Isolation, structural elucidation, and immunoregulation properties of an arabinofuranan from the rinds of Garcinia mangostana.

Animals Cell Survival / drug effects Cytokines / metabolism Garcinia mangostana / chemistry Immunologic Factors / chemistry Macrophages / drug effects Mice Molecular Weight Monosaccharides Nitric Oxide / metabolism Plant Extracts / chemistry Polysaccharides / chemistry RAW 264.7 Cells Reactive Oxygen Species / metabolism Signal Transduction / drug effects Zebrafish / metabolism
2', 7'-dichlorofluorescein diacetate (PubChem CID: 104913) 3-amino, 4-aminomethyl-2′, 7′-difluorescein diacetate (PubChem CID: 2762646) Conformational analysis Dimethyl sulfoxide (PubChem CID: 679) GC–MS Garcinia mangostana L. Immunoregulation Macrophages Methyl iodide (PubChem CID: 6328) NMR Penicillin (PubChem CID: 2349) Polysaccharide Sodium borohydride (PubChem CID: 4311764) Sodium chloride (PubChem CID: 5234) Streptomycin (PubChem CID: 19649) Tricaine (PubChem CID: 261501) Trifluoroacetic acid (PubChem CID: 6422) Zebrafish embryo

Journal

Carbohydrate polymers
ISSN: 1879-1344
Titre abrégé: Carbohydr Polym
Pays: England
ID NLM: 8307156

Informations de publication

Date de publication:
15 Oct 2020
Historique:
received: 20 03 2020
revised: 01 06 2020
accepted: 01 06 2020
entrez: 5 8 2020
pubmed: 5 8 2020
medline: 7 4 2021
Statut: ppublish

Résumé

In our search for bioactive polysaccharides as immunomodulatory agents, an arabinofuranan (GMP90-1) was purified and characterized from the rinds of Garcinia mangostana L. GMP90-1 (absolute molecular weight: 5.30 × 10

Identifiants

DOI: 10.1016/j.carbpol.2020.116567 PMID: 32747240
pubmed: 32747240
pii: S0144-8617(20)30741-4
doi: 10.1016/j.carbpol.2020.116567
pii:
doi:

Substances chimiques

Cytokines 0
Immunologic Factors 0
Monosaccharides 0
Plant Extracts 0
Polysaccharides 0
Reactive Oxygen Species 0
Nitric Oxide 31C4KY9ESH

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

116567

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors have no conflicts of interest.

Auteurs

Shaojie Zhang (S)

State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China.

Zhengguo Li (Z)

State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China.

Xuelian Wang (X)

State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China.

Lijun An (L)

State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China.

Jiahe Bao (J)

State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China.

Jie Zhang (J)

Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan, School of Chemistry and Chemical Engineering, Shihezi University, Shihezi 832003, People's Republic of China.

Jianlin Cui (J)

School of Medicine, Nankai University, Tianjin 300071, People's Republic of China.

Yuhao Li (Y)

School of Medicine, Nankai University, Tianjin 300071, People's Republic of China.

Da-Qing Jin (DQ)

School of Medicine, Nankai University, Tianjin 300071, People's Republic of China.

Muhetaer Tuerhong (M)

College of Chemistry and Environmental Sciences, Laboratory of Xinjiang Native Medicinal and Edible Plant Resources Chemistry, Kashgar University, Kashgar 844000, People's Republic of China.

Munira Abudukeremu (M)

College of Chemistry and Environmental Sciences, Laboratory of Xinjiang Native Medicinal and Edible Plant Resources Chemistry, Kashgar University, Kashgar 844000, People's Republic of China.

Yasushi Ohizumi (Y)

Kansei Fukushi Research Institute, Tohoku Fukushi University, Sendai 989-3201, Japan.

Jing Xu (J)

State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China. Electronic address: xujing611@nankai.edu.cn.

Yuanqiang Guo (Y)

State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China. Electronic address: victgyq@nankai.edu.cn.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Isolation, structural elucidation, and...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Survie cellulaire › Isolation, structural elucidation, and...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Isolation, structural elucidation, and...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Rosanae › Clusiaceae › Garcinia › Garcinia mangostana › Isolation, structural elucidation, and...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Facteurs immunologiques › Isolation, structural elucidation, and...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Phagocytes › Macrophages › Isolation, structural elucidation, and...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Isolation, structural elucidation, and...
questionsmedicales.fr › Phénomènes chimiques › Masse moléculaire › Isolation, structural elucidation, and...
questionsmedicales.fr › Glucides › Sucres › Oses › Isolation, structural elucidation, and...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Oxydes d'azote › Monoxyde d'azote › Isolation, structural elucidation, and...
questionsmedicales.fr › Préparations pharmaceutiques › Extraits de plantes › Isolation, structural elucidation, and...
questionsmedicales.fr › Glucides › Polyosides › Isolation, structural elucidation, and...
questionsmedicales.fr › Cellules › Cellules RAW 264.7 › Isolation, structural elucidation, and...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Espèces réactives de l'oxygène › Isolation, structural elucidation, and...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Isolation, structural elucidation, and...
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