A rapid and convenient screening method for detection of restricted monensin, decoquinate, and lasalocid in animal feed by applying SERS and chemometrics.
Antimicrobials
Chemometrics
Food safety
Gold nanoparticles
Surface-enhanced Raman spectroscopy (SERS)
Journal
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
ISSN: 1873-6351
Titre abrégé: Food Chem Toxicol
Pays: England
ID NLM: 8207483
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
04
06
2020
revised:
03
07
2020
accepted:
17
07
2020
pubmed:
2
8
2020
medline:
22
5
2021
entrez:
2
8
2020
Statut:
ppublish
Résumé
The surface-enhanced activities of size- and shape-controlled gold nanoparticles (AuNPs) with superior chemical stability were investigated to explore a possible development of a simple and non-destructive spectroscopic method to help the regulatory agency's analytical services for rapid detection and characterization of selected antimicrobials in animal feeds. Feed samples spiked at different concentration ranges of antimicrobials were evaluated using AuNPs as a surface-enhanced Raman spectroscopy (SERS) agent. The collected SERS spectra were mathematically preprocessed for further analysis. The classification models obtained 100% predictive accuracy with zero or little misclassification. The first two canonical variables (p = 0.001) could explain >95% of the variability in preprocessed spectral data. Most chemometric models for predicting MON, DEC, and LAS concentrations showed a high predictive accuracy (r
Identifiants
pubmed: 32738374
pii: S0278-6915(20)30523-8
doi: 10.1016/j.fct.2020.111633
pii:
doi:
Substances chimiques
Anti-Infective Agents
0
Decoquinate
534I52PVWH
Gold
7440-57-5
Monensin
906O0YJ6ZP
Lasalocid
W7V2ZZ2FWB
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
111633Informations de copyright
Published by Elsevier Ltd.