Impact of a dry inoculum deposition on the efficacy of copper-based antimicrobial surfaces.
Acinetobacter baumannii
/ drug effects
Aerosols
/ pharmacology
Alloys
Anti-Bacterial Agents
/ pharmacology
Anti-Infective Agents
/ pharmacology
Bacteria
/ drug effects
Coated Materials, Biocompatible
/ standards
Copper
/ pharmacology
Cross Infection
/ microbiology
Freeze Drying
Humidity
Microbial Viability
Staphylococcus aureus
/ drug effects
Surface Properties
Temperature
Acinetobacter baumannii
Aerosol
Antimicrobial surfaces
Copper
Staphylococcus aureus
Journal
The Journal of hospital infection
ISSN: 1532-2939
Titre abrégé: J Hosp Infect
Pays: England
ID NLM: 8007166
Informations de publication
Date de publication:
Nov 2020
Nov 2020
Historique:
received:
21
04
2020
accepted:
11
08
2020
pubmed:
19
8
2020
medline:
2
7
2021
entrez:
19
8
2020
Statut:
ppublish
Résumé
The introduction of antimicrobial surfaces into healthcare environments is believed to impact positively on the rate of healthcare-associated infections by significantly decreasing pathogen presence on surfaces. To report on a novel efficacy test that uses a dry bacterial inoculum to measure the microbicidal efficacy of antimicrobial surfaces. An aerosolized dry inoculum of Staphylococcus aureus or Acinetobacter baumannii was deposited on copper alloy surfaces or a hospital-grade stainless-steel surface. Surviving bacteria were enumerated following incubation of the inoculated surfaces at an environmentally relevant temperature and relative humidity. Damage caused to bacteria by the aerosolization process and by the different surfaces was investigated. Dry inoculum testing showed a <2-log Our test provided a realistic deposition of a bacterial inoculum to a surface and, as such, a realistic protocol to assess the efficacy of dry antimicrobial environmental surfaces in vitro.
Sections du résumé
BACKGROUND
BACKGROUND
The introduction of antimicrobial surfaces into healthcare environments is believed to impact positively on the rate of healthcare-associated infections by significantly decreasing pathogen presence on surfaces.
AIM
OBJECTIVE
To report on a novel efficacy test that uses a dry bacterial inoculum to measure the microbicidal efficacy of antimicrobial surfaces.
METHODS
METHODS
An aerosolized dry inoculum of Staphylococcus aureus or Acinetobacter baumannii was deposited on copper alloy surfaces or a hospital-grade stainless-steel surface. Surviving bacteria were enumerated following incubation of the inoculated surfaces at an environmentally relevant temperature and relative humidity. Damage caused to bacteria by the aerosolization process and by the different surfaces was investigated.
FINDINGS
RESULTS
Dry inoculum testing showed a <2-log
CONCLUSIONS
CONCLUSIONS
Our test provided a realistic deposition of a bacterial inoculum to a surface and, as such, a realistic protocol to assess the efficacy of dry antimicrobial environmental surfaces in vitro.
Identifiants
pubmed: 32810570
pii: S0195-6701(20)30391-1
doi: 10.1016/j.jhin.2020.08.013
pii:
doi:
Substances chimiques
Aerosols
0
Alloys
0
Anti-Bacterial Agents
0
Anti-Infective Agents
0
Coated Materials, Biocompatible
0
Copper
789U1901C5
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
465-472Informations de copyright
Copyright © 2020. Published by Elsevier Ltd.