An update on autoimmune retinopathy.
Autoimmune retinopathy
cancer-associated retinopathy
enolase
melanoma-associated retinopathy
recoverin
Journal
Indian journal of ophthalmology
ISSN: 1998-3689
Titre abrégé: Indian J Ophthalmol
Pays: India
ID NLM: 0405376
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
entrez:
23
8
2020
pubmed:
23
8
2020
medline:
15
5
2021
Statut:
ppublish
Résumé
Autoimmune retinopathy (AIR) refers to a group of rare autoimmune retinal degenerative diseases presumably caused by cross-reactivity of serum autoantibodies against retinal antigens. The pathogenesis of AIR remains largely presumptive and there are a significant number of antiretinal antibodies that have been detected in association with AIR. The diagnosis of AIR is largely based on the demonstration of antiretinal antibodies in the serum along with suggestive clinical features and ancillary investigations. A high index of suspicion along with early diagnosis and treatment may play a critical role to lower the risk of irreversible immunological damage to the retinal cells in these patients. A multi-disciplinary approach for complete management and evaluation is helpful in such conditions. Various therapeutic options have been described for the treatment of AIR, though there is no consensus on standard treatment protocol.
Identifiants
pubmed: 32823399
pii: IndianJOphthalmol_2020_68_9_1829_292587
doi: 10.4103/ijo.IJO_786_20
pmc: PMC7690499
doi:
Substances chimiques
Autoantibodies
0
Autoantigens
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1829-1837Déclaration de conflit d'intérêts
None
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