Identifying research priorities for the study of atypical anorexia nervosa: A Delphi study.

body mass index feeding and eating disorders interdisciplinary research obesity overweight stereotyping

Journal

The International journal of eating disorders
ISSN: 1098-108X
Titre abrégé: Int J Eat Disord
Pays: United States
ID NLM: 8111226

Informations de publication

Date de publication:
10 2020
Historique:
received: 09 06 2020
revised: 11 07 2020
accepted: 12 07 2020
pubmed: 1 8 2020
medline: 7 4 2021
entrez: 1 8 2020
Statut: ppublish

Résumé

Individuals meeting all criteria for anorexia nervosa (AN) except that weight falls within or above the normal range despite significant weight loss are categorized as having atypical AN (AAN). Existing research has provided mixed evidence concerning the diagnostic demarcation of AN and AAN. The aim of the present study was to identify research priorities for furthering the understanding of AN and AAN as diagnostic entities. Employing the Delphi methodology, experts in the field were invited to suggest research questions that need to be explored in the demarcation of AN from AAN. This yielded 24 research areas, that were presented in subsequent rounds where panelists were asked to prioritize areas of primary interest. Fifty-three panelists completed all three Delphi rounds. Consensus was only reached on three items considered to be of primary interest: medical, neurobiological, and neurological factors; epidemiology and natural course; and treatment response in AAN compared to AN. In contrast, questions of premorbid weight and determining the need for and nature of a body mass index cutoff differentiating between AAN and AN were seen as being of low priority. These findings reveal a relatively low degree of consensus on the demarcation of AN from AAN in the field of eating disorders. A reason could be that the definition and use of the AAN category vary in research and clinical practice. In order to achieve further diagnostic clarity, research on the demarcation of AAN and AN should focus on the identified prioritized research areas.

Identifiants

pubmed: 32735068
doi: 10.1002/eat.23358
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1729-1738

Subventions

Organisme : NIMH NIH HHS
ID : R01MH119084
Pays : United States
Organisme : NIMH NIH HHS
ID : R01MH120170
Pays : United States

Informations de copyright

© 2020 The Authors. International Journal of Eating Disorders published by Wiley Periodicals LLC.

