Liquid-liquid chromatography in enantioseparations.
Chiral selectors
Enantioseparation
Liquid-liquid chromatography
Review
Journal
Journal of chromatography. A
ISSN: 1873-3778
Titre abrégé: J Chromatogr A
Pays: Netherlands
ID NLM: 9318488
Informations de publication
Date de publication:
30 Aug 2020
30 Aug 2020
Historique:
received:
26
02
2020
revised:
12
06
2020
accepted:
12
06
2020
entrez:
17
8
2020
pubmed:
17
8
2020
medline:
30
9
2020
Statut:
ppublish
Résumé
Modern liquid-liquid chromatography mainly refers to the following two kinds of chromatographic apparatuses: countercurrent chromatography based on hydrodynamic equilibrium systems and centrifugal partition chromatography based on hydrostatic equilibrium systems. In this paper, the recent advancements in enantioseparations by liquid-liquid chromatography, including the separation mechanism, chiral selector, two-phase solvent system, methods to improve the peak resolution and recent applications, are reviewed. The future outlook for liquid-liquid chromatography in enantioseparations is also proposed.
Identifiants
pubmed: 32797825
pii: S0021-9673(20)30623-3
doi: 10.1016/j.chroma.2020.461345
pii:
doi:
Substances chimiques
Ligands
0
Solvents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
461345Informations de copyright
Copyright © 2020. Published by Elsevier B.V.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.