Prediction of distant metastases in patients with squamous cell carcinoma of head and neck using DWI and DCE-MRI.

diffusion weighted imaging distant metastases dynamic contrast enhanced-MRI intracellular water life time squamous cell carcinoma of head and neck volume transfer constant

Journal

Head & neck
ISSN: 1097-0347
Titre abrégé: Head Neck
Pays: United States
ID NLM: 8902541

Informations de publication

Date de publication:
11 2020
Historique:
received: 08 11 2019
revised: 30 05 2020
accepted: 26 06 2020
pubmed: 2 8 2020
medline: 22 6 2021
entrez: 2 8 2020
Statut: ppublish

Résumé

The primary purpose was to evaluate the prognostic potential of diffusion imaging (DWI) and dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) in predicting distant metastases in squamous cell carcinoma of head and neck (HNSCC) patients. The secondary aim was to examine differences in DWI and DCE-MRI-derived parameters on the basis of human papilloma virus (HPV) status, differentiation grade, and nodal stage of HNSCC. Fifty-six patients underwent pretreatment DWI and DCE-MRI. Patients were divided into groups who subsequently did (n = 12) or did not develop distant metastases (n = 44). Median values of apparent diffusion coefficient (ADC), volume transfer constant (K Lower but not significantly different K Pretreatment DCE-MRI may be useful in predicting distant metastases in HNSCC.

Sections du résumé

BACKGROUND
The primary purpose was to evaluate the prognostic potential of diffusion imaging (DWI) and dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) in predicting distant metastases in squamous cell carcinoma of head and neck (HNSCC) patients. The secondary aim was to examine differences in DWI and DCE-MRI-derived parameters on the basis of human papilloma virus (HPV) status, differentiation grade, and nodal stage of HNSCC.
METHODS
Fifty-six patients underwent pretreatment DWI and DCE-MRI. Patients were divided into groups who subsequently did (n = 12) or did not develop distant metastases (n = 44). Median values of apparent diffusion coefficient (ADC), volume transfer constant (K
RESULTS
Lower but not significantly different K
CONCLUSION
Pretreatment DCE-MRI may be useful in predicting distant metastases in HNSCC.

Identifiants

pubmed: 32737951
doi: 10.1002/hed.26386
doi:

Substances chimiques

Contrast Media 0

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

3295-3306

Subventions

Organisme : NIH HHS
ID : R01-CA102756 2004
Pays : United States

Informations de copyright

© 2020 Wiley Periodicals LLC.

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Auteurs

Sanjeev Chawla (S)

Department of Radiology, Perelman School of Medicine, the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Sungheon G Kim (SG)

Department of Radiology, Perelman School of Medicine, the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Department of Radiology, New York University Langone Medical Center, New York, New York, USA.

Laurie A Loevner (LA)

Department of Radiology, Perelman School of Medicine, the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Sumei Wang (S)

Department of Radiology, Perelman School of Medicine, the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Suyash Mohan (S)

Department of Radiology, Perelman School of Medicine, the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Alexander Lin (A)

Department of Radiation Oncology, Perelman School of Medicine, the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Harish Poptani (H)

Department of Radiology, Perelman School of Medicine, the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Department of Cellular and Molecular Physiology, University of Liverpool, Liverpool, UK.

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