Références

American Psychiatric Association. (1994). DSM-IV: Diagnostic and Statistical Manual of Mental Illness (4th ed.). Washington, D.C: American Psychiatry Publishing.
American Psychiatric Association. (2013). DSM-5: Diagnostic and Statistical Manual of Mental Illness (5th ed.). Washington, DC: American Psychiatry Publishing.
Birgegård, A., Groß, G., de Man Lapidoth, J., & Norring, C. (2013). DSM-5: Problems and suggestions. Journal of Eating Disorders, 1(1), 8. https://doi.org/10.1186/2050-2974-1-8
Breithaupt, L., Hübel, C., & Bulik, C. M. (2018). Updates on genome-wide association findings in eating disorders and future application to precision medicine. Current Neuropharmacology, 16, 1102-1110. https://doi.org/10.2174/1570159X16666180222163450
Buchman, S., Attia, E., Dawson, L., & Steinglass, J. E. (2019). Steps of care for adolescents with anorexia nervosa-A Delphi study. International Journal of Eating Disorders, 52(7), 777-785. https://doi.org/10.1002/eat.23088
Bulik, C. M., Kleiman, S. C., & Yilmaz, Z. (2016). Genetic epidemiology of eating disorders. Current Opinion in Psychiatry, 29(6), 383-388. https://doi.org/10.1097/YCO.0000000000000275
Ciciurkaite, G., & Perry, B. L. (2018). Body weight, perceived weight stigma and mental health among women at the intersection of race/ethnicity and socioeconomic status: Insights from the modified labelling approach. Sociology of Health & Illness, 40(1), 18-37. https://doi.org/10.1111/1467-9566.12619
Dennett, C. (2019, February 20). Anorexia knows no body type - and thinking otherwise can be a barrier to treatment. Seattle Times.
Feighner, J. P., Robins, E., Guze, S. B., Woodruff, R. A. J., Winokur, G., & Munoz, R. (1972). Diagnostic criteria for use in psychiatric research. Archives of General Psychiatry, 26(1), 57-63. Retrieved from. https://doi.org/10.1001/archpsyc.1972.01750190059011
Forman, S. F., McKenzie, N., Hehn, R., Monge, M. C., Kapphahn, C. J., Mammel, K. A., … Woods, E. R. (2014). Predictors of outcome at 1 year in adolescents with DSM-5 restrictive eating disorders: Report of the National Eating Disorders Quality Improvement Collaborative. Journal of Adolescent Health, 55(6), 750-756. https://doi.org/10.1016/j.jadohealth.2014.06.014
Forney, K. J., Brown, T. A., Holland-Carter, L. A., Kennedy, G. A., & Keel, P. K. (2017). Defining “significant weight loss” in atypical anorexia nervosa. International Journal of Eating Disorders, 50(8), 952-962. https://doi.org/10.1002/eat.22717
Gorwood, P., Duriez, P., Lengvenyte, A., Guillaume, S., & Criquillion, S. (2019). Clinical insight in anorexia nervosa: Associated and predictive factors. Psychiatry Research, 281, 112561. https://doi.org/10.1016/j.psychres.2019.112561
Hasson, F., Keeney, S., & McKenna, H. (2000). Research guidelines for the Delphi survey technique. Journal of Advanced Nursing, 32(4), 1008-1015. https://doi.org/10.1046/j.1365-2648.2000.t01-1-01567.x
Helmer-Hirschberg, O. (1967). Analysis of the Future: The Delphi Method. https://www.rand.org/pubs/papers/P3558.html
Hsieh, H.-F., & Shannon, S. E. (2005). Three approaches to qualitative content analysis. Qualitative Health Research, 15(9), 1277-1288. https://doi.org/10.1177/1049732305276687
Hsu, C.-C., & Sanford, B. A. (2007). The Delphi technique: Making sense of consensus. Practical Assessment, Research & Evaluation, 12(10), 1-8.
Hübel, C., Gaspar, H. A., Coleman, J. R. I., Finucane, H., Purves, K. L., Hanscombe, K. B., … Breen, G. (2019). Genomics of body fat percentage may contribute to sex bias in anorexia nervosa. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 180(6), 428-438. https://doi.org/10.1002/ajmg.b.32709
Hughes, E. K., Le Grange, D., Court, A., & Sawyer, S. M. (2017). A case series of family-based treatment for adolescents with atypical anorexia nervosa. International Journal of Eating Disorders, 50(4), 424-432. https://doi.org/10.1002/eat.22662
Keeney, S., Hasson, F., & McKenna, H. (2006). Consulting the oracle: Ten lessons from using the Delphi technique in nursing research. Journal of Advanced Nursing, 53(2), 205-212. https://doi.org/10.1111/j.1365-2648.2006.03716.x
Konstantakopoulos, G., Tchanturia, K., Surguladze, S. A., & David, A. S. (2011). Insight in eating disorders: Clinical and cognitive correlates. Psychological Medicine, 41(9), 1951-1961. https://doi.org/10.1017/S0033291710002539
Lebow, J., Sim, L. A., & Kransdorf, L. N. (2015). Prevalence of a history of overweight and obesity in adolescents with restrictive eating disorders. Journal of Adolescent Health, 56(1), 19-24. https://doi.org/10.1016/j.jadohealth.2014.06.005
Lebow, J., Sim, L., Crosby, R. D., Goldschmidt, A. B., Le Grange, D., & Accurso, E. C. (2019). Weight gain trajectories during outpatient family-based treatment for adolescents with anorexia nervosa. International Journal of Eating Disorders, 52(1), 88-94. https://doi.org/10.1002/eat.23000
Mittnacht, A. M., & Bulik, C. M. (2015). Best nutrition counseling practices for the treatment of anorexia nervosa: A Delphi study. International Journal of Eating Disorders, 48(1), 111-122. https://doi.org/10.1002/eat.22319
Nagata, J. M., Garber, A. K., & Buckelew, S. M. (2018). Weight restoration in atypical anorexia nervosa: A clinical conundrum. International Journal of Eating Disorders, 51(11), 1290-1293. https://doi.org/10.1002/eat.22953
Neumark-Sztainer, D. (2009). The interface between the eating disorders and obesity fields: Moving toward a model of shared knowledge and collaboration. Eating and Weight Disorders, 14(1), 51-58. https://doi.org/10.1007/BF03327795
