A Frequency-Selective pH-Responsive paraCEST Agent.


Journal

Angewandte Chemie (International ed. in English)
ISSN: 1521-3773
Titre abrégé: Angew Chem Int Ed Engl
Pays: Germany
ID NLM: 0370543

Informations de publication

Date de publication:
23 11 2020
Historique:
received: 06 07 2020
pubmed: 30 7 2020
medline: 20 3 2021
entrez: 30 7 2020
Statut: ppublish

Résumé

Paramagnetic chemical exchange saturation transfer (paraCEST) agents are well-suited for imaging tissue pH because the basis of CEST, chemical exchange, is inherently sensitive to pH. Several previous pH-sensitive paraCEST agents were based on an exchanging Ln

Identifiants

pubmed: 32726500
doi: 10.1002/anie.202008888
pmc: PMC7719596
mid: NIHMS1642100
doi:

Substances chimiques

Contrast Media 0
Coordination Complexes 0
Lanthanoid Series Elements 0
Ligands 0
Luminescent Agents 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

21671-21676

Subventions

Organisme : U.S. Department of Health and Human Services
ID : CA-115531
Pays : International
Organisme : NIBIB NIH HHS
ID : P41 EB015908
Pays : United States
Organisme : NIH HHS
ID : S10 OD023552
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA115531
Pays : United States
Organisme : NIBIB NIH HHS
ID : EB-02584
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL133506
Pays : United States

Informations de copyright

© 2020 Wiley-VCH GmbH.

Références

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Auteurs

S James Ratnakar (SJ)

Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Sara Chirayil (S)

Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Alexander M Funk (AM)

Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Shanrong Zhang (S)

Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.

João F Queiró (JF)

CMUC, Department of Mathematics, University of Coimbra, Coimbra, Portugal.

Carlos F G C Geraldes (CFGC)

Department of Life Sciences and Coimbra Chemistry Center, University of Coimbra, Coimbra, Portugal.
CIBIT- Coimbra Institute for Biomedical Imaging and Translational Research, University of Coimbra, Coimbra, Portugal.

Zoltan Kovacs (Z)

Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.

A Dean Sherry (AD)

Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Department of Chemistry and Biochemistry, University of Texas at Dallas, Richardson, TX, USA.

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Classifications MeSH