Dual Role of Doxorubicin for Photopolymerization and Therapy.

Doxorubicin / pharmacology Hydrophobic and Hydrophilic Interactions Methacrylates Nanoparticles Polymerization Polymers

Journal

Biomacromolecules
ISSN: 1526-4602
Titre abrégé: Biomacromolecules
Pays: United States
ID NLM: 100892849

Informations de publication

Date de publication:
14 09 2020
Historique:
pubmed: 14 8 2020
medline: 22 6 2021
entrez: 14 8 2020
Statut: ppublish

Résumé

In this study, we report dual roles for doxorubicin (DOX), which can serve as an antitumor drug as well as a cocatalyst for a photoliving radical polymerization. DOX enhances the polymerization rates of a broad range of monomers, including acrylamide, acrylate, and methacrylates, allowing for high monomer conversion and well-defined molecular weights under irradiation with a blue light-emitting diode light (λ

Identifiants

DOI: 10.1021/acs.biomac.0c01025 PMID: 32786533
pubmed: 32786533
doi: 10.1021/acs.biomac.0c01025
doi:

Substances chimiques

Methacrylates 0
Polymers 0
Doxorubicin 80168379AG

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3887-3897

Auteurs

Liwen Zhang (L)

Centre for Advanced Macromolecular Design, Australian Centre for NanoMedicine, School of Chemical Engineering, The University of New South Wales, Sydney, New South Wales 2052, Australia.

Lisi Xie (L)

Cancer Centre, Faculty of Health Sciences, University of Macau, Macau, SAR 999078, China.
Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macau, SAR 999078, China.

Sihao Xu (S)

Centre for Advanced Macromolecular Design, Australian Centre for NanoMedicine, School of Chemical Engineering, The University of New South Wales, Sydney, New South Wales 2052, Australia.

Rhiannon P Kuchel (RP)

Electron Microscope Unit, Mark Wainwright Analytical Centre, The University of New South Wales, Sydney, New South Wales 2052, Australia.

Yunlu Dai (Y)

Cancer Centre, Faculty of Health Sciences, University of Macau, Macau, SAR 999078, China.
Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macau, SAR 999078, China.
ORCID: 0000-0003-4023-7320

Kenward Jung (K)

Centre for Advanced Macromolecular Design, Australian Centre for NanoMedicine, School of Chemical Engineering, The University of New South Wales, Sydney, New South Wales 2052, Australia.

Cyrille Boyer (C)

Centre for Advanced Macromolecular Design, Australian Centre for NanoMedicine, School of Chemical Engineering, The University of New South Wales, Sydney, New South Wales 2052, Australia.
ORCID: 0000-0002-4564-4702

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Classifications MeSH

questionsmedicales.fr › Glucides › Hétérosides › Aminosides › Anthracyclines › Daunorubicine › Doxorubicine › Dual Role of Doxorubicin for...
questionsmedicales.fr › Phénomènes chimiques › Interactions hydrophobes et hydrophiles › Dual Role of Doxorubicin for...
questionsmedicales.fr › Composés chimiques organiques › Acides carboxyliques › Acides acycliques › Acrylates › Méthacrylates › Dual Role of Doxorubicin for...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Nanostructures › Nanoparticules › Dual Role of Doxorubicin for...
questionsmedicales.fr › Phénomènes chimiques › Polymérisation › Dual Role of Doxorubicin for...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Polymères › Dual Role of Doxorubicin for...