Neumark-Sztainer, D. (2015). Higher weight status and restrictive eating disorders: An overlooked concern. Journal of Adolescent Health, 56(1), 1-2. https://doi.org/10.1016/j.jadohealth.2014.10.261
Noetel, M., Dawson, L., Hay, P., & Touyz, S. (2017). The assessment and treatment of unhealthy exercise in adolescents with anorexia nervosa: A Delphi study to synthesize clinical knowledge. International Journal of Eating Disorders, 50(4), 378-388. https://doi.org/10.1002/eat.22657
Olivo, G., Solstrand Dahlberg, L., Wiemerslage, L., Swenne, I., Zhukovsky, C., Salonen-Ros, H., … Schiöth, H. B. (2018). Atypical anorexia nervosa is not related to brain structural changes in newly diagnosed adolescent patients. International Journal of Eating Disorders, 51(1), 39-45. https://doi.org/10.1002/eat.22805
Olivo, G., Swenne, I., Zhukovsky, C., Tuunainen, A.-K., Saaid, A., Salonen-Ros, H., … Schiöth, H. B. (2019). Preserved white matter microstructure in adolescent patients with atypical anorexia nervosa. International Journal of Eating Disorders, 52(2), 166-174. https://doi.org/10.1002/eat.23012
Olivo, G., Zhukovsky, C., Salonen-Ros, H., Larsson, E.-M., Brooks, S., & Schiöth, H. B. (2019). Functional connectivity underlying hedonic response to food in female adolescents with atypical AN: The role of somatosensory and salience networks. Translational Psychiatry, 9(1), 276. https://doi.org/10.1038/s41398-019-0617-0
Powell, C. (2003). The Delphi technique: Myths and realities. Journal of Advanced Nursing, 41(4), 376-382. https://doi.org/10.1046/j.1365-2648.2003.02537.x
Sawyer, S. M., Whitelaw, M., Le Grange, D., Yeo, M., & Hughes, E. K. (2016). Physical and psychological morbidity in adolescents with atypical anorexia nervosa. Pediatrics, 137(4), e20154080. https://doi.org/10.1542/peds.2015-4080
Schorr, M., Drabkin, A., Rothman, M. S., Meenaghan, E., Lashen, G. T., Mascolo, M., … Miller, K. K. (2019). Bone mineral density and estimated hip strength in men with anorexia nervosa, atypical anorexia nervosa and avoidant/restrictive food intake disorder. Clinical Endocrinology, 90(6), 789-797. https://doi.org/10.1111/cen.13960
Silén, Y., Raevuori, A., Jüriloo, E., Tainio, V.-M., Marttunen, M., & Keski-Rahkonen, A. (2015). Typical versus atypical anorexia nervosa among adolescents: Clinical characteristics and implications for ICD-11. European Eating Disorders Review, 23(5), 345-351. https://doi.org/10.1002/erv.2370
Sim, L. A., Lebow, J., & Billings, M. (2013). Eating disorders in adolescents with a history of obesity. Pediatrics, 132(4), e1026-e1030. https://doi.org/10.1542/peds.2012-3940
Sinha, I. P., Smyth, R. L., & Williamson, P. R. (2011). Using the Delphi technique to determine which outcomes to measure in clinical trials: Recommendations for the future based on a systematic review of existing studies. PLoS Medicine, 8(1), 1-5. https://doi.org/10.1371/journal.pmed.1000393
Steinglass, J. E., Glasofer, D. R., Dalack, M., & Attia, E. (2020). Between wellness, relapse, and remission: Stages of illness in anorexia nervosa. International Journal of Eating Disorders, 53, 1088-1096. https://doi.org/10.1002/eat.23237
Tait, A. (2015). When you're both overweight and anorexic. Retrieved March 1, 2019, from Broadly website: https://broadly.vice.com/en_us/article/gvz7m7/when-youre-both-overweight-and-anorexic
Trainer, S., Brewis, A., Hruschka, D., & Williams, D. (2015). Translating obesity: Navigating the front lines of the “war on fat.”. American Journal of Human Biology, 27(1), 61-68. https://doi.org/10.1002/ajhb.22623
Watson, H. J., Yilmaz, Z., Thornton, L. M., Hübel, C., Coleman, J. R. I., Gaspar, H. A., … Consortium, E. D. W. G. of the P. G. (2019). Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa. Nature Genetics, 51(8), 1207-1214. https://doi.org/10.1038/s41588-019-0439-2
Whitelaw, M., Gilbertson, H., Lee, K. J., & Sawyer, S. M. (2014). Restrictive eating disorders among adolescent inpatients. Pediatrics, 134(3), e758-e764. https://doi.org/10.1542/peds.2014-0070
Whitelaw, M., Lee, K. J., Gilbertson, H., & Sawyer, S. M. (2018). Predictors of complications in anorexia nervosa and atypical anorexia nervosa: Degree of underweight or extent and recency of weight loss? Journal of Adolescent Health, 63(6), 717-723. https://doi.org/10.1016/j.jadohealth.2018.08.019
World Health Organization. (2004). ICD-10: International statistical classification of diseases and related health problems, 10th revision (2nd ed.). Geneva, Switzerland: World Health Organization.

Auteurs

Mattias Strand (M)

Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Stockholm, Sweden.

Johan Zvrskovec (J)

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Social Genetic and Developmental Psychiatric Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Christopher Hübel (C)

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Social Genetic and Developmental Psychiatric Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
UK National Institute for Health Research (NIHR) Biomedical Research Centre for Mental Health, South London and Maudsley Hospital, London, UK.
National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark.

Christine M Peat (CM)

Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Cynthia M Bulik (CM)

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Andreas Birgegård (A)

Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Stockholm, Sweden.
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH