The Benefits of Whole Genome Sequencing for Foodborne Outbreak Investigation from the Perspective of a National Reference Laboratory in a Smaller Country.

STEC Shiga toxin-producing Escherichia coli WGS food safety foodborne outbreak investigation surveillance whole genome sequencing

Journal

Foods (Basel, Switzerland)
ISSN: 2304-8158
Titre abrégé: Foods
Pays: Switzerland
ID NLM: 101670569

Informations de publication

Date de publication:
01 Aug 2020
Historique:
received: 14 07 2020
revised: 24 07 2020
accepted: 27 07 2020
entrez: 6 8 2020
pubmed: 6 8 2020
medline: 6 8 2020
Statut: epublish

Résumé

Gradually, conventional methods for foodborne pathogen typing are replaced by whole genome sequencing (WGS). Despite studies describing the overall benefits, National Reference Laboratories of smaller countries often show slower uptake of WGS, mainly because of significant investments required to generate and analyze data of a limited amount of samples. To facilitate this process and incite policy makers to support its implementation, a Shiga toxin-producing

Identifiants

pubmed: 32752159
pii: foods9081030
doi: 10.3390/foods9081030
pmc: PMC7466227
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Sciensano
ID : contract RP .Be READY
Organisme : Belgian Federal Public Service of Health, Food Chain Safety and Environment
ID : RF 17/6316 StEQIDEMIC.be

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Auteurs

Stéphanie Nouws (S)

Department of Expertise and service provision, Transversal activities in Applied Genomics, Sciensano, 1050 Brussels, Belgium.
Department of Information Technology, IDLab, imec, Ghent University, 9052 Ghent, Belgium.

Bert Bogaerts (B)

Department of Expertise and service provision, Transversal activities in Applied Genomics, Sciensano, 1050 Brussels, Belgium.
Department of Information Technology, IDLab, imec, Ghent University, 9052 Ghent, Belgium.

Bavo Verhaegen (B)

National Reference Laboratory for Shiga Toxin-Producing Escherichia coli (NRL-STEC), National Reference Laboratory for Foodborne Outbreaks (NRL-FBO), Department of Infectious diseases in humans, Foodborne Pathogens, Sciensano, 1050 Brussels, Belgium.

Sarah Denayer (S)

National Reference Laboratory for Shiga Toxin-Producing Escherichia coli (NRL-STEC), National Reference Laboratory for Foodborne Outbreaks (NRL-FBO), Department of Infectious diseases in humans, Foodborne Pathogens, Sciensano, 1050 Brussels, Belgium.

Florence Crombé (F)

Department of Microbiology and Infection Control, National Reference Center for Shiga Toxin-Producing Escherichia coli (NRC-STEC), Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), 1090 Brussels, Belgium.

Klara De Rauw (K)

Department of Microbiology and Infection Control, National Reference Center for Shiga Toxin-Producing Escherichia coli (NRC-STEC), Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), 1090 Brussels, Belgium.

Denis Piérard (D)

Department of Microbiology and Infection Control, National Reference Center for Shiga Toxin-Producing Escherichia coli (NRC-STEC), Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), 1090 Brussels, Belgium.

Kathleen Marchal (K)

Department of Information Technology, IDLab, imec, Ghent University, 9052 Ghent, Belgium.
Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.
Department of Genetics, University of Pretoria, Pretoria 0083, South Africa.

Kevin Vanneste (K)

Department of Expertise and service provision, Transversal activities in Applied Genomics, Sciensano, 1050 Brussels, Belgium.

Nancy H C Roosens (NHC)

Department of Expertise and service provision, Transversal activities in Applied Genomics, Sciensano, 1050 Brussels, Belgium.

Sigrid C J De Keersmaecker (SCJ)

Department of Expertise and service provision, Transversal activities in Applied Genomics, Sciensano, 1050 Brussels, Belgium.

Classifications MeSH