the score based on WHO recommendations, Bulgaria had the lowest score whereas five countries (Cyprus, Netherlands, Portugal, Slovenia, and Sweden) had the highest scores. For the verified policy score, a two-dimensional solution was identified; first dimension scores pertained to whether verified policies were in place and second dimension scores pertained to the proportion of verified policies in-place that were implemented. Spain, UK, and Sweden had high scores for both dimensions.
CONCLUSIONS
Patient groups reported that the European region is not on track to meet WHO 2030 HCV goals. More action should be taken to implement and monitor HCV policies.

Identifiants

pubmed: 32722701
doi: 10.1371/journal.pone.0235715
pii: PONE-D-20-09886
pmc: PMC7386634
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0235715

Subventions

Organisme : Department of Health
ID : 14/02/17
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/P025064/1
Pays : United Kingdom
Organisme : Department of Health
ID : RP-2016-07-012
Pays : United Kingdom

Déclaration de conflit d'intérêts

The authors have read the journal's policies and declare the following competing interests: This study was directly funded by ELPA, who in turn were funded by AbbVie, Gilead Sciences, and Merck & Co. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

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Auteurs

Adam Palayew (A)

McGill University Department of Epidemiology, Biostatistics, and Occupational Health, Montreal, Quebec, Canada.

Samya R Stumo (SR)

Barcelona Institute for Global Health (ISGlobal), Hospital Clínic, University of Barcelona, Barcelona, Spain.

Graham S Cooke (GS)

Division of Infectious Diseases, Imperial College, London, United Kingdom.

Sharon J Hutchinson (SJ)

School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, United Kingdom.

Marie Jauffret-Roustide (M)

Cermes3 (Inserm U988/CNRS UMR 8211/Ecole des Hautes Etudes en Sciences Sociales/Paris Descartes University), Paris, France.

Mojca Maticic (M)

Clinic for Infectious Diseases and Febrile Illnesses, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.

Magdalena Harris (M)

Department of Public Health, Environments and Society, London School of Hygiene & Tropical Medicine, London, United Kingdom.

Ammal M Metwally (AM)

Community Medicine Research Department, Medicine Research Division, National Research Centre, Giza, Egypt.
Association of Liver Patient Care, Dakhlyia, Egypt.

Homie Razavi (H)

Center for Disease Analysis Foundation, Lafayette, CO, United States of America.

Jeffrey V Lazarus (JV)

Barcelona Institute for Global Health (ISGlobal), Hospital Clínic, University of Barcelona, Barcelona, Spain.

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Classifications MeSH