Mediastinal Germ Cell Tumor and Acute Megakaryoblastic Leukemia With Co-occurring KRAS Mutation and Complex Cytogenetics.


Journal

Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
ISSN: 1615-5742
Titre abrégé: Pediatr Dev Pathol
Pays: United States
ID NLM: 9809673

Informations de publication

Date de publication:
Historique:
pubmed: 21 8 2020
medline: 7 9 2021
entrez: 21 8 2020
Statut: ppublish

Résumé

Young males have a unique but rare predilection to develop mediastinal nonseminomatous germ cell tumors (NSGCTs) and concomitant acute megakaryoblastic leukemia (AMKL). Common cytogenetic and molecular abnormalities such as isochromosome 12p and somatic Tumor Protein P53(TP53) and

Identifiants

pubmed: 32815783
doi: 10.1177/1093526620951327
doi:

Substances chimiques

Biomarkers, Tumor 0
KRAS protein, human 0
MAS1 protein, human 0
Proto-Oncogene Mas 0
Proto-Oncogene Proteins p21(ras) EC 3.6.5.2

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

461-466

Auteurs

Nasir Amra (N)

Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas.

Luis Velasquez Zarate (LV)

Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas.

Jyotinder N Punia (JN)

Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas.

Priya Mahajan (P)

Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas.

Alexandra M Stevens (AM)

Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas.

Angshumoy Roy (A)

Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas.

Choladda V Curry (CV)

Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas.

Nahir Cortes-Santiago (N)

Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas.

Kevin E Fisher (KE)

Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas.

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Classifications MeSH