Cancer therapy and treatments during COVID-19 era.

Angiotensin-Converting Enzyme 2 Antineoplastic Agents / therapeutic use Antiviral Agents / therapeutic use Betacoronavirus / drug effects COVID-19 Comorbidity Coronavirus Infections / drug therapy Drug Repositioning Gene Expression Regulation Host-Pathogen Interactions / drug effects Humans Hydroxychloroquine / therapeutic use Neoplasms / drug therapy Pandemics Peptidyl-Dipeptidase A / genetics Pneumonia, Viral / drug therapy SARS-CoV-2 Signal Transduction / genetics Spike Glycoprotein, Coronavirus / antagonists & inhibitors Trace Elements / therapeutic use Vitamins / therapeutic use
COVID-19 Cancer Natural products Nutraceuticals Repurposing approved drugs

Journal

Advances in biological regulation
ISSN: 2212-4934
Titre abrégé: Adv Biol Regul
Pays: England
ID NLM: 101572336

Informations de publication

Date de publication:
08 2020
Historique:
received: 17 06 2020
accepted: 23 06 2020
entrez: 11 8 2020
pubmed: 11 8 2020
medline: 28 8 2020
Statut: ppublish

Résumé

The COVID-19 pandemic has put a serious strain on health treatments as well at the economies of many nations. Unfortunately, there is not currently available vaccine for SARS-Cov-2/COVID-19. Various types of patients have delayed treatment or even routine check-ups and we are adapting to a virtual world. In many cases, surgeries are delayed unless they are essential. This is also true with regards to cancer treatments and screening. Interestingly, some existing drugs and nutraceuticals have been screened for their effects on COVID-19. Certain FDA approved drugs, vitamin, natural products and trace minerals may be repurposed to treat or improve the prevention of COVID-19 infections and disease progression. This review article will summarize how the treatments of various cancer patients has changed during the COVID-19 era as well as discuss the promise of some existing drugs and other agents to be repurposed to treat this disease.

Identifiants

DOI: 10.1016/j.jbior.2020.100739 PMID: 32773105 PMC: PMC7319627
pubmed: 32773105
pii: S2212-4926(20)30050-6
doi: 10.1016/j.jbior.2020.100739
pmc: PMC7319627
pii:
doi:

Substances chimiques

Antineoplastic Agents 0
Antiviral Agents 0
Spike Glycoprotein, Coronavirus 0
Trace Elements 0
Vitamins 0
spike protein, SARS-CoV-2 0
Hydroxychloroquine 4QWG6N8QKH
Peptidyl-Dipeptidase A EC 3.4.15.1
ACE2 protein, human EC 3.4.17.23
Angiotensin-Converting Enzyme 2 EC 3.4.17.23

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

100739

Subventions

Organisme : NCI NIH HHS
ID : P30 CA008748
Pays : United States

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

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Auteurs

Shaw M Akula (SM)

Department of Microbiology and Immunology, Brody School of Medicine at East Carolina University, Greenville, NC, 27858, USA.

Stephen L Abrams (SL)

Department of Microbiology and Immunology, Brody School of Medicine at East Carolina University, Greenville, NC, 27858, USA.

Linda S Steelman (LS)

Department of Microbiology and Immunology, Brody School of Medicine at East Carolina University, Greenville, NC, 27858, USA.

Saverio Candido (S)

Department of Biomedical and Biotechnological Sciences-Oncological, Clinical and General Pathology Section, University of Catania, Catania, Italy; Research Center for Prevention, Diagnosis and Treatment of Cancer (PreDiCT), University of Catania, Catania, Italy.

Massimo Libra (M)

Department of Biomedical and Biotechnological Sciences-Oncological, Clinical and General Pathology Section, University of Catania, Catania, Italy; Research Center for Prevention, Diagnosis and Treatment of Cancer (PreDiCT), University of Catania, Catania, Italy.

Kvin Lerpiriyapong (K)

Center of Comparative Medicine and Pathology, Memorial Sloan-Kettering Cancer Center, Weill Cornell Medicine and the Hospital for Special Surgery, New York City, NY, USA.

Lucio Cocco (L)

Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, Bologna, Italy.

Giulia Ramazzotti (G)

Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, Bologna, Italy.

Stefano Ratti (S)

Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, Bologna, Italy.

Matilde Y Follo (MY)

Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, Bologna, Italy.

Alberto M Martelli (AM)

Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, Bologna, Italy.

