Vibrio deploys type 2 secreted lipase to esterify cholesterol with host fatty acids and mediate cell egress.


Journal

eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614

Informations de publication

Date de publication:
18 08 2020
Historique:
received: 19 04 2020
accepted: 28 07 2020
entrez: 19 8 2020
pubmed: 19 8 2020
medline: 13 2 2021
Statut: epublish

Résumé

Pathogens find diverse niches for survival including inside a host cell where replication occurs in a relatively protective environment.

Identifiants

pubmed: 32808593
doi: 10.7554/eLife.58057
pii: 58057
pmc: PMC7434443
doi:
pii:

Substances chimiques

Bacterial Proteins 0
Fatty Acids 0
Type III Secretion Systems 0
Cholesterol 97C5T2UQ7J
Lipase EC 3.1.1.3

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIGMS NIH HHS
ID : R35 GM137991
Pays : United States
Organisme : NIH HHS
ID : PO1 HL20948
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM113079
Pays : United States
Organisme : Welch Foundation
ID : I-1561
Pays : International
Organisme : NIH HHS
ID : R01 GM115188
Pays : United States
Organisme : NHLBI NIH HHS
ID : P01 HL020948
Pays : United States
Organisme : NIH HHS
ID : RO1 GM113079
Pays : United States

Informations de copyright

© 2020, Chimalapati et al.

Déclaration de conflit d'intérêts

SC, Md, AL, AR, WL, GR, GV, KP, MM, JM, JL No competing interests declared, KO Reviewing Editor, eLife

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Auteurs

Suneeta Chimalapati (S)

Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, United States.
Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, United States.

Marcela de Souza Santos (M)

Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, United States.

Alexander E Lafrance (AE)

Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, United States.

Ann Ray (A)

Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, United States.

Wan-Ru Lee (WR)

Department of Physiology, University of Texas Southwestern Medical Center, Dallas, United States.

Giomar Rivera-Cancel (G)

Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, United States.

Gonçalo Vale (G)

Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, United States.

Krzysztof Pawlowski (K)

Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, United States.
Faculty of Agriculture and Biology, Warsaw University of Life Sciences, Warsaw, Poland.

Matthew A Mitsche (MA)

Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, United States.
Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, United States.

Jeffrey G McDonald (JG)

Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, United States.
Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, United States.

Jen Liou (J)

Department of Physiology, University of Texas Southwestern Medical Center, Dallas, United States.

Kim Orth (K)

Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, United States.
Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, United States.
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, United States.

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Classifications MeSH