The associations of BMI with mean diffusivity of basal ganglia among young adults with mild obesity and without obesity.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
28 07 2020
28 07 2020
Historique:
received:
12
04
2019
accepted:
09
07
2020
entrez:
30
7
2020
pubmed:
30
7
2020
medline:
15
12
2020
Statut:
epublish
Résumé
Obesity causes a wide range of systemic diseases and is associated with mood and anxiety disorders. It is also associated with dopaminergic reward system function. However, the relationships between microstructural properties of the dopaminergic system and body mass index (BMI) have not been investigated. In this study, we investigated the associations of BMI with mean diffusivity (MD), diffusion tensor imaging measure in areas of the dopaminergic system (MDDS) in 435 healthy young adults with mild obesity and without obesity (BMI < 40). We detected the association between greater BMI and lower MD of the right globus pallidus and the right putamen. These results suggest that the property of the dopaminergic system is associated with BMI among young adults with mild obesity and without obesity.
Identifiants
pubmed: 32724120
doi: 10.1038/s41598-020-69438-5
pii: 10.1038/s41598-020-69438-5
pmc: PMC7387490
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
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