A Propensity Score Cohort Study on the Long-Term Safety and Efficacy of Sleeve Gastrectomy in Patients Older Than Age 60.


Journal

Journal of obesity
ISSN: 2090-0716
Titre abrégé: J Obes
Pays: United States
ID NLM: 101526295

Informations de publication

Date de publication:
2020
Historique:
received: 06 05 2020
accepted: 08 07 2020
entrez: 18 8 2020
pubmed: 18 8 2020
medline: 14 9 2021
Statut: epublish

Résumé

Bariatric surgery (BS) in older obese subjects (>60 years of age) has risen in the past decade and will continue to rise in the coming years due to ageing of the population. To evaluate the short- (12 months) and long-term (60 months) results of laparoscopic sleeve gastroscopy (LSG) in patients older than age 60. We performed a retrospective review of patients prospectively included in a database from January 2007 to December 2013. All patients >60 [older group (OG)] who had undergone LSG were included. The control group (CG) included patients aged 50 to 59 years who had undergone LSG during the same period. 116 (8.4 % of total surgery) and 145 patients were included in the OG and CG, respectively. BS in patients >60 years increased from 2.4% in 2003 to 14% in the last 2 years of the study. After inverse probability of treatment weighting (IPTW) analysis, all absolute standardized differences were <0.15. A 60-month follow-up was attained in 90% of patients in the OG and 74% in the CG. There were no significant differences in postoperative complications between the two groups. At 12 and 60 months after LSG, both groups achieved a similar body mass index. There was no statistical difference in the percentage of resolution of type 2 diabetes, hypertension, dyslipidemia, and SAHS between the two groups. In both groups, all the nutritional parameters evaluated remained within the normal range throughout the study. LSG provides acceptable outcomes and is safe in older adults indicating that age should not be a limitation to perform BS in this population.

Sections du résumé

Background
Bariatric surgery (BS) in older obese subjects (>60 years of age) has risen in the past decade and will continue to rise in the coming years due to ageing of the population.
Aim
To evaluate the short- (12 months) and long-term (60 months) results of laparoscopic sleeve gastroscopy (LSG) in patients older than age 60.
Methods
We performed a retrospective review of patients prospectively included in a database from January 2007 to December 2013. All patients >60 [older group (OG)] who had undergone LSG were included. The control group (CG) included patients aged 50 to 59 years who had undergone LSG during the same period.
Results
116 (8.4 % of total surgery) and 145 patients were included in the OG and CG, respectively. BS in patients >60 years increased from 2.4% in 2003 to 14% in the last 2 years of the study. After inverse probability of treatment weighting (IPTW) analysis, all absolute standardized differences were <0.15. A 60-month follow-up was attained in 90% of patients in the OG and 74% in the CG. There were no significant differences in postoperative complications between the two groups. At 12 and 60 months after LSG, both groups achieved a similar body mass index. There was no statistical difference in the percentage of resolution of type 2 diabetes, hypertension, dyslipidemia, and SAHS between the two groups. In both groups, all the nutritional parameters evaluated remained within the normal range throughout the study.
Conclusions
LSG provides acceptable outcomes and is safe in older adults indicating that age should not be a limitation to perform BS in this population.

Identifiants

pubmed: 32802499
doi: 10.1155/2020/8783260
pmc: PMC7416297
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

8783260

Informations de copyright

Copyright © 2020 Judith Molero et al.

Déclaration de conflit d'intérêts

The authors declare that they have no conflicts of interest.

