Impact of salt and the osmoprotective transcription factor NFAT-5 on macrophages during mechanical strain.
Macrophages
NFAT-5
orthodontics
salt
sodium chloride
Journal
Immunology and cell biology
ISSN: 1440-1711
Titre abrégé: Immunol Cell Biol
Pays: United States
ID NLM: 8706300
Informations de publication
Date de publication:
01 2021
01 2021
Historique:
received:
21
04
2020
revised:
10
07
2020
revised:
02
09
2020
accepted:
02
09
2020
pubmed:
6
9
2020
medline:
29
9
2021
entrez:
5
9
2020
Statut:
ppublish
Résumé
Myeloid cells regulate bone density in response to increased salt (NaCl) intake via the osmoprotective transcription factor, nuclear factor of activated T cells-5 (NFAT-5). Because orthodontic tooth movement (OTM) is a pseudoinflammatory immunological process, we investigated the influence of NaCl and NFAT-5 on the expression pattern of macrophages in a model of simulated OTM. RAW264.7 macrophages were exposed for 4 h to 2 g cm
Substances chimiques
Sodium Chloride, Dietary
0
Transcription Factors
0
Sodium Chloride
451W47IQ8X
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
84-96Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2020 The Authors. Immunology & Cell Biology published by John Wiley & Sons Australia, Ltd on behalf of Australian and New Zealand Society for Immunology, Inc.
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