Early Insights From Clinical Trials of Typhoid Conjugate Vaccine.


Journal

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
ISSN: 1537-6591
Titre abrégé: Clin Infect Dis
Pays: United States
ID NLM: 9203213

Informations de publication

Date de publication:
29 07 2020
Historique:
entrez: 30 7 2020
pubmed: 30 7 2020
medline: 28 4 2021
Statut: ppublish

Résumé

Clinical trials of typhoid conjugate vaccine (TCV) are ongoing in 4 countries. Early data confirm safety, tolerability, and immunogenicity of typhoid conjugate vaccine, and early efficacy results are promising. These data support World Health Organization recommendations and planned country introductions. Forthcoming trial data will continue to inform programmatic use of typhoid conjugate vaccine.

Identifiants

pubmed: 32725230
pii: 5877827
doi: 10.1093/cid/ciaa370
pmc: PMC7388715
doi:

Substances chimiques

Typhoid-Paratyphoid Vaccines 0
Vaccines, Conjugate 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

S155-S159

Informations de copyright

© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America.

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Auteurs

Kathleen M Neuzil (KM)

University of Maryland School of Medicine, Baltimore, Maryland, USA.

Buddha Basnyat (B)

Oxford University Clinical Research Unit, Patan Academy of Health Sciences, Kathmandu, Nepal.

John D Clemens (JD)

Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.

Melita A Gordon (MA)

Malawi-Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi.
Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom.

Priyanka D Patel (PD)

Malawi-Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi.

Andrew J Pollard (AJ)

Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
National Institute for Health Research Oxford Biomedical Research Centre, Oxford, United Kingdom.

Mila Shakya (M)

Oxford University Clinical Research Unit, Patan Academy of Health Sciences, Kathmandu, Nepal.

Firdausi Qadri (F)

Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.

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Classifications MeSH