Is the introduction of more advanced radiotherapy techniques for locally-advanced head and neck cancer associated with improved quality of life and reduced symptom burden?

Head and neck radiotherapy Organ at risk sparing Patient reported outcome Quality of life

Journal

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
ISSN: 1879-0887
Titre abrégé: Radiother Oncol
Pays: Ireland
ID NLM: 8407192

Informations de publication

Date de publication:
10 2020
Historique:
received: 21 04 2020
revised: 21 08 2020
accepted: 27 08 2020
pubmed: 6 9 2020
medline: 15 4 2021
entrez: 5 9 2020
Statut: ppublish

Résumé

Technical improvements in head and neck cancer radiotherapy over the last decade have resulted in substantial reductions in dose to organs-at-risk. For a mix of tumors, we saw less xerostomia moving from 3D-conformal to more advanced techniques. For oropharynx-only there were additional improvements, including in global quality-of-life and sticky saliva.

Identifiants

pubmed: 32890608
pii: S0167-8140(20)30755-6
doi: 10.1016/j.radonc.2020.08.026
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

298-303

Informations de copyright

Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.

Auteurs

Max Dahele (M)

Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Radiation Oncology, Cancer Center Amsterdam, Netherlands.

Jim P Tol (JP)

Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Radiation Oncology, Cancer Center Amsterdam, Netherlands.

Marije R Vergeer (MR)

Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Radiation Oncology, Cancer Center Amsterdam, Netherlands.

Femke Jansen (F)

Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Otolaryngology-Head and Neck Surgery, Cancer Center Amsterdam, Netherlands.

Birgit I Lissenberg-Witte (BI)

Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Epidemiology and Data Science, Netherlands.

C Rene Leemans (CR)

Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Otolaryngology-Head and Neck Surgery, Cancer Center Amsterdam, Netherlands.

Ben J Slotman (BJ)

Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Radiation Oncology, Cancer Center Amsterdam, Netherlands.

Irma M Verdonck-de Leeuw (IM)

Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Otolaryngology-Head and Neck Surgery, Cancer Center Amsterdam, Netherlands.

Wilko F A R Verbakel (WFAR)

Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Radiation Oncology, Cancer Center Amsterdam, Netherlands. Electronic address: w.verbakel@amsterdamumc.nl.

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Classifications MeSH