William L Blalock (WL)

Istituto di Genetica Molecolare-Luigi Luca Cavalli Sforza, UOS Bologna, Consiglio Nazionale Delle Ricerche (IGM-CNR), Bologna, Italy; IRCCS, Istituto Ortopedico Rizzoli, Bologna, Italy.

Manuela Piazzi (M)

Istituto di Genetica Molecolare-Luigi Luca Cavalli Sforza, UOS Bologna, Consiglio Nazionale Delle Ricerche (IGM-CNR), Bologna, Italy; IRCCS, Istituto Ortopedico Rizzoli, Bologna, Italy.

Giuseppe Montalto (G)

Department of Health Promotion, Maternal and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy; Institute for Biomedical Research and Innovation, National Research Council (CNR), Palermo, Italy.

Melchiorre Cervello (M)

Institute for Biomedical Research and Innovation, National Research Council (CNR), Palermo, Italy.

Monica Notarbartolo (M)

Department of Biological, Chemical and Pharmaceutical Science and Technology (STEBICEF), University of Palermo, Palermo, Italy.

Jorg Basecke (J)

Sankt-Josefs Hospital, Krankenhausstrasse 13, 49661, Cloppenburg, Germany.

James A McCubrey (JA)

Department of Microbiology and Immunology, Brody School of Medicine at East Carolina University, Greenville, NC, 27858, USA. Electronic address: mccubreyj@ecu.edu.

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Classifications MeSH

questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Peptide hydrolases › Exopeptidases › Carboxypeptidases › Angiotensin-converting enzyme 2 › Cancer therapy and treatments during COVID-19 era.
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › Cancer therapy and treatments during COVID-19 era.
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiviraux › Cancer therapy and treatments during COVID-19 era.
questionsmedicales.fr › Virus › Virus à ARN › Virus à ARN à brin positif › Nidovirales › Coronaviridae › Coronavirus › Betacoronavirus › Cancer therapy and treatments during COVID-19 era.
questionsmedicales.fr › Maladies de l'appareil respiratoire › Infections de l'appareil respiratoire › Pneumopathie infectieuse › Pneumopathie virale › COVID-19 › Cancer therapy and treatments during COVID-19 era.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Facteurs épidémiologiques › Comorbidité › Cancer therapy and treatments during COVID-19 era.
questionsmedicales.fr › Infection › Maladies virales › Infections à virus à ARN › Infections à Nidovirales › Infections à Coronaviridae › Infections à coronavirus › Cancer therapy and treatments during COVID-19 era.
questionsmedicales.fr › Techniques d'investigation › Développement de médicament › Repositionnement des médicaments › Cancer therapy and treatments during COVID-19 era.
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Cancer therapy and treatments during COVID-19 era.
questionsmedicales.fr › Phénomènes biologiques › Interactions hôte-microbes › Interactions hôte-pathogène › Cancer therapy and treatments during COVID-19 era.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Cancer therapy and treatments during COVID-19 era.
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Quinoléines › Aminoquinoléines › Chloroquine › Hydroxychloroquine › Cancer therapy and treatments during COVID-19 era.
questionsmedicales.fr › Tumeurs › Cancer therapy and treatments during COVID-19 era.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Épidémies de maladies › Épidémies › Pandémies › Cancer therapy and treatments during COVID-19 era.
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Peptide hydrolases › Exopeptidases › Dipeptidyl-Peptidases and Tripeptidyl-Peptidases › Peptidyl-Dipeptidase A › Cancer therapy and treatments during COVID-19 era.
questionsmedicales.fr › Maladies de l'appareil respiratoire › Infections de l'appareil respiratoire › Pneumopathie infectieuse › Pneumopathie virale › Cancer therapy and treatments during COVID-19 era.
questionsmedicales.fr › Virus › Virus à ARN › Virus à ARN à brin positif › Nidovirales › Coronaviridae › Coronavirus › Betacoronavirus › Virus du SRAS › SARS-CoV-2 › Cancer therapy and treatments during COVID-19 era.
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Cancer therapy and treatments during COVID-19 era.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines virales › Protéines virales structurales › Protéines de l'enveloppe virale › Protéines de fusion virale › Glycoprotéine de spicule des coronavirus › Cancer therapy and treatments during COVID-19 era.
questionsmedicales.fr › Aliments et boissons › Aliments › Nutriments › Micronutriments › Oligoéléments › Cancer therapy and treatments during COVID-19 era.
questionsmedicales.fr › Aliments et boissons › Aliments › Nutriments › Micronutriments › Vitamines › Cancer therapy and treatments during COVID-19 era.