Interferon-λ at the Center of the Storm.

Animals Antiviral Agents Interferons Lung Mice Interferon Lambda

Journal

Immunity
ISSN: 1097-4180
Titre abrégé: Immunity
Pays: United States
ID NLM: 9432918

Informations de publication

Date de publication:
18 08 2020
Historique:
entrez: 20 8 2020
pubmed: 20 8 2020
medline: 7 4 2021
Statut: ppublish

Résumé

Type I and III interferons (IFNs) drive effective antiviral functions but differentially affect tissue homeostasis. Using mouse models of severe inflammation, Broggi et al. and Major et al. report in Science that type III IFNs disrupt epithelial cell proliferation and differentiation in the lung.

Identifiants

DOI: 10.1016/j.immuni.2020.07.024 PMID: 32814024 PMC: PMC7434483
pubmed: 32814024
pii: S1074-7613(20)30331-9
doi: 10.1016/j.immuni.2020.07.024
pmc: PMC7434483
pii:
doi:

Substances chimiques

Antiviral Agents 0
Interferons 9008-11-1
Interferon Lambda 0

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

245-247

Commentaires et corrections

Type : CommentOn
Type : CommentOn

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Références

Science. 2015 Jan 16;347(6219):269-73
pubmed: 25431489
Elife. 2018 Apr 13;7:
pubmed: 29651984
Science. 2020 Aug 7;369(6504):712-717
pubmed: 32527928
Nat Immunol. 2017 Oct;18(10):1084-1093
pubmed: 28846084
Science. 2020 Aug 7;369(6504):706-712
pubmed: 32527925
Nat Immunol. 2014 Jan;15(1):72-9
pubmed: 24241692
Trends Immunol. 2018 Oct;39(10):848-858
pubmed: 30219309
Sci Transl Med. 2015 Apr 22;7(284):284ra59
pubmed: 25904743
Front Immunol. 2017 Dec 06;8:1707
pubmed: 29270173
Immunity. 2019 Sep 17;51(3):451-464.e6
pubmed: 31471108
Nat Immunol. 2019 Aug;20(8):1035-1045
pubmed: 31235953
Immunity. 2017 May 16;46(5):875-890.e6
pubmed: 28514692

Auteurs

Matthew R Hendricks (MR)

Department of Immunology, University of Washington, Seattle, WA 98109, USA.

Ram Savan (R)

Department of Immunology, University of Washington, Seattle, WA 98109, USA. Electronic address: savanram@uw.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Interferon-λ at the Center of the Storm.
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiviraux › Interferon-λ at the Center of the Storm.
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Interférons › Interferon-λ at the Center of the Storm.
questionsmedicales.fr › Appareil respiratoire › Poumon › Interferon-λ at the Center of the Storm.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Interferon-λ at the Center of the Storm.
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Interférons › Interféron lambda › Interferon-λ at the Center of the Storm.