Ubiquitination of MHC Class II Is Required for Development of Regulatory but Not Conventional CD4

Animals Antigen Presentation / immunology CD4-Positive T-Lymphocytes / immunology Dendritic Cells / immunology Epithelial Cells / immunology Female Histocompatibility Antigens Class II / immunology Male Mice Mice, Inbred C57BL Spleen / immunology T-Lymphocytes, Regulatory / immunology Thymus Gland / immunology Ubiquitin / immunology Ubiquitin-Protein Ligases / immunology Ubiquitination / immunology

Journal

Journal of immunology (Baltimore, Md. : 1950)
ISSN: 1550-6606
Titre abrégé: J Immunol
Pays: United States
ID NLM: 2985117R

Informations de publication

Date de publication:
01 09 2020
Historique:
received: 05 11 2019
accepted: 24 06 2020
pubmed: 5 8 2020
medline: 23 3 2021
entrez: 5 8 2020
Statut: ppublish

Résumé

MHC class II (MHC II) displays peptides at the cell surface, a process critical for CD4

Identifiants

DOI: 10.4049/jimmunol.1901328 PMID: 32747505
pubmed: 32747505
pii: jimmunol.1901328
doi: 10.4049/jimmunol.1901328
doi:

Substances chimiques

Histocompatibility Antigens Class II 0
Ubiquitin 0
Ubiquitin-Protein Ligases EC 2.3.2.27

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1207-1216

Informations de copyright

Copyright © 2020 by The American Association of Immunologists, Inc.

Auteurs

Haiyin Liu (H)

Department of Biochemistry and Molecular Biology, The University of Melbourne, Bio21 Molecular Science and Biotechnology Institute, Parkville, Victoria 3010, Australia.
ORCID: 0000-0003-3103-6949

Kayla R Wilson (KR)

Department of Biochemistry and Molecular Biology, The University of Melbourne, Bio21 Molecular Science and Biotechnology Institute, Parkville, Victoria 3010, Australia.
ORCID: 0000-0003-2023-7964

Patrick Schriek (P)

Department of Biochemistry and Molecular Biology, The University of Melbourne, Bio21 Molecular Science and Biotechnology Institute, Parkville, Victoria 3010, Australia.
ORCID: 0000-0002-0875-884X

Christophe Macri (C)

Department of Biochemistry and Molecular Biology, The University of Melbourne, Bio21 Molecular Science and Biotechnology Institute, Parkville, Victoria 3010, Australia.

Annabelle B Blum (AB)

Department of Biochemistry and Molecular Biology, The University of Melbourne, Bio21 Molecular Science and Biotechnology Institute, Parkville, Victoria 3010, Australia.
ORCID: 0000-0002-0034-3527

Lauren Francis (L)

Department of Biochemistry and Molecular Biology, The University of Melbourne, Bio21 Molecular Science and Biotechnology Institute, Parkville, Victoria 3010, Australia.

Melanie Heinlein (M)

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.
Department of Medical Biology, The University of Melbourne, Parkville, Victoria 3013, Australia.

Champa Nataraja (C)

Rheumatology Group, Centre for Inflammatory Diseases, School of Clinical Sciences at Monash Health, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria 3168, Australia; and.

James Harris (J)

Rheumatology Group, Centre for Inflammatory Diseases, School of Clinical Sciences at Monash Health, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria 3168, Australia; and.
ORCID: 0000-0002-5634-9637

Sarah A Jones (SA)

Rheumatology Group, Centre for Inflammatory Diseases, School of Clinical Sciences at Monash Health, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria 3168, Australia; and.

Daniel H D Gray (DHD)

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.
Department of Medical Biology, The University of Melbourne, Parkville, Victoria 3013, Australia.
ORCID: 0000-0002-8457-8242

Jose A Villadangos (JA)

Department of Biochemistry and Molecular Biology, The University of Melbourne, Bio21 Molecular Science and Biotechnology Institute, Parkville, Victoria 3010, Australia.
Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Victoria 3010, Australia.
ORCID: 0000-0001-6771-8891

Justine D Mintern (JD)

Department of Biochemistry and Molecular Biology, The University of Melbourne, Bio21 Molecular Science and Biotechnology Institute, Parkville, Victoria 3010, Australia; jmintern@unimelb.edu.au j.villadangos@unimelb.edu.au.
ORCID: 0000-0002-3797-8577

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Ubiquitination of MHC Class II Is Required for...
questionsmedicales.fr › Phénomènes du système immunitaire › Immunité › Immunité acquise › Immunité cellulaire › Présentation d'antigène › Ubiquitination of MHC Class II Is Required for...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Lymphocytes T CD4+ › Ubiquitination of MHC Class II Is Required for...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Système phagocytaire mononucléé › Cellules dendritiques › Ubiquitination of MHC Class II Is Required for...
questionsmedicales.fr › Cellules › Cellules épithéliales › Ubiquitination of MHC Class II Is Required for...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Isoantigènes › Antigènes d'histocompatibilité › Antigènes d'histocompatibilité de classe II › Ubiquitination of MHC Class II Is Required for...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Ubiquitination of MHC Class II Is Required for...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › Ubiquitination of MHC Class II Is Required for...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Système lymphatique › Tissu lymphoïde › Rate › Ubiquitination of MHC Class II Is Required for...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Sous-populations de lymphocytes T › Lymphocytes T régulateurs › Ubiquitination of MHC Class II Is Required for...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Système lymphatique › Tissu lymphoïde › Thymus (glande) › Ubiquitination of MHC Class II Is Required for...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Ubiquitines › Ubiquitine › Ubiquitination of MHC Class II Is Required for...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Ligases › Ubiquitin-protein ligase complexes › Ubiquitin-protein ligases › Ubiquitination of MHC Class II Is Required for...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Modification traductionnelle des protéines › Maturation post-traductionnelle des protéines › Ubiquitination › Ubiquitination of MHC Class II Is Required for...