Targeted Radiation Therapy Can Treat Myxomatous Cerebral Aneurysms.
Myxoma
Myxomatous aneurysms
Neoplastic aneurysms
Radiation therapy
Radiosurgery
Journal
World neurosurgery
ISSN: 1878-8769
Titre abrégé: World Neurosurg
Pays: United States
ID NLM: 101528275
Informations de publication
Date de publication:
11 2020
11 2020
Historique:
received:
15
06
2020
revised:
02
08
2020
accepted:
03
08
2020
pubmed:
12
8
2020
medline:
27
4
2021
entrez:
12
8
2020
Statut:
ppublish
Résumé
Neoplastic cerebral aneurysms are rare presentations of cardiac myxomas. The natural history of such aneurysms is not well understood, and the optimal treatment strategy remains unclear. Clipping and coiling are effective, although can carry significant morbidity. Chemotherapy and radiation can theoretically be effective, although their clinical efficacy remains to be proven. Here we describe a patient with cardiac myxoma presenting with multiple progressively fusiform aneurysms. These aneurysms were noted to be growing during conservative monitoring given the eloquent location. Subsequently, the patient underwent multiple sessions of targeted radiation therapy, which lead to obliteration, shrinkage, or halting in growth of these aneurysms. Low-dose targeted radiation therapy can be safe and effective in treatment of neoplastic myxomatous aneurysms.
Sections du résumé
BACKGROUND
Neoplastic cerebral aneurysms are rare presentations of cardiac myxomas. The natural history of such aneurysms is not well understood, and the optimal treatment strategy remains unclear. Clipping and coiling are effective, although can carry significant morbidity. Chemotherapy and radiation can theoretically be effective, although their clinical efficacy remains to be proven.
CASE DESCRIPTION
Here we describe a patient with cardiac myxoma presenting with multiple progressively fusiform aneurysms. These aneurysms were noted to be growing during conservative monitoring given the eloquent location. Subsequently, the patient underwent multiple sessions of targeted radiation therapy, which lead to obliteration, shrinkage, or halting in growth of these aneurysms.
CONCLUSIONS
Low-dose targeted radiation therapy can be safe and effective in treatment of neoplastic myxomatous aneurysms.
Identifiants
pubmed: 32781141
pii: S1878-8750(20)31786-1
doi: 10.1016/j.wneu.2020.08.022
pii:
doi:
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
332-335Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.