Références

Rev Assoc Med Bras (1992). 2017 Sep;63(9):787-792
pubmed: 29239469
J Nutr Health Aging. 2016;20(7):780-8
pubmed: 27499312
Stat Med. 2009 Nov 10;28(25):3083-107
pubmed: 19757444
Clin Interv Aging. 2015 Oct 13;10:1627-35
pubmed: 26508845
Stat Med. 1998 Oct 15;17(19):2265-81
pubmed: 9802183
Med Clin North Am. 2018 Jan;102(1):65-85
pubmed: 29156188
Medicine (Baltimore). 2019 Jan;98(3):e13824
pubmed: 30653091
Ann Intern Med. 1991 Dec 15;115(12):956-61
pubmed: 1952493
Multivariate Behav Res. 2011 May;46(3):399-424
pubmed: 21818162
Scand J Surg. 2018 Mar;107(1):6-13
pubmed: 28942708
Ann Surg. 2009 Aug;250(2):187-96
pubmed: 19638912
Surg Obes Relat Dis. 2015 Mar-Apr;11(2):393-8
pubmed: 25130515
Surg Endosc. 2012 Jun;26(6):1744-50
pubmed: 22234587
Ann Surg. 2012 Dec;256(6):1023-9
pubmed: 22968072
Surg Obes Relat Dis. 2015 May-Jun;11(3):489-506
pubmed: 26093765

Auteurs

Judith Molero (J)

Endocrinology and Nutrition Department, Obesity Unit, Hospital Clinic, 170, Villarroel Street, Helios Office 9, Barcelona 08036, Spain.

Romina Olbeyra (R)

Institutd'Investigacions Biomèdiques August Pi Sunyer IDIBAPS, 180, Corcega Street, Barcelona 08036, Spain.

Josep Vidal (J)

Endocrinology and Nutrition Department, Obesity Unit, Hospital Clinic, 170, Villarroel Street, Helios Office 9, Barcelona 08036, Spain.
Institutd'Investigacions Biomèdiques August Pi Sunyer IDIBAPS, 180, Corcega Street, Barcelona 08036, Spain.
Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Barcelona, Spain.

Ferran Torres (F)

Biostatistics Unit, Faculty of Medicine, Universitat Autònoma de Barcelona, Medical Statistics Core Facility, IDIBAPS, Hospital Clinic Barcelona, Barcelona 08036, Spain.

Silvia Cañizares (S)

Endocrinology and Nutrition Department, Obesity Unit, Hospital Clinic, 170, Villarroel Street, Helios Office 9, Barcelona 08036, Spain.
Psychiatry and Psychology Department, Hospital Clinic, Department of Clinical Psychology and Psychobiosslogy, University of Barcelona, Barcelona 08036, Spain.

Alba Andreu (A)

Endocrinology and Nutrition Department, Obesity Unit, Hospital Clinic, 170, Villarroel Street, Helios Office 9, Barcelona 08036, Spain.

Ainitze Ibarzabal (A)

Department of Surgery, ICMDM, Hospital Clinic of Barcelona, Barcelona, Spain.
Gastrointestinal Surgery Department, Obesity Unit, Hospital Clínic de Barcelona, Barcelona, Spain.

Amanda Jiménez (A)

Endocrinology and Nutrition Department, Obesity Unit, Hospital Clinic, 170, Villarroel Street, Helios Office 9, Barcelona 08036, Spain.
Institutd'Investigacions Biomèdiques August Pi Sunyer IDIBAPS, 180, Corcega Street, Barcelona 08036, Spain.

Ana de Hollanda (A)

Endocrinology and Nutrition Department, Obesity Unit, Hospital Clinic, 170, Villarroel Street, Helios Office 9, Barcelona 08036, Spain.
Institutd'Investigacions Biomèdiques August Pi Sunyer IDIBAPS, 180, Corcega Street, Barcelona 08036, Spain.
Centro de Investigación Biomédica en Red, Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Barcelona, Spain.

Violeta Moizé (V)

Endocrinology and Nutrition Department, Obesity Unit, Hospital Clinic, 170, Villarroel Street, Helios Office 9, Barcelona 08036, Spain.

Lilliam Flores (L)

Endocrinology and Nutrition Department, Obesity Unit, Hospital Clinic, 170, Villarroel Street, Helios Office 9, Barcelona 08036, Spain.
Institutd'Investigacions Biomèdiques August Pi Sunyer IDIBAPS, 180, Corcega Street, Barcelona 08036, Spain.
Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Barcelona, Spain.

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