Effects of Stellate Ganglion Block on Healing of Fractures Induced in Rats.
Acetaminophen
/ pharmacology
Analgesics, Non-Narcotic
/ pharmacology
Animals
Autonomic Nerve Block
/ methods
Cartilage, Articular
/ physiopathology
Forelimb
/ injuries
Fracture Healing
/ physiology
Fractures, Closed
/ diagnostic imaging
Male
Osteogenesis
/ physiology
Rats, Wistar
Stellate Ganglion
/ drug effects
Journal
BioMed research international
ISSN: 2314-6141
Titre abrégé: Biomed Res Int
Pays: United States
ID NLM: 101600173
Informations de publication
Date de publication:
2020
2020
Historique:
received:
04
01
2020
revised:
13
06
2020
accepted:
23
07
2020
entrez:
4
9
2020
pubmed:
4
9
2020
medline:
28
5
2021
Statut:
epublish
Résumé
Sympathetic blocks are used as an adjunct for pain management in the treatment of orthopedic and traumatic conditions. Stellate ganglion (ganglion stellatum) provides sympathetic innervation of the head, neck and cervicothoracic regions, and upper extremities. No study was found in the literature investigating the effects of stellate ganglion block performed in the upper extremity, on blood supply to bone, density, vascularization, and bone metabolism. Therefore, the objective of this study was to investigate the effects of stellate ganglion block on healing of closed forearm fractures that were induced in rats. When histological findings of the fracture region were examined, predominantly cartilage and less woven bone were found in 7 rats, equally distributed cartilage and immature bone in 14 rats, and predominantly imitation bone and less cartilage formation in 21 rats. In the control group, the agreement between the 1st and 2nd orthopedists for the radiological evaluation of bone formation was moderate. The group administered stellate ganglion block showed a more significant fracture healing.
Identifiants
pubmed: 32879882
doi: 10.1155/2020/4503463
pmc: PMC7448117
doi:
Substances chimiques
Analgesics, Non-Narcotic
0
Acetaminophen
362O9ITL9D
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
4503463Informations de copyright
Copyright © 2020 Hasan Kizilay et al.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest regarding the present study.
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