A Five-Ingredient Nutritional Supplement and Home-Based Resistance Exercise Improve Lean Mass and Strength in Free-Living Elderly.
Aged
Anabolic Agents
/ therapeutic use
Body Composition
Body Fluid Compartments
Caseins
/ therapeutic use
Combined Modality Therapy
Creatine
/ therapeutic use
Dietary Supplements
Double-Blind Method
Exercise
Fatty Acids, Omega-3
/ therapeutic use
Humans
Male
Muscle Fibers, Fast-Twitch
Muscle Proteins
Muscle Strength
Muscle, Skeletal
/ drug effects
Quadriceps Muscle
Resistance Training
Sarcopenia
/ physiopathology
Self Care
Vitamin D
/ therapeutic use
Vitamins
Whey Proteins
/ therapeutic use
COVID-19
creatine
multi-ingredient supplement
omega-3
randomized clinical trial
resistance exercise
sarcopenia
vitamin D
whey
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
10 Aug 2020
10 Aug 2020
Historique:
received:
11
07
2020
revised:
01
08
2020
accepted:
03
08
2020
entrez:
14
8
2020
pubmed:
14
8
2020
medline:
26
8
2020
Statut:
epublish
Résumé
Old age is associated with lower physical activity levels, suboptimal protein intake, and desensitization to anabolic stimuli, predisposing for age-related muscle loss (sarcopenia). Although resistance exercise (RE) and protein supplementation partially protect against sarcopenia under controlled conditions, the efficacy of home-based, unsupervised RE (HBRE) and multi-ingredient supplementation (MIS) is largely unknown. In this randomized, placebo-controlled and double-blind trial, we examined the effects of HBRE/MIS on muscle mass, strength, and function in free-living, older men. Thirty-two sedentary men underwent twelve weeks of home-based resistance band training (3 d/week), in combination with daily intake of a novel five-nutrient supplement ('Muscle5'; M5,
Identifiants
pubmed: 32785021
pii: nu12082391
doi: 10.3390/nu12082391
pmc: PMC7468764
pii:
doi:
Substances chimiques
Anabolic Agents
0
Caseins
0
Fatty Acids, Omega-3
0
Muscle Proteins
0
Vitamins
0
Whey Proteins
0
Vitamin D
1406-16-2
Creatine
MU72812GK0
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : CIHR
ID : 143325
Pays : Canada
Organisme : CSRD VA
ID : 1
Pays : United States
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