Comparison of three nutritional scoring systems for outcomes after complete resection of non-small cell lung cancer.
Aged
Carcinoma, Non-Small-Cell Lung
/ epidemiology
Female
Geriatric Assessment
/ methods
Humans
Japan
/ epidemiology
Lung Neoplasms
/ epidemiology
Male
Malnutrition
/ diagnosis
Neoplasm Staging
Nutrition Assessment
Nutritional Status
Pneumonectomy
/ adverse effects
Postoperative Complications
/ diagnosis
Predictive Value of Tests
Preoperative Care
/ methods
Prognosis
Research Design
controlling nutritional status
geriatric nutritional risk index
non--small cell lung cancer
preoperative nutritional status
prognostic nutritional index
Journal
The Journal of thoracic and cardiovascular surgery
ISSN: 1097-685X
Titre abrégé: J Thorac Cardiovasc Surg
Pays: United States
ID NLM: 0376343
Informations de publication
Date de publication:
Oct 2021
Oct 2021
Historique:
received:
16
12
2019
revised:
09
06
2020
accepted:
10
06
2020
pubmed:
11
8
2020
medline:
1
10
2021
entrez:
11
8
2020
Statut:
ppublish
Résumé
Mounting evidence suggests that preoperative nutritional status can predict postoperative outcomes in patients with non-small cell lung cancer. However, a consensus on the optimal evaluation tool among the various nutritional assessment methods has not been reached. This study aimed at validating the predictive value of 3 nutritional scoring systems for clinical outcomes in patients with completely resected non-small cell lung cancer. We retrospectively reviewed the preoperative data of 475 consecutive patients with completely resected non-small cell lung cancer to assess the following 3 albumin-based nutritional methods: prognostic nutritional index, controlling nutritional status score, and geriatric nutritional risk index. Receiver operating characteristic curves of the prognostic nutritional index, controlling nutritional status score, and geriatric nutritional risk index identified the optimal cutoff values for predicting the postoperative complications as 47, 2, and 101, respectively. Stratification of patients using these cutoff values indicated a higher postoperative complication rate in the malnutrition group than in the group with proper nutrition (P < .05 for all nutritional assessment methods). Additionally, patients with malnutrition exhibited significantly lower 5-year overall and recurrence-free survivals, regardless of the assessment method (P < .05 for all 3 nutritional assessment methods). Multivariate analyses showed that all 3 nutritional parameters were independent prognostic factors for overall survival after lung resection. The 3 nutritional assessment methods we used were found to have high predictive values for postoperative complications and survival. Preoperative nutritional conditioning may improve the postoperative outcomes in patients with resectable non-small cell lung cancer.
Identifiants
pubmed: 32771232
pii: S0022-5223(20)31751-7
doi: 10.1016/j.jtcvs.2020.06.030
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1257-1268.e3Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
Copyright © 2020 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.