Clinical Features at Onset and Genetic Characterization of Pediatric and Adult Patients with TNF-


Journal

Mediators of inflammation
ISSN: 1466-1861
Titre abrégé: Mediators Inflamm
Pays: United States
ID NLM: 9209001

Informations de publication

Date de publication:
2020
Historique:
received: 08 04 2020
accepted: 19 06 2020
entrez: 25 8 2020
pubmed: 25 8 2020
medline: 17 7 2021
Statut: epublish

Résumé

This study explores demographic, clinical, and therapeutic features of tumor necrosis factor receptor-associated periodic syndrome (TRAPS) in a cohort of 80 patients recruited from 19 Italian referral Centers. Patients' data were collected retrospectively and then analyzed according to age groups (disease onset before or after 16 years) and genotype (high penetrance (HP) and low penetrance (LP)

Identifiants

pubmed: 32831641
doi: 10.1155/2020/8562485
pmc: PMC7428902
doi:

Substances chimiques

Receptors, Tumor Necrosis Factor, Type I 0
TNFRSF1A protein, human 0
Tumor Necrosis Factor-alpha 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

8562485

Informations de copyright

Copyright © 2020 Carla Gaggiano et al.

Déclaration de conflit d'intérêts

The authors declare that they have no conflicts of interest.

Références

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Auteurs

Carla Gaggiano (C)

Clinical Pediatrics, Department of Molecular Medicine and Development, University of Siena, Siena, Italy.

Antonio Vitale (A)

Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.

Laura Obici (L)

Amyloidosis Research and Treatment Center, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

Giampaolo Merlini (G)

Amyloidosis Research and Treatment Center, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

Alessandra Soriano (A)

Department of Internal Medicine, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy.

Ombretta Viapiana (O)

Rheumatology Section, Department of Medicine, University of Verona, Verona, Italy.

Marco Cattalini (M)

Paediatric Clinic, University of Brescia and Spedali Civili di Brescia, Brescia, Italy.

Maria Cristina Maggio (MC)

Universitary Department "Pro.S.A.M.I.", University of Palermo, Palermo, Italy.

Giuseppe Lopalco (G)

Rheumatology Unit, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy.

Davide Montin (D)

Division of Immunology and Rheumatology, Department of Paediatric Infectious Diseases, University of Turin, Regina Margherita Children's Hospital, Turin, Italy.

Masen Abdel Jaber (MA)

Rheumatology Unit, Santa Chiara Hospital, Trento, Italy.

Lorenzo Dagna (L)

Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Scientific Institute, Milan, Italy.
Department of Internal Medicine, Vita-Salute San Raffaele University, Milan, Italy.

Raffaele Manna (R)

Periodic Fever Research Center, Institute of Internal Medicine, Catholic University of the Sacred Heart, Fondazione Policlinico A. Gemelli, Rome, Italy.

Antonella Insalaco (A)

Division of Rheumatology, Department of Pediatric Medicine, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Matteo Piga (M)

Rheumatology Unit, Department of Medical Sciences, University and AOU of Cagliari, Cagliari, Italy.

Francesco La Torre (F)

Clinical Pediatrics, University of Bari, Bari, Italy.

Virginia Berlengiero (V)

Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.

Viviana Gelardi (V)

Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.

Luisa Ciarcia (L)

Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.

Giacomo Emmi (G)

Department of Experimental and Clinical Medicine, University of Firenze, Florence, Italy.

Piero Ruscitti (P)

Rheumatology Unit, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Italy.

Francesco Caso (F)

Rheumatology Unit, Department of Clinical Medicine and Surgery, School of Medicine and Surgery, University Federico II, Naples, Italy.

Rolando Cimaz (R)

Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Rheumatology Unit, A. Meyer Children's Hospital, Florence, Italy.

José Hernández-Rodríguez (J)

Vasculitis Research Unit and Autoinflammatory Diseases Clinical Unit, Department of Autoimmune Diseases, Hospital Clinic of Barcelona, IDIBAPS, University of Barcelona, Barcelona, Spain.

Paola Parronchi (P)

Department of Experimental and Clinical Medicine, University of Firenze, Florence, Italy.

Ludovico Luca Sicignano (LL)

Periodic Fever Research Center, Institute of Internal Medicine, Catholic University of the Sacred Heart, Fondazione Policlinico A. Gemelli, Rome, Italy.

Elena Verrecchia (E)

Periodic Fever Research Center, Institute of Internal Medicine, Catholic University of the Sacred Heart, Fondazione Policlinico A. Gemelli, Rome, Italy.

Florenzo Iannone (F)

Rheumatology Unit, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy.

Jurgen Sota (J)

Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.

Salvatore Grosso (S)

Clinical Pediatrics, Department of Molecular Medicine and Development, University of Siena, Siena, Italy.

Carlo Salvarani (C)

Department of Internal Medicine, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy.

Bruno Frediani (B)

Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.

Roberto Giacomelli (R)

Rheumatology Unit, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Italy.

Maria Antonietta Mencarelli (MA)

Genetica Medica, Azienda Ospedaliera Universitaria Senese, Siena, Italy.

Alessandra Renieri (A)

Genetica Medica, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
Medical Genetics, University of Siena, Siena, Italy.

Donato Rigante (D)

Institute of Pediatrics, Periodic Fever Research Center, Università Cattolica Sacro Cuore, Fondazione Policlinico A. Gemelli, IRCCS, Rome, Italy.

Luca Cantarini (L)

Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.

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Classifications MeSH