EF-hands in Neuronal Calcium Sensor Downstream Regulatory Element Antagonist Modulator Demonstrate Submillimolar Affinity for Li

Binding Sites Calcium / metabolism Kv Channel-Interacting Proteins / metabolism Lithium Protein Binding
EF-hands Neuronal calcium sensors downstream regulatory element antagonist modulator lithium potassium channel interacting proteins

Journal

ACS chemical neuroscience
ISSN: 1948-7193
Titre abrégé: ACS Chem Neurosci
Pays: United States
ID NLM: 101525337

Informations de publication

Date de publication:
02 09 2020
Historique:
pubmed: 14 8 2020
medline: 22 6 2021
entrez: 14 8 2020
Statut: ppublish

Résumé

Lithium has been used for the treatment of mood disorders for decades though the molecular mechanism of its therapeutic action and intracellular targets remain furtive. We report that neurotropic agent Li

Identifiants

DOI: 10.1021/acschemneuro.0c00399 PMID: 32786300
pubmed: 32786300
doi: 10.1021/acschemneuro.0c00399
doi:

Substances chimiques

Kv Channel-Interacting Proteins 0
Lithium 9FN79X2M3F
Calcium SY7Q814VUP

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2543-2548

Auteurs

Samiol Azam (S)

Nisha Bhattarai (N)

ORCID: 0000-0002-5595-1474

Adriana Riveron (A)

Sasha Rodriguez (S)

Prem P Chapagain (PP)

ORCID: 0000-0002-0999-4975

Jaroslava Miksovska (J)

ORCID: 0000-0002-0385-9457

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Classifications MeSH

questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Sites de fixation › EF-hands in Neuronal Calcium Sensor Downstream...
questionsmedicales.fr › Facteurs biologiques › Facteurs de la coagulation sanguine › Calcium › EF-hands in Neuronal Calcium Sensor Downstream...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › Protéines neuronales sensibles au calcium › Protéines KChIP › EF-hands in Neuronal Calcium Sensor Downstream...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux légers › Lithium › EF-hands in Neuronal Calcium Sensor Downstream...
questionsmedicales.fr › Métabolisme › Liaison aux protéines › EF-hands in Neuronal Calcium Sensor Downstream...