Heart and Lung Multimodality Imaging in COVID-19.


Journal

JACC. Cardiovascular imaging
ISSN: 1876-7591
Titre abrégé: JACC Cardiovasc Imaging
Pays: United States
ID NLM: 101467978

Informations de publication

Date de publication:
08 2020
Historique:
received: 09 04 2020
revised: 27 05 2020
accepted: 28 05 2020
entrez: 9 8 2020
pubmed: 9 8 2020
medline: 28 8 2020
Statut: ppublish

Résumé

The severe acute respiratory syndrome-coronavirus-2 outbreak has rapidly reached pandemic proportions and has become a major threat to global health. Although the predominant clinical feature of coronavirus disease-2019 (COVID-19) is an acute respiratory syndrome of varying severity, ranging from mild symptomatic interstitial pneumonia to acute respiratory distress syndrome, the cardiovascular system can be involved in several ways. As many as 40% of patients hospitalized with COVID-19 have histories of cardiovascular disease, and current estimates report a proportion of myocardial injury in patients with COVID-19 of up to 12%. Multiple pathways have been suggested to explain this finding and the related clinical scenarios, encompassing local and systemic inflammatory responses and oxygen supply-demand imbalance. From a clinical point of view, cardiac involvement during COVID-19 may present a wide spectrum of severity, ranging from subclinical myocardial injury to well-defined clinical entities (myocarditis, myocardial infarction, pulmonary embolism, and heart failure), whose incidence and prognostic implications are currently largely unknown because of a significant lack of imaging data. Integrated heart and lung multimodality imaging plays a central role in different clinical settings and is essential in the diagnosis, risk stratification, and management of patients with COVID-19. The aims of this review are to summarize imaging-oriented pathophysiological mechanisms of lung and cardiac involvement in COVID-19 and to provide a guide for integrated imaging assessment in these patients.

Identifiants

pubmed: 32762885
pii: S1936-878X(20)30477-0
doi: 10.1016/j.jcmg.2020.05.017
pmc: PMC7314453
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1792-1808

Informations de copyright

Copyright © 2020 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

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Auteurs

Eustachio Agricola (E)

Cardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute, Milan, Italy; School of Medicine, Vita-Salute San Raffaele University, Milan, Italy. Electronic address: agricola.eustachio@hsr.it.

Alessandro Beneduce (A)

School of Medicine, Vita-Salute San Raffaele University, Milan, Italy; Interventional Cardiology Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Antonio Esposito (A)

School of Medicine, Vita-Salute San Raffaele University, Milan, Italy; Experimental Imaging Center, Radiology Department, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Giacomo Ingallina (G)

Cardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute, Milan, Italy; School of Medicine, Vita-Salute San Raffaele University, Milan, Italy.

Diego Palumbo (D)

School of Medicine, Vita-Salute San Raffaele University, Milan, Italy; Experimental Imaging Center, Radiology Department, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Anna Palmisano (A)

School of Medicine, Vita-Salute San Raffaele University, Milan, Italy; Experimental Imaging Center, Radiology Department, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Francesco Ancona (F)

Cardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute, Milan, Italy; School of Medicine, Vita-Salute San Raffaele University, Milan, Italy.

Luca Baldetti (L)

School of Medicine, Vita-Salute San Raffaele University, Milan, Italy; Cardiac Intensive Care Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Matteo Pagnesi (M)

School of Medicine, Vita-Salute San Raffaele University, Milan, Italy; Cardiac Intensive Care Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Giulio Melisurgo (G)

School of Medicine, Vita-Salute San Raffaele University, Milan, Italy; Cardiothoracic Intensive Care Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Alberto Zangrillo (A)

School of Medicine, Vita-Salute San Raffaele University, Milan, Italy; Anesthesia and Intensive Care Unit, Anesthesia and Intensive Care Department, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Francesco De Cobelli (F)

School of Medicine, Vita-Salute San Raffaele University, Milan, Italy; Experimental Imaging Center, Radiology Department, IRCCS San Raffaele Scientific Institute, Milan, Italy.

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Classifications MeSH