Medication-related osteonecrosis of the mandible: an unusual presentation and treatment.
bisphosphonates
medication-related osteonecrosis of the jaw (MRONJ)
neo-mandible
resection of the mandible
treatment
Journal
International journal of oral and maxillofacial surgery
ISSN: 1399-0020
Titre abrégé: Int J Oral Maxillofac Surg
Pays: Denmark
ID NLM: 8605826
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
received:
24
04
2020
revised:
09
06
2020
accepted:
29
07
2020
pubmed:
28
8
2020
medline:
18
3
2021
entrez:
28
8
2020
Statut:
ppublish
Résumé
A 71-year-old woman was referred to the clinic with extensive medication-related osteonecrosis of the jaw (MRONJ) involving the mandible. She had received 7 years of zoledronate therapy. On cone beam computed tomography, the MRONJ presented as a large sequestrum spanning from the left to the right condylar process, surrounded by thick sub-periosteal bone. The sequestrum was excised via an intraoral approach, leaving the newly formed sub-periosteal bone as a neo-mandible. The patient recovered well from the operation and was discharged 5 days after surgery. She healed completely without complications. This case report presents an alternative surgical treatment that may be considered if there is clinically stable sub-periosteal bone surrounding extensive MRONJ.
Identifiants
pubmed: 32847710
pii: S0901-5027(20)30296-4
doi: 10.1016/j.ijom.2020.07.033
pii:
doi:
Substances chimiques
Bone Density Conservation Agents
0
Zoledronic Acid
6XC1PAD3KF
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
511-515Informations de copyright
Copyright © 2020 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.