Pea-derived peptides, VLP, LLP, VA, and LL, improve insulin resistance in HepG2 cells via activating IRS-1/PI3K/AKT and blocking ROS-mediated p38MAPK signaling.
hypoglycemic
insulin resistance
oxidative stress
peptides
Journal
Journal of food biochemistry
ISSN: 1745-4514
Titre abrégé: J Food Biochem
Pays: United States
ID NLM: 7706045
Informations de publication
Date de publication:
11 2020
11 2020
Historique:
received:
20
04
2020
revised:
03
08
2020
accepted:
06
08
2020
pubmed:
3
9
2020
medline:
27
5
2021
entrez:
3
9
2020
Statut:
ppublish
Résumé
This study evaluated the effect of four peptides, VLP, LLP, LL, and LL from pea on regulating glucose metabolism and antioxidant through IRS-1/PI3K/AKT and p38MAPK signal pathway in IR-HepG2 cell induced by 10
Substances chimiques
Peptides
0
Plant Extracts
0
Reactive Oxygen Species
0
Proto-Oncogene Proteins c-akt
EC 2.7.11.1
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13454Informations de copyright
© 2020 Wiley Periodicals LLC.
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